[2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation.]

2017 ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation

[1]  Samin K. Sharma,et al.  Culprit vessel percutaneous coronary intervention versus multivessel and staged percutaneous coronary intervention for ST-segment elevation myocardial infarction patients with multivessel disease. , 2010, JACC. Cardiovascular interventions.

[2]  Ian Graham,et al.  ESC/EAS Guidelines for the management of dyslipidaemias , 2017 .

[3]  D. Chamberlain,et al.  Five hundred patients with myocardial infarction monitored within one hour of symptoms. , 1983, British medical journal.

[4]  M. Guglin,et al.  Ultrafiltration versus intravenous diuretics for patients hospitalized for acute decompensated heart failure. , 2007, Journal of the American College of Cardiology.

[5]  T. Henry,et al.  Benefit of Transferring ST-Segment–Elevation Myocardial Infarction Patients for Percutaneous Coronary Intervention Compared With Administration of Onsite Fibrinolytic Declines as Delays Increase , 2011, Circulation.

[6]  G. Lip,et al.  The HAS-BLED score has better prediction accuracy for major bleeding than CHADS2 or CHA2DS2-VASc scores in anticoagulated patients with atrial fibrillation. , 2013, Journal of the American College of Cardiology.

[7]  J. Vincent,et al.  Comparison of dopamine and norepinephrine in the treatment of shock. , 2010, The New England journal of medicine.

[8]  R. West,et al.  Impact of hospital proportion and volume on primary percutaneous coronary intervention performance in England and Wales. , 2011, European heart journal.

[9]  F. Fernández‐Avilés,et al.  Consistency of benefit from an early invasive strategy after fibrinolysis: a patient-level meta-analysis , 2015, Heart.

[10]  R. Collins,et al.  Efficacy and safety of cholesterol-lowering treatment: prospective meta-analysis of data from 90 056 participants in 14 randomised trials of statins , 2005, The Lancet.

[11]  A. Lincoff,et al.  Magnitude and consequences of missing the acute infarct-related circumflex artery. , 2009, American heart journal.

[12]  R Dietz,et al.  Effects of controlled-release metoprolol on total mortality, hospitalizations, and well-being in patients with heart failure: the Metoprolol CR/XL Randomized Intervention Trial in congestive heart failure (MERIT-HF). MERIT-HF Study Group. , 2000, JAMA.

[13]  G. Wagner,et al.  Early electrocardiographic diagnosis of acute myocardial infarction in the presence of ventricular paced rhythm. GUSTO-I investigators. , 1996, The American journal of cardiology.

[14]  Volkmar Falk,et al.  2016 ESC Guidelines for the Diagnosis and Treatment of Acute and Chronic Heart Failure. , 2016, Revista espanola de cardiologia.

[15]  W Klein,et al.  Management of acute coronary syndromes. Variations in practice and outcome; findings from the Global Registry of Acute Coronary Events (GRACE). , 2002, European heart journal.

[16]  E. Veys,et al.  HL-A AND INFECTIVE SACROILEITIS , 1974 .

[17]  K. Harjai,et al.  Effects of prior beta-blocker therapy on clinical outcomes after primary coronary angioplasty for acute myocardial infarction. , 2003, The American journal of cardiology.

[18]  P. Ridker,et al.  Very low levels of atherogenic lipoproteins and the risk for cardiovascular events: a meta-analysis of statin trials. , 2014, Journal of the American College of Cardiology.

[19]  G. Stone,et al.  Bivalirudin vs heparin with or without tirofiban during primary percutaneous coronary intervention in acute myocardial infarction: the BRIGHT randomized clinical trial. , 2015, JAMA.

[20]  Ross T Tsuyuki,et al.  A meta-analysis of the association between adherence to drug therapy and mortality , 2006, BMJ : British Medical Journal.

[21]  D. Yuh,et al.  Optimal timing of coronary artery bypass after acute myocardial infarction: a review of California discharge data. , 2008, The Journal of thoracic and cardiovascular surgery.

[22]  J. McMurray,et al.  Eplerenone in patients with systolic heart failure and mild symptoms. , 2011, The New England journal of medicine.

[23]  C. Furberg,et al.  Calcium channel blockers in acute myocardial infarction and unstable angina: an overview. , 1989, BMJ.

[24]  Barry J. Davis,et al.  Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174 000 participants in 27 randomised trials , 2015, The Lancet.

[25]  V. Hasselblad,et al.  Time-based risk assessment after myocardial infarction. Implications for timing of discharge and applications to medical decision-making. , 2003, European heart journal.

[26]  David Erlinge,et al.  Thrombus aspiration during ST-segment elevation myocardial infarction. , 2013, The New England journal of medicine.

[27]  Armando Pérez de Prado,et al.  Role of the Paclitaxel-Eluting Stent and Tirofiban in Patients With ST-Elevation Myocardial Infarction Undergoing Postfibrinolysis Angioplasty: The GRACIA-3 Randomized Clinical Trial , 2010, Circulation. Cardiovascular interventions.

[28]  G. Stone,et al.  Correlation between index electrocardiographic patterns and pre‐intervention angiographic findings: Insights from the HORIZONS‐AMI trial , 2012, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[29]  D. Wade,et al.  Cognitive impairments in survivors of out-of-hospital cardiac arrest: a systematic review. , 2009, Resuscitation.

[30]  André Lamy,et al.  F-18-fluorodeoxyglucose positron emission tomography imaging-assisted management of patients with severe left ventricular dysfunction and suspected coronary disease: a randomized, controlled trial (PARR-2). , 2007, Journal of the American College of Cardiology.

[31]  A. Shrivastava,et al.  Serial measurement of lipid profile and inflammatory markers in patients with acute myocardial infarction , 2015, EXCLI journal.

[32]  N. Deshpande,et al.  Prasugrel versus clopidogrel for acute coronary syndromes without revascularization , 2013 .

[33]  Gavin D Perkins,et al.  European Resuscitation Council Guidelines for Resuscitation 2015: Section 1. Executive summary. , 2015, Resuscitation.

[34]  Relationship between time to invasive assessment and clinical outcomes of patients undergoing an early invasive strategy after fibrinolysis for ST-segment elevation myocardial infarction: a patient-level analysis of the randomized early routine invasive clinical trials. , 2015, JACC. Cardiovascular interventions.

[35]  P. Armstrong,et al.  Incidence of and outcomes associated with ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention. , 2009, JAMA.

[36]  M. Zembala,et al.  Reperfusion by primary percutaneous coronary intervention in patients with ST-segment elevation myocardial infarction within 12 to 24 hours of the onset of symptoms (from a prospective national observational study [PL-ACS]). , 2011, The American journal of cardiology.

[37]  Assent investigators.  Efficacy and safety of tenecteplase in combination with enoxaparin, abciximab, or unfractionated heparin: the ASSENT-3 randomised trial in acute myocardial infarction , 2001, The Lancet.

[38]  E. Bonnefoy,et al.  WITHDRAWN: Primary angioplasty versus intravenous thrombolysis for acute myocardial infarction. , 2007, The Cochrane database of systematic reviews.

[39]  R. Dreyer,et al.  Systematic Review of Patients Presenting With Suspected Myocardial Infarction and Nonobstructive Coronary Arteries , 2015, Circulation.

[40]  P. Serruys,et al.  Biodegradable polymer drug-eluting stents reduce the risk of stent thrombosis at 4 years in patients undergoing percutaneous coronary intervention: a pooled analysis of individual patient data from the ISAR-TEST 3, ISAR-TEST 4, and LEADERS randomized trials. , 2012, European heart journal.

[41]  C. Furberg,et al.  Update of effects of calcium antagonists in myocardial infarction or angina in light of the second Danish Verapamil Infarction Trial (DAVIT-II) and other recent studies. , 1991, The American journal of cardiology.

[42]  Baris Gencer,et al.  ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation , 2011 .

