Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
暂无分享,去创建一个
[1] S. Krane,et al. Stromal regulation of vessel stability by MMP14 and TGFβ , 2010, Disease Models & Mechanisms.
[2] Z. Werb,et al. Matrix metalloproteinases contribute distinct roles in neuroendocrine prostate carcinogenesis, metastasis, and angiogenesis progression. , 2010, Cancer research.
[3] M. Terol,et al. Matrix metalloproteinase-9 promotes chronic lymphocytic leukemia b cell survival through its hemopexin domain. , 2010, Cancer cell.
[4] Mikala Egeblad,et al. Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling , 2009, Cell.
[5] Yao‐Hua Song,et al. Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion. , 2009, Cancer letters.
[6] P. Scherer,et al. Mechanisms of obesity and related pathologies: The macro‐ and microcirculation of adipose tissue , 2009, The FEBS journal.
[7] Hubing Shi,et al. Pulmonary vascular destabilization in the premetastatic phase facilitates lung metastasis. , 2009, Cancer research.
[8] Qiongqing Wang,et al. ADAMTS1 and MMP1 proteolytically engage EGF-like ligands in an osteolytic signaling cascade for bone metastasis. , 2009, Genes & development.
[9] A. M. Houghton,et al. Macrophage elastase kills bacteria within murine macrophages , 2009, Nature.
[10] P. E. Van den Steen,et al. Neutrophil MMP-9 Proenzyme, Unencumbered by TIMP-1, Undergoes Efficient Activation in Vivo and Catalytically Induces Angiogenesis via a Basic Fibroblast Growth Factor (FGF-2)/FGFR-2 Pathway* , 2009, The Journal of Biological Chemistry.
[11] H. Saji,et al. Development of a radiolabeled probe for detecting membrane type-1 matrix metalloproteinase on malignant tumors. , 2009, Biological & pharmaceutical bulletin.
[12] Cheng-Zhong Zhang,et al. Mechanoenzymatic Cleavage of the Ultralarge Vascular Protein von Willebrand Factor , 2009, Science.
[13] Raghu Kalluri,et al. The basics of epithelial-mesenchymal transition. , 2009, The Journal of clinical investigation.
[14] Z. Werb,et al. Netting neutrophils in autoimmune small-vessel vasculitis , 2009, Nature Medicine.
[15] Roger Y Tsien,et al. In vivo characterization of activatable cell penetrating peptides for targeting protease activity in cancer. , 2009, Integrative biology : quantitative biosciences from nano to macro.
[16] D. Ribatti. Endogenous inhibitors of angiogenesis: a historical review. , 2009, Leukemia research.
[17] M. Seiki,et al. Cytoplasmic tail of MT1‐MMP regulates macrophage motility independently from its protease activity , 2009, Genes to cells : devoted to molecular & cellular mechanisms.
[18] F. Balkwill. Tumour necrosis factor and cancer , 2009, Nature Reviews Cancer.
[19] Chenwei Wang,et al. Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma , 2009, Nature Genetics.
[20] Stephen J. Weiss,et al. Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited , 2009, The Journal of cell biology.
[21] G. Opdenakker,et al. Synergistic up‐regulation of MCP‐2/CCL8 activity is counteracted by chemokine cleavage, limiting its inflammatory and anti‐tumoral effects , 2009, European journal of immunology.
[22] W. Fu,et al. Leptin induces migration and invasion of glioma cells through MMP‐13 production , 2009, Glia.
[23] B. Glasheen,et al. Distinct functions for the catalytic and hemopexin domains of a Drosophila matrix metalloproteinase , 2009, Proceedings of the National Academy of Sciences.
[24] M. Lepage,et al. New enzyme-activated solubility-switchable contrast agent for magnetic resonance imaging: from synthesis to in vivo imaging. , 2009, Journal of medicinal chemistry.
[25] Valerie M. Weaver,et al. A tense situation: forcing tumour progression , 2009, Nature Reviews Cancer.
[26] J. Erler,et al. Hypoxia-induced lysyl oxidase is a critical mediator of bone marrow cell recruitment to form the premetastatic niche. , 2009, Cancer cell.
[27] D. Albertson,et al. Rac 1 b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability , 2009 .
[28] Kenneth M. Yamada,et al. Direct visualization of protease activity on cells migrating in three-dimensions. , 2009, Matrix Biology.