[43]  H. Bøtker,et al.  Quality indicators for acute myocardial infarction: A position paper of the Acute Cardiovascular Care Association , 2017, European heart journal. Acute cardiovascular care.

[44]  Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril. , 1994, Circulation.

[45]  K. Werdan,et al.  Intra-aortic balloon counterpulsation in the treatment of infarction-related cardiogenic shock--review of the current evidence. , 2012, Artificial organs.

[46]  R. Collins,et al.  Indications for ACE inhibitors in the early treatment of acute myocardial infarction: systematic overview of individual data from 100,000 patients in randomized trials. ACE Inhibitor Myocardial Infarction Collaborative Group. , 1998, Circulation.

[47]  A. Kastrati,et al.  Mechanical reperfusion and long-term mortality in patients with acute myocardial infarction presenting 12 to 48 hours from onset of symptoms. , 2009, JAMA.

[48]  Braunwald,et al.  Twelve or 30 months of dual antiplatelet therapy after drug-eluting stents. , 2014, The New England journal of medicine.

[49]  R. O’Connor,et al.  Part 5: Acute Coronary Syndromes 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science With Treatment Recommendations , 2015 .

[50]  Raúl Moreno,et al.  Revascularización de lesiones no culpables en el IAMCEST: que se COMPLETE la evidencia , 2017 .

[51]  S. Bernard,et al.  Treatment of comatose survivors of out-of-hospital cardiac arrest with induced hypothermia. , 2002, The New England journal of medicine.

[52]  V. Gebski,et al.  Immediate Postoperative Aspirin Improves Vein Graft Patency Early and Late After Coronary Artery Bypass Graft Surgery: A Placebo‐Controlled, Randomized Study , 1991, Circulation.

[53]  D. Doyle,et al.  Comparison of high-dose with low-dose subcutaneous heparin to prevent left ventricular mural thrombosis in patients with acute transmural anterior myocardial infarction. , 1989, The New England journal of medicine.

[54]  C. Zeng,et al.  Efficiency and Safety of Proprotein Convertase Subtilisin/Kexin 9 Monoclonal Antibody on Hypercholesterolemia: A Meta-Analysis of 20 Randomized Controlled Trials , 2015, Journal of the American Heart Association.

[55]  H. White,et al.  Echocardiographic Predictors of Survival and Response to Early Revascularization in Cardiogenic Shock , 2003, Circulation.

[56]  B. Gersh.  Comparison of Thrombolysis Followed by Broad Use of Percutaneous Coronary Intervention with Primary Percutaneous Coronary Intervention for ST-Segment–Elevation Acute Myocardial Infarction: Data From the French Registry on Acute ST-Elevation Myocardial Infarction (FAST-MI) , 2009 .

[57]  H. Bøtker,et al.  Infarct size and myocardial salvage after primary angioplasty in patients presenting with symptoms for <12 h vs. 12-72 h. , 2009, European heart journal.

[58]  M. Posch,et al.  Morphine decreases clopidogrel concentrations and effects: a randomized, double-blind, placebo-controlled trial. , 2014, Journal of the American College of Cardiology.

[59]  Andrea Mazzanti,et al.  [2015 ESC Guidelines for the management of patients with ventricular arrhythmias and the prevention of sudden cardiac death]. , 2015, Kardiologia polska.

[60]  G Barbash,et al.  Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trial. , 1999, Lancet.

[61]  R. O’Connor,et al.  Part 5: Acute coronary syndromes: 2015 International Consensus on Cardiopulmonary Resuscitation and Emergency Cardiovascular Care Science with Treatment Recommendations. , 2015, Resuscitation.

[62]  Fibrinolytictherapytrialistsf.  Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients , 1994 .

[63]  J. Rawles,et al.  Controlled trial of oxygen in uncomplicated myocardial infarction. , 1976, British medical journal.

[64]  K. Sagar,et al.  Dobutamine stress echocardiography for risk stratification after myocardial infarction. , 1997, Circulation.

[65]  P. Serruys,et al.  Everolimus-eluting stent versus bare-metal stent in ST-segment elevation myocardial infarction (EXAMINATION): 1 year results of a randomised controlled trial , 2012, The Lancet.

[66]  P. Lesault,et al.  Six-Month Outcome of Emergency Percutaneous Coronary Intervention in Resuscitated Patients After Cardiac Arrest Complicating ST-Elevation Myocardial Infarction , 2007, Circulation.

[67]  P. Serruys,et al.  Clinical outcomes in patients with ST-segment elevation myocardial infarction treated with everolimus-eluting stents versus bare-metal stents (EXAMINATION): 5-year results of a randomised trial , 2016, The Lancet.

[68]  Sunil V. Rao,et al.  Outcomes after thrombus aspiration for ST elevation myocardial infarction: 1-year follow-up of the prospective randomised TOTAL trial , 2016, The Lancet.

[69]  H. Schunkert,et al.  Prasugrel plus bivalirudin vs. clopidogrel plus heparin in patients with ST-segment elevation myocardial infarction. , 2014, European heart journal.

[70]  J. J. Griffin,et al.  Comparison of angioplasty with stenting, with or without abciximab, in acute myocardial infarction. , 2002, The New England journal of medicine.

[71]  S. Pocock,et al.  to improve adherence : results from FOCUS ( Fixed-dose Combination Drug for Secondary Cardiovascular Prevention ) Project , 2014 .

[72]  H. Schuchlenz,et al.  Clopidogrel pre-treatment is associated with reduced in-hospital mortality in primary percutaneous coronary intervention for acute ST-elevation myocardial infarction. , 2011, European heart journal.

[73]  L. Svensson,et al.  DETermination of the role of OXygen in suspected Acute Myocardial Infarction trial. , 2014, American heart journal.

[74]  G. Lamas,et al.  Coronary intervention for persistent occlusion after myocardial infarction. , 2006, The New England journal of medicine.

[75]  F. Carre,et al.  Secondary prevention through cardiac rehabilitation: physical activity counselling and exercise training: key components of the position paper from the Cardiac Rehabilitation Section of the European Association of Cardiovascular Prevention and Rehabilitation. , 2010, European heart journal.

[76]  M. Chang,et al.  Acute treatment of recent-onset atrial fibrillation and flutter with a tailored dosing regimen of intravenous amiodarone. A randomized, digoxin-controlled study. , 1995, European heart journal.

[77]  A. Parkhomenko,et al.  Enoxaparin is superior to unfractionated heparin in patients with ST elevation myocardial infarction undergoing fibrinolysis regardless of the choice of lytic: an ExTRACT-TIMI 25 analysis. , 2007, European heart journal.

[78]  Edo Kaluski,et al.  ST-Segment Analysis Using Wireless Technology in Acute Myocardial Infarction (STAT-MI) trial. , 2007, Journal of the American College of Cardiology.

[79]  T. Ikeda,et al.  Effects of landiolol, an ultra-short-acting beta1-selective blocker, on electrical storm refractory to class III antiarrhythmic drugs. , 2010, Circulation journal : official journal of the Japanese Circulation Society.

[80]  P. Armstrong,et al.  Early routine percutaneous coronary intervention after fibrinolysis vs. standard therapy in ST-segment elevation myocardial infarction: a meta-analysis. , 2010, European heart journal.

[81]  Deepak L. Bhatt,et al.  Intravenous platelet blockade with cangrelor during PCI. , 2009, The New England journal of medicine.

[82]  M. Gnant,et al.  Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials , 2010 .

[83]  M. Jeong,et al.  Sex differences in management and mortality of patients with ST-elevation myocardial infarction (from the Korean Acute Myocardial Infarction National Registry). , 2012, The American journal of cardiology.

[84]  Eric Boersma,et al.  Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hour , 1996, The Lancet.

[85]  A. Camm,et al.  Cardiac arrhythmias in acute coronary syndromes: position paper from the joint EHRA, ACCA, and EAPCI task force. , 2015, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[86]  M. Aschermann,et al.  Long distance transport for primary angioplasty vs immediate thrombolysis in acute myocardial infarction. Final results of the randomized national multicentre trial--PRAGUE-2. , 2003, European heart journal.

[87]  S. Hohnloser,et al.  Atrial fibrillation in acute myocardial infarction: a systematic review of the incidence, clinical features and prognostic implications. , 2009, European heart journal.

[88]  C. Hofer,et al.  Beneficial effects of immediate stenting after thrombolysis in acute myocardial infarction. , 2003, Journal of the American College of Cardiology.

[89]  S. Windecker,et al.  Bivalirudin or unfractionated heparin in patients with acute coronary syndromes managed invasively with and without ST elevation (MATRIX): randomised controlled trial , 2016, British Medical Journal.

[90]  S. Windecker,et al.  Impact of proton pump inhibitors on clinical outcomes in patients treated with a 6- or 24-month dual-antiplatelet therapy duration: Insights from the PROlonging Dual-antiplatelet treatment after Grading stent-induced Intimal hyperplasia studY trial. , 2016, American heart journal.

[91]  S. Pocock,et al.  Bivalirudin started during emergency transport for primary PCI. , 2013, The New England journal of medicine.

[92]  ICHAEL,et al.  THE EFFECT OF CARVEDILOL ON MORBIDITY AND MORTALITY IN PATIENTS WITH CHRONIC HEART FAILURE , 2000 .

[93]  M. Cooper,et al.  Rapid loading of sotalol or amiodarone for management of recent onset symptomatic atrial fibrillation: a randomized, digoxin-controlled trial. , 2004, American heart journal.

[94]  E. Aliot,et al.  A clinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. Trandolapril Cardiac Evaluation (TRACE) Study Group. , 1995, The New England journal of medicine.

[95]  S. Solomon,et al.  Early versus delayed angiotensin-converting enzyme inhibition therapy in acute myocardial infarction. The healing and early afterload reducing therapy trial. , 1997, Circulation.

[96]  P. Aegerter,et al.  Efficacy of therapeutic hypothermia after out-of-hospital cardiac arrest due to ventricular fibrillation. , 2007, Resuscitation.

[97]  S. Antoniou,et al.  Safety and feasibility of hospital discharge 2 days following primary percutaneous intervention for ST-segment elevation myocardial infarction , 2012, Heart.

[98]  Rod S Taylor,et al.  Exercise-Based Cardiac Rehabilitation for Coronary Heart Disease: Cochrane Systematic Review and Meta-Analysis. , 2016, Journal of the American College of Cardiology.

[99]  H. Swanton,et al.  Randomized Trial of Complete Versus Lesion-Only Revascularization in Patients Undergoing Primary Percutaneous Coronary Intervention for STEMI and Multivessel Disease , 2015, Journal of the American College of Cardiology.

[100]  Gregg W Stone,et al.  Platelet inhibition with cangrelor in patients undergoing PCI. , 2009, The New England journal of medicine.

[101]  J. Le Heuzey,et al.  Impact of early statin therapy on development of atrial fibrillation at the acute stage of myocardial infarction: data from the FAST-MI register , 2010, Heart.

[102]  G. Filippatos,et al.  Contemporary management of acute right ventricular failure: a statement from the Heart Failure Association and the Working Group on Pulmonary Circulation and Right Ventricular Function of the European Society of Cardiology , 2016, European journal of heart failure.

[103]  L. Køber,et al.  Risk of bleeding in patients with acute myocardial infarction treated with different combinations of aspirin, clopidogrel, and vitamin K antagonists in Denmark: a retrospective analysis of nationwide registry data , 2009, The Lancet.

[104]  J. Tijssen,et al.  Incremental Value of the CRUSADE, ACUITY, and HAS‐BLED Risk Scores for the Prediction of Hemorrhagic Events After Coronary Stent Implantation in Patients Undergoing Long or Short Duration of Dual Antiplatelet Therapy , 2015, Journal of the American Heart Association.

[105]  E. Vicaut,et al.  Intravenous enoxaparin or unfractionated heparin in primary percutaneous coronary intervention for ST-elevation myocardial infarction: the international randomised open-label ATOLL trial , 2011, The Lancet.

[106]  R. Califf,et al.  Atrial fibrillation management strategies and early mortality after myocardial infarction: results from the Valsartan in Acute Myocardial Infarction (VALIANT) Trial , 2010, Heart.

[107]  C. Berry,et al.  A Randomized Trial of Deferred Stenting Versus Immediate Stenting to Prevent No- or Slow-Reflow in Acute ST-Segment Elevation Myocardial Infarction (DEFER-STEMI) , 2014, Journal of the American College of Cardiology.

[108]  J. McMurray,et al.  Clinical benefits of eplerenone in patients with systolic heart failure and mild symptoms when initiated shortly after hospital discharge: analysis from the EMPHASIS-HF trial. , 2015, European heart journal.

[109]  S. Halvorsen,et al.  Efficacy and safety of immediate angioplasty versus ischemia-guided management after thrombolysis in acute myocardial infarction in areas with very long transfer distances results of the NORDISTEMI (NORwegian study on DIstrict treatment of ST-elevation myocardial infarction). , 2010, Journal of the American College of Cardiology.

[110]  C. Callaway,et al.  Duration of Resuscitation Efforts and Functional Outcome After Out-of-Hospital Cardiac Arrest: When Should We Change to Novel Therapies? , 2013, Circulation.

[111]  J. Ottervanger,et al.  Long-term benefit of primary angioplasty compared to thrombolytic therapy for acute myocardial infarction. , 2000, European heart journal.

[112]  O. Alfieri,et al.  Sensitivity, specificity, and predictive accuracies of non-invasive tests, singly and in combination, for diagnosis of hibernating myocardium. , 2000, European heart journal.

[113]  Jennifer G. Robinson,et al.  Efficacy and safety of alirocumab in reducing lipids and cardiovascular events. , 2015, The New England journal of medicine.

[114]  B. Gersh.  Facilitated PCI in Patients with ST-Elevation Myocardial Infarction , 2009 .

[115]  S. Behar,et al.  Use of intravenous morphine for acute decompensated heart failure in patients with and without acute coronary syndromes , 2011, Acute cardiac care.

[116]  A. Shimony,et al.  Meta-analysis of randomized controlled trials of intracoronary versus intravenous administration of glycoprotein IIb/IIIa inhibitors during percutaneous coronary intervention for acute coronary syndrome. , 2011, The American journal of cardiology.

[117]  Maarten L. Simoons,et al.  The third universal definition of myocardial infarction , 2013 .

[118]  J. J. Griffin,et al.  Impact of intravenous beta-blockade before primary angioplasty on survival in patients undergoing mechanical reperfusion therapy for acute myocardial infarction. , 2004, Journal of the American College of Cardiology.

[119]  H. Snooks,et al.  Effects of prehospital 12-lead ECG on processes of care and mortality in acute coronary syndrome: a linked cohort study from the Myocardial Ischaemia National Audit Project , 2014, Heart.

[120]  J. R. Carmona,et al.  Primary angioplasty vs. fibrinolysis in very old patients with acute myocardial infarction: TRIANA (TRatamiento del Infarto Agudo de miocardio eN Ancianos) randomized trial and pooled analysis with previous studies , 2010, European heart journal.

[121]  R. Collins,et al.  Aspirin in the primary and secondary prevention of vascular disease: collaborative meta-analysis of individual participant data from randomised trials , 2009, The Lancet.

[122]  J. Ioannidis,et al.  Percutaneous coronary intervention for late reperfusion after myocardial infarction in stable patients. , 2007, American heart journal.

[123]  L. Køber,et al.  Complete revascularisation versus treatment of the culprit lesion only in patients with ST-segment elevation myocardial infarction and multivessel disease (DANAMI-3—PRIMULTI): an open-label, randomised controlled trial , 2015, The Lancet.