[29] G. Murphy. The ADAMs: signalling scissors in the tumour microenvironment , 2008, Nature Reviews Cancer.
[30] A. Dufour,et al. Role of the hemopexin domain of matrix metalloproteinases in cell migration , 2008, Journal of cellular physiology.
[31] J. Foidart,et al. ADAMTS-1 metalloproteinase promotes tumor development through the induction of a stromal reaction in vivo. , 2008, Cancer research.
[32] Xiaodong Li,et al. Predictive value of MMP‐7 expression for response to chemotherapy and survival in patients with non‐small cell lung cancer , 2008, Cancer science.
[33] Hiroyuki Aburatani,et al. The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase , 2008, Nature Cell Biology.
[34] A. Czirók,et al. Matrix metalloproteinase 2-integrin alpha(v)beta3 binding is required for mesenchymal cell invasive activity but not epithelial locomotion: a computational time-lapse study. , 2008, Molecular biology of the cell.
[35] Peter Friedl,et al. Tube travel: the role of proteases in individual and collective cancer cell invasion. , 2008, Cancer research.
[36] J. Fridman,et al. Synergistic inhibition with a dual epidermal growth factor receptor/HER-2/neu tyrosine kinase inhibitor and a disintegrin and metalloprotease inhibitor. , 2008, Cancer research.
[37] Mikala Egeblad,et al. Visualizing stromal cell dynamics in different tumor microenvironments by spinning disk confocal microscopy , 2008, Disease Models & Mechanisms.
[38] D. Edwards,et al. The ADAM metalloproteinases , 2008, Molecular Aspects of Medicine.
[39] J. Keski‐Oja,et al. MT1-MMP releases latent TGF-beta1 from endothelial cell extracellular matrix via proteolytic processing of LTBP-1. , 2008, Experimental cell research.
[40] E. Motrescu,et al. Cancer cells, adipocytes and matrix metalloproteinase 11: a vicious tumor progression cycle , 2008, Biological chemistry.
[41] H. Rammensee,et al. Tumor-associated MICA is shed by ADAM proteases. , 2008, Cancer research.
[42] J. Massagué,et al. TGFβ in Cancer , 2008, Cell.
[43] Christopher M. Overall,et al. Matrix Metalloproteinase Processing of CXCL11/I-TAC Results in Loss of Chemoattractant Activity and Altered Glycosaminoglycan Binding* , 2008, Journal of Biological Chemistry.
[44] D. Missé,et al. Potentiation of NK cell-mediated cytotoxicity in human lung adenocarcinoma: role of NKG2D-dependent pathway. , 2008, International immunology.
[45] Karen D. Cowden Dahl,et al. Matrix metalloproteinase 9 is a mediator of epidermal growth factor-dependent e-cadherin loss in ovarian carcinoma cells. , 2008, Cancer research.
[46] C. Smas,et al. Wdnm1-like, a new adipokine with a role in MMP-2 activation. , 2008, American journal of physiology. Endocrinology and metabolism.
[47] L. Matrisian,et al. Imaging matrix metalloproteinases in cancer , 2008, Cancer and Metastasis Reviews.
[48] L. Matrisian,et al. Optical Imaging of Matrix Metalloproteinase-7 Activity in Vivo Using a Proteolytic Nanobeacon , 2008, Molecular imaging.
[49] P. Carmeliet,et al. Modeling lymphangiogenesis in a three-dimensional culture system , 2008, Nature Methods.
[50] X. Puente,et al. Matrix metalloproteinase-8 functions as a metastasis suppressor through modulation of tumor cell adhesion and invasion. , 2008, Cancer research.
[51] S. Vandenberg,et al. HIF1alpha induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion. , 2008, Cancer cell.
[52] G. Ahn,et al. Matrix metalloproteinase-9 is required for tumor vasculogenesis but not for angiogenesis: role of bone marrow-derived myelomonocytic cells. , 2008, Cancer cell.
[53] Anne M Manicone,et al. Matrix metalloproteinases as modulators of inflammation. , 2008, Seminars in cell & developmental biology.
[54] Alfredo Molinolo,et al. Matrix Metalloproteinase-activated Anthrax Lethal Toxin Demonstrates High Potency in Targeting Tumor Vasculature* , 2008, Journal of Biological Chemistry.
[55] J. Quigley,et al. Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis , 2007, Proceedings of the National Academy of Sciences.
[56] C. López-Otín,et al. Emerging roles of proteases in tumour suppression , 2007, Nature Reviews Cancer.
[57] Viola Vogel,et al. Force-Induced Unfolding of Fibronectin in the Extracellular Matrix of Living Cells , 2007, PLoS biology.
[58] M. Stack,et al. Multi-step pericellular proteolysis controls the transition from individual to collective cancer cell invasion , 2007, Nature Cell Biology.
[59] Carlos López-Otín,et al. The FASEB Journal • Research Communication Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8) , 2022 .
[60] A. Küpelioğlu,et al. Matrix metalloproteinase‐9,‐3 and tissue inhibitor of matrix metalloproteinase‐1 in colorectal cancer: relationship to clinicopathological variables , 2007, Cell biochemistry and function.
[61] B. Strooper,et al. ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death , 2007, Cell Death and Differentiation.
[62] Wan-Wan Lin,et al. A cytokine-mediated link between innate immunity, inflammation, and cancer. , 2007, The Journal of clinical investigation.
[63] Andrew J. Ewald,et al. Matrix metalloproteinases and the regulation of tissue remodelling , 2007, Nature Reviews Molecular Cell Biology.
[64] Hiroyuki Aburatani,et al. Tumour-mediated upregulation of chemoattractants and recruitment of myeloid cells predetermines lung metastasis , 2006, Nature Cell Biology.
[65] Kevin Wei,et al. A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development , 2006, The Journal of experimental medicine.
[66] Christopher Chiu,et al. Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis , 2006, Proceedings of the National Academy of Sciences.
[67] A. M. Houghton,et al. Macrophage elastase (matrix metalloproteinase-12) suppresses growth of lung metastases. , 2006, Cancer research.
[68] Stephen J. Weiss,et al. A Pericellular Collagenase Directs the 3-Dimensional Development of White Adipose Tissue , 2006, Cell.
[69] G. Opdenakker,et al. Dystroglycan is selectively cleaved at the parenchymal basement membrane at sites of leukocyte extravasation in experimental autoimmune encephalomyelitis , 2006, The Journal of experimental medicine.
[70] J. Quigley,et al. Matrix metalloproteinases and tumor metastasis , 2006, Cancer and Metastasis Reviews.
[71] A. M. Houghton,et al. Elastin fragments drive disease progression in a murine model of emphysema. , 2006, The Journal of clinical investigation.
[72] Gillian Murphy,et al. Structure and function of matrix metalloproteinases and TIMPs. , 2006, Cardiovascular research.
[73] A. Kraneveld,et al. A novel peptide CXCR ligand derived from extracellular matrix degradation during airway inflammation , 2006, Nature Medicine.
[74] Jeffrey T. Chang,et al. Oncogenic pathway signatures in human cancers as a guide to targeted therapies , 2006, Nature.
[75] L. Coussens,et al. Paradoxical roles of the immune system during cancer development , 2006, Nature Reviews Cancer.
[76] S. Rafii,et al. VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche , 2005, Nature.
[77] T. Salo,et al. Generation of biologically active endostatin fragments from human collagen XVIII by distinct matrix metalloproteases. , 2005, Experimental cell research.
[78] D. Albertson,et al. Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability , 2005, Nature.
[79] H. Lane,et al. ERBB Receptors and Cancer: The Complexity of Targeted Inhibitors , 2005, Nature Reviews Cancer.
[80] B. de Strooper,et al. ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and beta-catenin translocation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[81] M. Luisa Iruela-Arispe,et al. Processing of VEGF-A by matrix metalloproteinases regulates bioavailability and vascular patterning in tumors , 2005, The Journal of cell biology.
[82] Tomoyuki Shirai,et al. MMP-7 promotes prostate cancer-induced osteolysis via the solubilization of RANKL. , 2005, Cancer cell.
[83] P Cuniasse,et al. Future challenges facing the development of specific active-site-directed synthetic inhibitors of MMPs. , 2005, Biochimie.
[84] A. Agarwal,et al. PAR1 Is a Matrix Metalloprotease-1 Receptor that Promotes Invasion and Tumorigenesis of Breast Cancer Cells , 2005, Cell.
[85] M. Langenskiöld,et al. Increased plasma MMP-2 protein expression in lymph node-positive patients with colorectal cancer , 2005, International Journal of Colorectal Disease.