[124]  J. Oss,et al.  PROPHYLACTIC IMPLANTATION OF A DEFIBRILLATOR IN PATIENTS WITH MYOCARDIAL INFARCTION AND REDUCED EJECTION FRACTION , 2002 .

[125]  A. Chang,et al.  Lack of association between left bundle-branch block and acute myocardial infarction in symptomatic ED patients. , 2009, The American journal of emergency medicine.

[126]  A. Zafari,et al.  A program encouraging early defibrillation results in improved in-hospital resuscitation efficacy. , 2004, Journal of the American College of Cardiology.

[127]  P. Steg,et al.  Bypassing the emergency room reduces delays and mortality in ST elevation myocardial infarction: the USIC 2000 registry , 2006, Heart.

[128]  H. White,et al.  One-year survival following early revascularization for cardiogenic shock. , 2001, JAMA.

[129]  K. Kreitner,et al.  Cardiac MR enables diagnosis in 90% of patients with acute chest pain, elevated biomarkers and unobstructed coronary arteries. , 2015, The British journal of radiology.

[130]  J. F. Hansen,et al.  Effect of verapamil on mortality and major events after acute myocardial infarction (the Danish Verapamil Infarction Trial II--DAVIT II) , 1990, The American journal of cardiology.

[131]  E. Ruokonen,et al.  Therapeutic hypothermia after out-of-hospital cardiac arrest in Finnish intensive care units: the FINNRESUSCI study , 2013, Intensive Care Medicine.

[132]  Gregg W Stone,et al.  Effect of platelet inhibition with cangrelor during PCI on ischemic events. , 2013, The New England journal of medicine.

[133]  K. Huber,et al.  Efficacy and safety of a high loading dose of clopidogrel administered prehospitally to improve primary percutaneous coronary intervention in acute myocardial infarction: the randomized CIPAMI trial , 2012, Clinical Research in Cardiology.

[134]  F. Fernández‐Avilés,et al.  Primary angioplasty vs. early routine post-fibrinolysis angioplasty for acute myocardial infarction with ST-segment elevation: the GRACIA-2 non-inferiority, randomized, controlled trial. , 2007, European heart journal.

[135]  Quan-ying He,et al.  Meta-analysis: Noninvasive Ventilation in Acute Cardiogenic Pulmonary Edema , 2010, Annals of Internal Medicine.

[136]  Peter Cameron,et al.  Air Versus Oxygen in ST-Segment–Elevation Myocardial Infarction , 2015, Circulation.

[137]  P. Kudenchuk,et al.  Effect of Prehospital Induction of Mild Hypothermia on Survival and Neurological Status Among Adults With Cardiac Arrest: A Randomized Clinical Trial , 2014 .

[138]  V. Fuster,et al.  A polypill strategy to improve global secondary cardiovascular prevention: from concept to reality. , 2014, Journal of the American College of Cardiology.

[139]  E. Antman,et al.  TIMI Risk Score for ST-Elevation Myocardial Infarction: A Convenient, Bedside, Clinical Score for Risk Assessment at Presentation: An Intravenous nPA for Treatment of Infarcting Myocardium Early II Trial Substudy , 2000, Circulation.

[140]  S. Yusuf,et al.  Thrombus Aspiration in ST Elevation Myocardial Infarction : An Individual Patient Meta-analysis Running , 2016 .

[141]  S. Yusuf,et al.  Double-dose versus standard-dose clopidogrel and high-dose versus low-dose aspirin in individuals undergoing percutaneous coronary intervention for acute coronary syndromes (CURRENT-OASIS 7): a randomised factorial trial , 2010, The Lancet.

[142]  C. Gale,et al.  Comparison of Early Versus Delayed Oral β Blockers in Acute Coronary Syndromes and Effect on Outcomes. , 2016, The American journal of cardiology.

[143]  A. Budaj,et al.  Relationship of ST elevation in lead aVR with angiographic findings and outcome in non-ST elevation acute coronary syndromes. , 2007, American heart journal.

[144]  J. Fontanals,et al.  Hypothermia in acute coronary syndrome: brain salvage versus stent thrombosis? , 2013, Journal of the American College of Cardiology.

[145]  A. Zaman,et al.  Early discharge after primary percutaneous coronary intervention for ST-elevation myocardial infarction , 2013, European heart journal. Acute cardiovascular care.

[146]  I. Piña.  Valsartan in acute myocardial infarction trial. , 2004, Current cardiology reports.

[147]  L. Newby,et al.  Incidence, distribution, and prognostic impact of occluded culprit arteries among patients with non-ST-elevation acute coronary syndromes undergoing diagnostic angiography. , 2009, American heart journal.

[148]  Shigeru Nakamura,et al.  Catheter ablation of fatal ventricular tachyarrhythmias storm in acute coronary syndrome—role of Purkinje fiber network , 2009, Journal of interventional cardiac electrophysiology.

[149]  Harlan M Krumholz,et al.  Relation between door-to-balloon times and mortality after primary percutaneous coronary intervention over time: a retrospective study , 2015, The Lancet.

[150]  P. Armstrong,et al.  Temporal trends in patient and treatment delay among men and women presenting with ST-elevation myocardial infarction. , 2011, American heart journal.

[151]  N Freemantle,et al.  beta Blockade after myocardial infarction: systematic review and meta regression analysis. , 1999, BMJ.

[152]  I. Komuro,et al.  Clinical Impact of Ventricular Tachycardia and/or Fibrillation During the Acute Phase of Acute Myocardial Infarction on In-Hospital and 5-Year Mortality Rates in the Percutaneous Coronary Intervention Era. , 2016, Circulation Journal.

[153]  H. Krumholz,et al.  Association of door-in to door-out time with reperfusion delays and outcomes among patients transferred for primary percutaneous coronary intervention. , 2011, JAMA.

[154]  K. Eagle,et al.  Prediction of risk of death and myocardial infarction in the six months after presentation with acute coronary syndrome: prospective multinational observational study (GRACE) , 2006, BMJ : British Medical Journal.

[155]  S. Nekolla,et al.  Mechanical Reperfusion in Patients With Acute Myocardial Infarction Presenting More Than 12 Hours From Symptom Onset: A Randomized Controlled Trial , 2005 .

[156]  M. Pfisterer,et al.  Hemodynamic parameters are prognostically important in cardiogenic shock but similar following early revascularization or initial medical stabilization: a report from the SHOCK Trial. , 2007, Chest.

[157]  N. Laird,et al.  Meta-analytic evidence against prophylactic use of lidocaine in acute myocardial infarction. , 1989, Archives of internal medicine.

[158]  D. Jacobs,et al.  Relation of length of hospital stay in acute myocardial infarction to postdischarge mortality. , 2008, The American journal of cardiology.

[159]  M. Mamas,et al.  Routine early coronary angioplasty versus ischaemia-guided angioplasty after thrombolysis in acute ST-elevation myocardial infarction: a meta-analysis. , 2011, European heart journal.

[160]  E. Ohman,et al.  Relationship Between Infarct Size and Outcomes Following Primary PCI: Patient-Level Analysis From 10 Randomized Trials. , 2016, Journal of the American College of Cardiology.

[161]  K. Schenck-Gustafsson,et al.  Gender in cardiovascular diseases: impact on clinical manifestations, management, and outcomes. , 2016, European heart journal.

[162]  A. Cohen-Solal,et al.  Randomized trial to determine the effect of nebivolol on mortality and cardiovascular hospital admission in elderly patients with heart failure (SENIORS). , 2005, European heart journal.

[163]  L. Wallentin,et al.  Relation between renal function, presentation, use of therapies and in‐hospital complications in acute coronary syndrome: data from the SWEDEHEART register , 2010, Journal of internal medicine.

[164]  J. Tijssen,et al.  Percutaneous Mechanical Circulatory Support Versus Intra-Aortic Balloon Pump in Cardiogenic Shock After Acute Myocardial Infarction. , 2017, Journal of the American College of Cardiology.