[86] Roger Y Tsien,et al. Tumor imaging by means of proteolytic activation of cell-penetrating peptides. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[87] A. Godzik,et al. Non-proteolytic, Receptor/Ligand Interactions Associate Cellular Membrane Type-1 Matrix Metalloproteinase with the Complement Component C1q* , 2004, Journal of Biological Chemistry.
[88] Steven Shapiro,et al. Tumor cell traffic through the extracellular matrix is controlled by the membrane-anchored collagenase MT1-MMP , 2004, The Journal of cell biology.
[89] J. Pollard,et al. A Paracrine Loop between Tumor Cells and Macrophages Is Required for Tumor Cell Migration in Mammary Tumors , 2004, Cancer Research.
[90] M. Karin,et al. Inhibition of NF-κB in cancer cells converts inflammation- induced tumor growth mediated by TNFα to TRAIL-mediated tumor regression , 2004 .
[91] William C. Parks,et al. Matrix metalloproteinases as modulators of inflammation and innate immunity , 2004, Nature Reviews Immunology.
[92] Otmar Schober,et al. Scintigraphic Imaging of Matrix Metalloproteinase Activity in the Arterial Wall In Vivo , 2004, Circulation.
[93] A. Zychlinsky,et al. Neutrophil Extracellular Traps Kill Bacteria , 2004, Science.
[94] K. Conant,et al. Matrix Metalloproteinase 1 Interacts with Neuronal Integrins and Stimulates Dephosphorylation of Akt* , 2004, Journal of Biological Chemistry.
[95] I. Saiki,et al. Inhibition of lymphangiogenesis‐related properties of murine lymphatic endothelial cells and lymph node metastasis of lung cancer by the matrix metalloproteinase inhibitor MMI270 , 2004, Cancer science.
[96] M. Karin,et al. Inhibition of NF-kappaB in cancer cells converts inflammation- induced tumor growth mediated by TNFalpha to TRAIL-mediated tumor regression. , 2004, Cancer cell.
[97] C. López-Otín,et al. Loss of collagenase-2 confers increased skin tumor susceptibility to male mice , 2003, Nature Genetics.
[98] W. Parks,et al. Hypochlorous Acid Generated by Myeloperoxidase Modifies Adjacent Tryptophan and Glycine Residues in the Catalytic Domain of Matrix Metalloproteinase-7 (Matrilysin) , 2003, Journal of Biological Chemistry.
[99] C. Cordon-Cardo,et al. A multigenic program mediating breast cancer metastasis to bone. , 2003, Cancer cell.
[100] R. Hynes,et al. Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. , 2003, Cancer cell.
[101] Hiroshi Fukuda,et al. Tumor detection using 18F-labeled matrix metalloproteinase-2 inhibitor. , 2003, Nuclear medicine and biology.
[102] R. Hynes,et al. Physiological levels of tumstatin, a fragment of collagen IV alpha3 chain, are generated by MMP-9 proteolysis and suppress angiogenesis via alphaV beta3 integrin. , 2003, Cancer cell.
[103] William C. Parks,et al. Matrilysin Shedding of Syndecan-1 Regulates Chemokine Mobilization and Transepithelial Efflux of Neutrophils in Acute Lung Injury , 2002, Cell.
[104] J. Wallace,et al. Matrix metalloproteinase processing of monocyte chemoattractant proteins generates CC chemokine receptor antagonists with anti-inflammatory properties in vivo. , 2002, Blood.
[105] Lynda F. Bonewald,et al. Proteolysis of Latent Transforming Growth Factor-β (TGF-β)-binding Protein-1 by Osteoclasts , 2002, The Journal of Biological Chemistry.
[106] S. Rafii,et al. Recruitment of Stem and Progenitor Cells from the Bone Marrow Niche Requires MMP-9 Mediated Release of Kit-Ligand , 2002, Cell.
[107] D. Sheppard,et al. The integrin αvβ8 mediates epithelial homeostasis through MT1-MMP–dependent activation of TGF-β1 , 2002, The Journal of cell biology.
[108] Rakesh K Jain,et al. Lymphatic Metastasis in the Absence of Functional Intratumor Lymphatics , 2002, Science.
[109] B. Fingleton,et al. Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations , 2002, Science.
[110] Z. Werb,et al. New functions for the matrix metalloproteinases in cancer progression , 2002, Nature Reviews Cancer.