[165]  E. Peterson,et al.  Timing of First Postdischarge Follow-up and Medication Adherence After Acute Myocardial Infarction. , 2016, JAMA cardiology.

[166]  S. Ebrahim,et al.  Exercise-based rehabilitation for patients with coronary heart disease: systematic review and meta-analysis of randomized controlled trials. , 2004, The American journal of medicine.

[167]  J. Bronzwaer,et al.  Improved clinical outcome after invasive management of patients with recent myocardial infarction and proven myocardial viability: primary results of a randomized controlled trial (VIAMI-trial) , 2012, Trials.

[168]  A. Keech,et al.  Evolocumab and Clinical Outcomes in Patients with Cardiovascular Disease , 2017, The New England journal of medicine.

[169]  Per Albertsson,et al.  Population trends in percutaneous coronary intervention: 20-year results from the SCAAR (Swedish Coronary Angiography and Angioplasty Registry). , 2013, Journal of the American College of Cardiology.

[170]  G. Murray,et al.  Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators , 1993 .

[171]  Deepak L. Bhatt,et al.  Complete or Culprit-Only Revascularization for Patients With Multivessel Coronary Artery Disease Undergoing Percutaneous Coronary Intervention: A Pairwise and Network Meta-Analysis of Randomized Trials. , 2017, JACC. Cardiovascular interventions.

[172]  M. Munafo,et al.  Interventions for smoking cessation in hospitalised patients. , 2003, The Cochrane database of systematic reviews.

[173]  B. Pitt,et al.  EPLERENONE POST-ACUTE MYOCARDIAL INFARCTION HEART FAILURE EFFICACY AND SURVIVAL STUDY INVESTIGATORS. EPLERENONE, A SELECTIVE ALDOSTERONE BLOCKER, IN PATIENTS WITH LEFT VENTRICULAR DYSFUNCTION AFTER MYOCARDIAL INFARCTION , 2003 .

[174]  R. Luepker,et al.  Gender disparity in cardiac procedures and medication use for acute myocardial infarction. , 2008, American heart journal.

[175]  S. Dixon,et al.  A multicentre randomised controlled trial of the use of continuous positive airway pressure and non-invasive positive pressure ventilation in the early treatment of patients presenting to the emergency department with severe acute cardiogenic pulmonary oedema: the 3CPO trial. , 2009, Health technology assessment.

[176]  Y. Rosenberg,et al.  Effect of Beta-Blocker Dose on Survival After Acute Myocardial Infarction. , 2015, Journal of the American College of Cardiology.

[177]  M. Haissaguerre,et al.  Ventricular arrhythmias and the His–Purkinje system , 2016, Nature Reviews Cardiology.

[178]  Deepak L. Bhatt,et al.  Short- versus long-term dual antiplatelet therapy after drug-eluting stent implantation: an individual patient data pairwise and network meta-analysis. , 2015, Journal of the American College of Cardiology.

[179]  P. Armstrong,et al.  Fibrinolysis or primary PCI in ST-segment elevation myocardial infarction. , 2013, New England Journal of Medicine.

[180]  D. Roberts,et al.  The ability to achieve complete revascularization is associated with improved in‐hospital survival in cardiogenic shock due to myocardial infarction: Manitoba cardiogenic shock registry investigators , 2011, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[181]  M. Wise,et al.  Targeted temperature management at 33°C versus 36°C after cardiac arrest. , 2013, The New England journal of medicine.

[182]  P. Armstrong,et al.  ST–Segment-Elevation Myocardial Infarction Patients Randomized to a Pharmaco-Invasive Strategy or Primary Percutaneous Coronary Intervention: Strategic Reperfusion Early After Myocardial Infarction (STREAM) 1-Year Mortality Follow-Up , 2014, Circulation.

[183]  M. Pfeffer,et al.  Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both , 2004 .

[184]  V. Fuster,et al.  Long-term benefit of early pre-reperfusion metoprolol administration in patients with acute myocardial infarction: results from the METOCARD-CNIC trial (Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction). , 2014, Journal of the American College of Cardiology.

[185]  N. Powe,et al.  The association between hospital volume and survival after acute myocardial infarction in elderly patients. , 1999, The New England journal of medicine.

[186]  S. Yusuf,et al.  Blood-Pressure Lowering in Intermediate-Risk Persons without Cardiovascular Disease. , 2016, The New England journal of medicine.

[187]  H. White,et al.  Thrombin-specific anticoagulation with bivalirudin versus heparin in patients receiving fibrinolytic therapy for acute myocardial infarction: the HERO-2 randomised trial , 2001, The Lancet.

[188]  X. Jouven,et al.  Immediate Percutaneous Coronary Intervention Is Associated With Better Survival After Out-of-Hospital Cardiac Arrest: Insights From the PROCAT (Parisian Region Out of Hospital Cardiac Arrest) Registry , 2010, Circulation. Cardiovascular interventions.

[189]  M. Sabatine,et al.  Bivalirudin versus heparin in patients planned for percutaneous coronary intervention: a meta-analysis of randomised controlled trials , 2014, The Lancet.

[190]  E. Kline-Rogers,et al.  The predictive ability of the CHADS2 and CHA2DS2-VASc scores for bleeding risk in atrial fibrillation: the MAQI(2) experience. , 2014, Thrombosis research.

[191]  D. Prabhakaran,et al.  Effects of a fixed-dose combination strategy on adherence and risk factors in patients with or at high risk of CVD: the UMPIRE randomized clinical trial. , 2013, JAMA.

[192]  L. Morrison,et al.  Routine early angioplasty after fibrinolysis for acute myocardial infarction. , 2009, The New England journal of medicine.

[193]  M. Masotti,et al.  Comparison of mortality rates in acute myocardial infarction treated by percutaneous coronary intervention versus fibrinolysis. , 2005, The American journal of cardiology.

[194]  D. Altman,et al.  Indirect comparison meta-analysis of aspirin therapy after coronary surgery , 2003, BMJ : British Medical Journal.

[195]  X. Jouven,et al.  Immediate Percutaneous Coronary Intervention Is Associated With Better Survival After Out-of-Hospital Cardiac ArrestClinical Perspective , 2010 .

[196]  K. Lee,et al.  Atenolol use and clinical outcomes after thrombolysis for acute myocardial infarction: the GUSTO-I experience. Global Utilization of Streptokinase and TPA (alteplase) for Occluded Coronary Arteries. , 1998, Journal of the American College of Cardiology.

[197]  C. Hassager,et al.  Repeated echocardiography after first ever ST-segment elevation myocardial infarction treated with primary percutaneous coronary intervention – is it necessary? , 2015, European heart journal. Acute cardiovascular care.

[198]  A. Íñiguez,et al.  Effect of Early Metoprolol on Infarct Size in ST-Segment–Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention: The Effect of Metoprolol in Cardioprotection During an Acute Myocardial Infarction (METOCARD-CNIC) Trial , 2013, Circulation.

[199]  K. Fox,et al.  Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study) , 2003, The Lancet.

[200]  E. Peterson,et al.  CorrespondenceResearch CorrespondenceAnatomic Distribution of the Culprit Lesion in Patients With Non–ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Intervention: Findings From the National Cardiovascular Data Registry , 2008 .

[201]  G. Niccoli,et al.  Acute myocardial infarction with no obstructive coronary atherosclerosis: mechanisms and management. , 2015, European heart journal.

[202]  P. Sobotka,et al.  Ultrafiltration is associated with fewer rehospitalizations than continuous diuretic infusion in patients with decompensated heart failure: results from UNLOAD. , 2010, Journal of cardiac failure.

[203]  C. Cannon,et al.  Characterization of dyspnoea in PLATO study patients treated with ticagrelor or clopidogrel and its association with clinical outcomes. , 2011, European heart journal.

[204]  Frans Van de Werf,et al.  An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. , 1993, The New England journal of medicine.

[205]  Claes Held,et al.  Ticagrelor versus clopidogrel in patients with acute coronary syndromes. , 2009, The New England journal of medicine.

[206]  Deepak L. Bhatt,et al.  β-Blocker use and clinical outcomes in stable outpatients with and without coronary artery disease. , 2012, JAMA.

[207]  V. Beral,et al.  Body-mass index and all-cause mortality: individual-participant-data meta-analysis of 239 prospective studies in four continents , 2016, The Lancet.

[208]  E. Antman,et al.  Prasugrel versus clopidogrel in patients with acute coronary syndromes. , 2007, The New England journal of medicine.

[209]  E. Vicaut,et al.  A direct comparison of intravenous enoxaparin with unfractionated heparin in primary percutaneous coronary intervention (from the ATOLL trial). , 2013, The American journal of cardiology.

[210]  Fibrinolytic Therapy Trialists' Collaborative Group.  Indications for fibrinolytic therapy in suspected acute myocardial infarction: collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients , 1994, The Lancet.

[211]  Christina Lindahl,et al.  Total cardiovascular disease burden: comparing intensive with moderate statin therapy insights from the IDEAL (Incremental Decrease in End Points Through Aggressive Lipid Lowering) trial. , 2009, Journal of the American College of Cardiology.

[212]  V. Fuster,et al.  Early intravenous beta-blockers in patients with acute coronary syndrome--a meta-analysis of randomized trials. , 2013, International journal of cardiology.

[213]  CIBIS-II Investigators and Committees.  The Cardiac Insufficiency Bisoprolol Study II (CIBIS-II): a randomised trial , 1999, The Lancet.

[214]  A. Skene,et al.  Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevation. , 2005, The New England journal of medicine.

[215]  J. Seward,et al.  Mural thrombus in left ventricular aneurysm: incidence, role of angiography, and relation between anticoagulation and embolization. , 1981, Mayo Clinic proceedings.

[216]  K. Huber,et al.  Bivalirudin is superior to heparins alone with bailout GP IIb/IIIa inhibitors in patients with ST-segment elevation myocardial infarction transported emergently for primary percutaneous coronary intervention: a pre-specified analysis from the EUROMAX trial , 2014, European heart journal.

[217]  P. Kirchhof,et al.  2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. , 2016, European heart journal.

[218]  P. Poole‐Wilson,et al.  Effect of long-acting nifedipine on mortality and cardiovascular morbidity in patients with stable angina requiring treatment (ACTION trial): randomised controlled trial , 2004, The Lancet.

[219]  Klaus Rasmussen,et al.  A comparison of coronary angioplasty with fibrinolytic therapy in acute myocardial infarction. , 2003, The New England journal of medicine.

[220]  H. Dargie,et al.  Effect of carvedilol on outcome after myocardial infarction in patients with left-ventricular dysfunction: the CAPRICORN randomised trial , 2001, The Lancet.

[221]  S. Girotra,et al.  Radial versus femoral access for primary percutaneous interventions in ST-segment elevation myocardial infarction patients: a meta-analysis of randomized controlled trials. , 2013, JACC. Cardiovascular interventions.

[222]  C. Lenfant.  Shattuck lecture--clinical research to clinical practice--lost in translation? , 2003, The New England journal of medicine.

[223]  J. López-Sendón,et al.  Electrocardiographic findings in acute right ventricular infarction: sensitivity and specificity of electrocardiographic alterations in right precordial leads V4R, V3R, V1, V2, and V3. , 1985, Journal of the American College of Cardiology.

[224]  G. Schuler,et al.  Intraaortic balloon support for myocardial infarction with cardiogenic shock. , 2012, The New England journal of medicine.

[225]  B. Gersh,et al.  Impact of multivessel disease on reperfusion success and clinical outcomes in patients undergoing primary percutaneous coronary intervention for acute myocardial infarction. , 2007, European heart journal.

[226]  S. Stevens,et al.  for the REACT Trial Investigators. Rescue Angioplasty after Failed Thrombolytic Therapy for Acute Myocardial Infarction , 2005 .

[227]  Nie Fe.  Effect of verapamil on mortality and major events after acute myocardial infarction (the Danish Verapamil Infarction Trial II--DAVIT II) , 1990 .

[228]  S. Mehta,et al.  Nonculprit Vessel Intervention: Let's COMPLETE the Evidence. , 2017, Revista espanola de cardiologia.

[229]  F. Fernández‐Avilés,et al.  Routine invasive strategy within 24 hours of thrombolysis versus ischaemia-guided conservative approach for acute myocardial infarction with ST-segment elevation (GRACIA-1): a randomised controlled trial , 2004, The Lancet.

[230]  J. Emparanza,et al.  Oxygen therapy for acute myocardial infarction. , 2010, The Cochrane database of systematic reviews.

[231]  V. Fuster,et al.  Impact of the Timing of Metoprolol Administration During STEMI on Infarct Size and Ventricular Function. , 2016, Journal of the American College of Cardiology.

[232]  C. Terkelsen,et al.  System delay and mortality among patients with STEMI treated with primary percutaneous coronary intervention. , 2010, JAMA.

[233]  J S Pliskin,et al.  Coronary Artery Bypass Graft Surgery , 2019, Fast Facts for the Cardiac Surgery Nurse.

[234]  T. Investigators,et al.  A comparison of reteplase with alteplase for acute myocardial infarction , 1997 .

[235]  A. Banerjee,et al.  Non-invasive positive pressure ventilation (CPAP or bilevel NPPV) for cardiogenic pulmonary oedema. , 2019, The Cochrane database of systematic reviews.

[236]  Improve-It Investigators.  Ezetimibe added to statin therapy after acute coronary syndromes , 2015 .

[237]  S. Werns.  A systematic review and meta-analysis of intra-aortic balloon pump therapy in ST-elevation myocardial infarction: should we change the guidelines? , 2010 .

[238]  L. Räber,et al.  Effect of biolimus-eluting stents with biodegradable polymer vs bare-metal stents on cardiovascular events among patients with acute myocardial infarction: the COMFORTABLE AMI randomized trial. , 2012, JAMA.

[239]  B. McNally,et al.  Integration of pre-hospital electrocardiograms and ST-elevation myocardial infarction receiving center (SRC) networks: impact on Door-to-Balloon times across 10 independent regions. , 2009, JACC. Cardiovascular interventions.

[240]  Deepak L. Bhatt,et al.  Temporal Trends and Sex Differences in Revascularization and Outcomes of ST-Segment Elevation Myocardial Infarction in Younger Adults in the United States. , 2015, Journal of the American College of Cardiology.

[241]  K. Alexander,et al.  Excess dosing of antiplatelet and antithrombin agents in the treatment of non-ST-segment elevation acute coronary syndromes. , 2005, JAMA.

[242]  S. Z. Abildstrøm,et al.  Women with acute coronary syndrome are less invasively examined and subsequently less treated than men. , 2010, European heart journal.

[243]  B. Pitt,et al.  Eplerenone, a Selective Aldosterone Blocker, in Patients with Left Ventricular Dysfunction after Myocardial Infarction , 2003 .

[244]  E. Topol,et al.  Randomized comparison of rescue angioplasty with conservative management of patients with early failure of thrombolysis for acute anterior myocardial infarction. , 1994, Circulation.

[245]  P. Touboul,et al.  Comparison of primary angioplasty and pre-hospital fibrinolysis in acute myocardial infarction (CAPTIM) trial: a 5-year follow-up. , 2009, European heart journal.

[246]  Therapy Study Investigators.  Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure , 1993, The Lancet.

[247]  C. Held,et al.  All types of atrial fibrillation in the setting of myocardial infarction are associated with impaired outcome , 2016, Heart.

[248]  Tiina Heliö,et al.  Current state of knowledge on aetiology, diagnosis, management, and therapy of myocarditis: a position statement of the European Society of Cardiology Working Group on Myocardial and Pericardial Diseases. , 2013, European heart journal.