[111] Sarah L Dallas,et al. Proteolysis of latent transforming growth factor-beta (TGF-beta )-binding protein-1 by osteoclasts. A cellular mechanism for release of TGF-beta from bone matrix. , 2002, The Journal of biological chemistry.
[112] M. Washington,et al. Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. , 2002, The Journal of clinical investigation.
[113] Juan P. Albar,et al. Membrane Type 1-Matrix Metalloproteinase Is Activated during Migration of Human Endothelial Cells and Modulates Endothelial Motility and Matrix Remodeling* , 2001, The Journal of Biological Chemistry.
[114] R. Lijnen,et al. Inactivation of the serpin alpha(2)-antiplasmin by stromelysin-1. , 2001, Biochimica et biophysica acta.
[115] Ralph Weissleder,et al. In vivo molecular target assessment of matrix metalloproteinase inhibition , 2001, Nature Medicine.
[116] Z. Werb,et al. Stromelysin-1 Regulates Adipogenesis during Mammary Gland Involution , 2001, The Journal of cell biology.
[117] I. Stamenkovic,et al. Matrix metalloproteinase-7-mediated cleavage of Fas ligand protects tumor cells from chemotherapeutic drug cytotoxicity. , 2001, Cancer research.
[118] Z. Werb,et al. How matrix metalloproteinases regulate cell behavior. , 2001, Annual review of cell and developmental biology.
[119] P. E. Van den Steen,et al. Neutrophil gelatinase B potentiates interleukin-8 tenfold by aminoterminal processing, whereas it degrades CTAP-III, PF-4, and GRO-alpha and leaves RANTES and MCP-2 intact. , 2000, Blood.
[120] Shigeyoshi Itohara,et al. Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis , 2000, Nature Cell Biology.
[121] Z. Werb,et al. The Serpin α1-Proteinase Inhibitor Is a Critical Substrate for Gelatinase B/MMP-9 In Vivo , 2000, Cell.
[122] I. Stamenkovic,et al. Cell surface-localized matrix metalloproteinase-9 proteolytically activates TGF-beta and promotes tumor invasion and angiogenesis. , 2000, Genes & development.
[123] B. Fingleton,et al. Matrix metalloproteinase-7-dependent release of tumor necrosis factor-alpha in a model of herniated disc resorption. , 2000, The Journal of clinical investigation.
[124] D. Hanahan,et al. The Hallmarks of Cancer , 2000, Cell.
[125] J. Woessner,et al. Matrix metalloproteinases and TIMPs , 2000 .
[126] H. Dvorak,et al. The association between tumour progression and vascularity in myxofibrosarcoma and myxoid/round cell liposarcoma , 2000, Virchows Archiv.
[127] D. Pinkel,et al. The Stromal Proteinase MMP3/Stromelysin-1 Promotes Mammary Carcinogenesis , 1999, Cell.
[128] R. Pierce,et al. Matrix metalloproteinases generate angiostatin: effects on neovascularization. , 1998, Journal of immunology.
[129] A. Newby,et al. Synergistic upregulation of metalloproteinase‐9 by growth factors and inflammatory cytokines: an absolute requirement for transcription factor NF‐κB , 1998, FEBS letters.
[130] Z. Werb,et al. Matrix Metalloproteinase Stromelysin-1 Triggers a Cascade of Molecular Alterations That Leads to Stable Epithelial-to-Mesenchymal Conversion and a Premalignant Phenotype in Mammary Epithelial Cells , 1997, The Journal of cell biology.
[131] B. C. Patterson,et al. Angiostatin-converting Enzyme Activities of Human Matrilysin (MMP-7) and Gelatinase B/Type IV Collagenase (MMP-9)* , 1997, The Journal of Biological Chemistry.
[132] A. Strongin,et al. Mechanism Of Cell Surface Activation Of 72-kDa Type IV Collagenase , 1995, The Journal of Biological Chemistry.
[133] S. Weiss,et al. Oxidative autoactivation of latent collagenase by human neutrophils. , 1985, Science.
[134] L. Liotta,et al. Metastatic potential correlates with enzymatic degradation of basement membrane collagen , 1980, Nature.
[135] I. M. Neiman,et al. [Inflammation and cancer]. , 1974, Patologicheskaia fiziologiia i eksperimental'naia terapiia.
[136] C. Lapière,et al. Collagenolytic activity in amphibian tissues: a tissue culture assay. , 1962, Proceedings of the National Academy of Sciences of the United States of America.