[249]  A. Hoes,et al.  2016 European Guidelines on cardiovascular disease prevention in clinical practice. , 2016, Revista espanola de cardiologia.

[250]  Sunil V. Rao,et al.  Radial versus femoral access for coronary angiography and intervention in patients with acute coronary syndromes (RIVAL): a randomised, parallel group, multicentre trial , 2011, The Lancet.

[251]  R. Califf,et al.  Ezetimibe Added to Statin Therapy after Acute Coronary Syndromes. , 2015, The New England journal of medicine.

[252]  P. Touboul,et al.  Primary angioplasty versus prehospital fibrinolysis in acute myocardial infarction: a randomised study , 2002, The Lancet.

[253]  Thomas R Fanshawe,et al.  Combined pharmacotherapy and behavioural interventions for smoking cessation. , 2016, The Cochrane database of systematic reviews.

[254]  C. Lau,et al.  Transient atrial fibrillation complicating acute inferior myocardial infarction: implications for future risk of ischemic stroke. , 2007, Chest.

[255]  O. Simonetti,et al.  The use of contrast-enhanced magnetic resonance imaging to identify reversible myocardial dysfunction. , 2000, The New England journal of medicine.

[256]  E. Keeley,et al.  Left Ventricular Mural Thrombus after Acute Myocardial Infarction , 1996, Clinical cardiology.

[257]  E. Vicaut,et al.  Efficacy and safety of enoxaparin versus unfractionated heparin during percutaneous coronary intervention: systematic review and meta-analysis , 2012, BMJ : British Medical Journal.

[258]  P. Best,et al.  Acute myocardial infarction due to left circumflex artery occlusion and significance of ST-segment elevation. , 2010, The American journal of cardiology.

[259]  G. Lip,et al.  Expert position paper on the use of proton pump inhibitors in patients with cardiovascular disease and antithrombotic therapy. , 2013, European heart journal.

[260]  Lluís Mont,et al.  2013 ESC Guidelines on cardiac pacing and cardiac resynchronization therapy: the Task Force on cardiac pacing and resynchronization therapy of the European Society of Cardiology (ESC). Developed in collaboration with the European Heart Rhythm Association (EHRA). , 2013, European heart journal.

[261]  P. Armstrong,et al.  Diagnosing acute myocardial infarction in patients with left bundle branch block. , 2011, The American journal of cardiology.

[262]  A. Neskovic,et al.  Detection of significant residual stenosis of the infarct‐related artery after thrombolysis by high‐dose dipyridamole echocardiography test: Is it detected often enough? , 1997, Clinical cardiology.

[263]  A. Hall,et al.  Trends in hospital treatments, including revascularisation, following acute myocardial infarction, 2003–2010: a multilevel and relative survival analysis for the National Institute for Cardiovascular Outcomes Research (NICOR) , 2013, Heart.

[264]  H. White,et al.  Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock. , 1999, The New England journal of medicine.

[265]  B. Psaty,et al.  Nifedipine. Dose-related increase in mortality in patients with coronary heart disease. , 1995, Circulation.

[266]  J. McLean.  Emergency Department Bypass for ST-Segment-Elevation Myocardial Infarction Patients Identified with a Prehospital Electrocardiogram: A Report From the American Heart Association Mission: Lifeline Program , 2013 .

[267]  Pierre Coste,et al.  Should patients with acute coronary disease be stratified for management according to their risk? Derivation, external validation and outcomes using the updated GRACE risk score , 2014, BMJ Open.

[268]  David Brieger,et al.  Acute coronary syndromes without chest pain, an underdiagnosed and undertreated high-risk group: insights from the Global Registry of Acute Coronary Events. , 2004, Chest.

[269]  J. D. de Lemos,et al.  Evolving considerations in the management of patients with left bundle branch block and suspected myocardial infarction. , 2012, Journal of the American College of Cardiology.

[270]  O. Faergeman,et al.  Comparison of atorvastatin 80 mg/day versus simvastatin 20 to 40 mg/day on frequency of cardiovascular events late (five years) after acute myocardial infarction (from the Incremental Decrease in End Points through Aggressive Lipid Lowering [IDEAL] trial). , 2010, The American journal of cardiology.

[271]  Michael F. Oliver,et al.  Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes. The MIRACL study. , 2001, Indian heart journal.

[272]  J. Madias.  The nonspecificity of ST-segment elevation > or =5.0 mm in V1-V3 in the diagnosis of acute myocardial infarction in the presence of ventricular paced rhythm. , 2004, Journal of electrocardiology.

[273]  J. Hartikainen,et al.  Reperfusion therapy for ST elevation acute myocardial infarction in Europe: description of the current situation in 30 countries , 2009, European heart journal.

[274]  J. Critchley,et al.  Mortality risk reduction associated with smoking cessation in patients with coronary heart disease: a systematic review. , 2003, JAMA.

[275]  L. Azzalini,et al.  Feasibility and Safety of an Early Discharge Strategy after Low-Risk Acute Myocardial Infarction Treated with Primary Percutaneous Coronary Intervention: The EDAMI Pilot Trial , 2015, Cardiology.

[276]  Paul Burton,et al.  Rivaroxaban in patients with a recent acute coronary syndrome. , 2012, The New England journal of medicine.

[277]  A. Castro‐Beiras,et al.  Safety and feasibility of returning patients early to their originating centers after transfer for primary percutaneous coronary intervention. , 2009, Revista espanola de cardiologia.

[278]  A. Hoes,et al.  2016 ESC/EAS Guidelines for the Management of Dyslipidaemias: The Task Force for the Management of Dyslipidaemias of the European Society of Cardiology (ESC) and European Atherosclerosis Society (EAS) Developed with the special contribution of the European Assocciation for Cardiovascular Prevention , 2016, Atherosclerosis.

[279]  K. Thygesen,et al.  How to set up an effective national primary angioplasty network: lessons learned from five European countries. , 2009, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[280]  G. Montalescot,et al.  Prehospital ticagrelor in ST-segment elevation myocardial infarction. , 2014, The New England journal of medicine.

[281]  V. Fuster,et al.  Neutrophil stunning by metoprolol reduces infarct size , 2017, Nature Communications.

[282]  D J Torgerson,et al.  Pragmatic trials: lab meets bedside , 2019, The British journal of dermatology.

[283]  C. Granger,et al.  Association of Rapid Care Process Implementation on Reperfusion Times Across Multiple ST-Segment–Elevation Myocardial Infarction Networks , 2017, Circulation. Cardiovascular interventions.

[284]  C. Di Mario,et al.  Reperfusion therapy for ST elevation acute myocardial infarction 2010/2011: current status in 37 ESC countries. , 2014, European heart journal.

[285]  W. Wojakowski,et al.  Effects of preoperative aspirin in coronary artery bypass grafting: a double-blind, placebo-controlled, randomized trial. , 2012, The Journal of thoracic and cardiovascular surgery.

[286]  P. Armstrong,et al.  Incidence and predictors of bleeding events after fibrinolytic therapy with fibrin-specific agents: a comparison of TNK-tPA and rt-PA. , 2001, European heart journal.

[287]  B. Gersh,et al.  Bivalirudin during primary PCI in acute myocardial infarction. , 2008, The New England journal of medicine.

[288]  Jeroen J. Bax,et al.  Early Reperfusion Therapy Affects Inducibility, Cycle Length, and Occurrence of Ventricular Tachycardia Late After Myocardial Infarction , 2011, Circulation. Arrhythmia and electrophysiology.

[289]  H. Heidbuchel,et al.  Enoxaparin as Adjunctive Antithrombin Therapy for ST-Elevation Myocardial Infarction: Results of the ENTIRE-Thrombolysis in Myocardial Infarction (TIMI) 23 Trial , 2002, Circulation.

[290]  B. Pathik,et al.  Troponin-positive chest pain with unobstructed coronary arteries: incremental diagnostic value of cardiovascular magnetic resonance imaging. , 2016, European heart journal cardiovascular Imaging.

[291]  T. Fukui,et al.  Differential Time Trends of Outcomes and Costs of Care for Acute Myocardial Infarction Hospitalizations by ST Elevation and Type of Intervention in the United States, 2001–2011 , 2015, Journal of the American Heart Association.

[292]  S. Ball,et al.  ACE inhibition, atherosclerosis and myocardial infarction--the AIRE Study in practice. Acute Infarction Ramipril Efficacy Study. , 1994, European heart journal.

[293]  Edwin Wu,et al.  Prevalence of regional myocardial thinning and relationship with myocardial scarring in patients with coronary artery disease. , 2013, JAMA.

[294]  Ian Graham,et al.  ESC/EAS Guidelines for the management of dyslipidaemias: the Task Force for the management of dyslipidaemias of the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS). , 2011, Atherosclerosis.

[295]  E. Antman,et al.  Enoxaparin vs. unfractionated heparin with fibrinolysis for ST-elevation myocardial infarction in elderly and younger patients: results from ExTRACT-TIMI 25. , 2007, European heart journal.

[296]  S. Yusuf,et al.  Dose comparisons of clopidogrel and aspirin in acute coronary syndromes. , 2010, The New England journal of medicine.

[297]  P. Stella,et al.  Effect of early, pre-hospital initiation of high bolus dose tirofiban in patients with ST-segment elevation myocardial infarction on short- and long-term clinical outcome. , 2010, Journal of the American College of Cardiology.

[298]  R. Collins,et al.  Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170 000 participants in 26 randomised trials , 2010, The Lancet.

[299]  J. Nicholl,et al.  Noninvasive ventilation in acute cardiogenic pulmonary edema. , 2008, The New England journal of medicine.

[300]  B. Pitt,et al.  The effect of spironolactone on morbidity and mortality in patients with severe heart failure. Randomized Aldactone Evaluation Study Investigators. , 1999, The New England journal of medicine.

[301]  A. Kastrati,et al.  Bivalirudin versus unfractionated heparin during percutaneous coronary intervention. , 2008, The New England journal of medicine.

[302]  M. Scheinman,et al.  Polymorphous Ventricular Tachycardia Associated With Acute Myocardial Infarction , 1991, Circulation.

[303]  J. Tijssen,et al.  Right ventricular dysfunction is an independent predictor for mortality in ST‐elevation myocardial infarction patients presenting with cardiogenic shock on admission , 2010, European journal of heart failure.

[304]  K. Coyne,et al.  Randomized Comparison of Enoxaparin, a Low-Molecular-Weight Heparin, With Unfractionated Heparin Adjunctive to Recombinant Tissue Plasminogen Activator Thrombolysis and Aspirin: Second Trial of Heparin and Aspirin Reperfusion Therapy (HART II) , 2001, Circulation.

[305]  M. Dzingina,et al.  Hyperglycaemia in acute coronary syndromes: summary of NICE guidance , 2011, BMJ : British Medical Journal.

[306]  Felix Zijlstra,et al.  Prognostic Assessment of Patients With Acute Myocardial Infarction Treated With Primary Angioplasty: Implications for Early Discharge , 2004, Circulation.

[307]  C. Granger,et al.  Emergency Department Bypass for ST-Segment–Elevation Myocardial Infarction Patients Identified With a Prehospital Electrocardiogram: A Report From the American Heart Association Mission Lifeline Program , 2013, Circulation.

[308]  M. Ashburn,et al.  Cardiac Effects of Opioid Therapy. , 2015, Pain medicine.

[309]  D. Chamberlain,et al.  Thrombolysis during resuscitation for out-of-hospital cardiac arrest. , 2008, The New England journal of medicine.

[310]  J. Kastrup,et al.  Short- and long-term cause of death in patients treated with primary PCI for STEMI. , 2014, Journal of the American College of Cardiology.

[311]  G. Lip,et al.  Prevention of Bleeding in Patients with Atrial Fibrillation Undergoing PCI. , 2016, The New England journal of medicine.

[312]  A. Camm,et al.  Cardiac arrhythmias in acute coronary syndromes: position paper from the joint EHRA, ACCA, and EAPCI task force. , 2015, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[313]  J. Nielsen,et al.  ESC Guidelines on cardiac pacing and cardiac resynchronization therapy , 2014 .

[314]  M. Dalby,et al.  Transfer for Primary Angioplasty Versus Immediate Thrombolysis in Acute Myocardial Infarction: A Meta-Analysis , 2003, Circulation.

[315]  B. Pitt,et al.  The Effect of Spironolactone on Morbidity and Mortality in Patients with Severe Heart Failure , 2000 .

[316]  Sunil V. Rao,et al.  Radial versus femoral access in patients with acute coronary syndromes undergoing invasive management: a randomised multicentre trial , 2015, The Lancet.

[317]  J. Zamorano,et al.  The use of echocardiography in acute cardiovascular care: Recommendations of the European Association of Cardiovascular Imaging and the Acute Cardiovascular Care Association. , 2014, European heart journal. Acute cardiovascular care.

[318]  C. Naugler,et al.  Fasting time and lipid levels in a community-based population: a cross-sectional study. , 2012, Archives of internal medicine.

[319]  S. Windecker,et al.  Invasive coronary treatment strategies for out-of-hospital cardiac arrest: a consensus statement from the European association for percutaneous cardiovascular interventions (EAPCI)/stent for life (SFL) groups. , 2014, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[320]  Salim Yusuf,et al.  The role of fondaparinux as an adjunct to thrombolytic therapy in acute myocardial infarction: a subgroup analysis of the OASIS-6 trial. , 2008, European heart journal.

[321]  Fredrik Folke,et al.  Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillation. , 2010, Archives of internal medicine.

[322]  D. Atar,et al.  ESC Guidelines for the Management of Acute Myocardial Infarction in Patients Presenting With ST-Segment Elevation , 2013 .

[323]  G. Lamas,et al.  Lack of benefit from percutaneous intervention of persistently occluded infarct arteries after the acute phase of myocardial infarction is time independent: insights from Occluded Artery Trial. , 2008, European heart journal.

[324]  C. Henrikson,et al.  Chest Pain Relief by Nitroglycerin Does Not Predict Active Coronary Artery Disease , 2003, Annals of Internal Medicine.

[325]  C. Terkelsen,et al.  Urban and rural implementation of pre-hospital diagnosis and direct referral for primary percutaneous coronary intervention in patients with acute ST-elevation myocardial infarction. , 2011, European heart journal.

[326]  G. Thanassoulis,et al.  Fractional Flow Reserve–Guided Multivessel Angioplasty in Myocardial Infarction. , 2017, The New England journal of medicine.

[327]  Deepak L. Bhatt,et al.  Effect of cangrelor on periprocedural outcomes in percutaneous coronary interventions: a pooled analysis of patient-level data , 2013, The Lancet.

[328]  S. Yusuf,et al.  Association of Diet, Exercise, and Smoking Modification With Risk of Early Cardiovascular Events After Acute Coronary Syndromes , 2010, Circulation.

[329]  E. J. Brown,et al.  Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. , 1992, The New England journal of medicine.

[330]  J. Ferrières,et al.  Association of changes in clinical characteristics and management with improvement in survival among patients with ST-elevation myocardial infarction. , 2012, JAMA.

[331]  Marc P. Bonaca,et al.  Long-term use of ticagrelor in patients with prior myocardial infarction. , 2015, The New England journal of medicine.

[332]  E. Vicaut,et al.  Early Aldosterone Blockade in Acute Myocardial Infarction: The ALBATROSS Randomized Clinical Trial. , 2016, Journal of the American College of Cardiology.

[333]  Raymond C. Schneider,et al.  ISIS-4: A randomised factorial trial assessing early oral captopril, oral mononitrate, and intravenous magnesium sulphate in 58 050 patients with suspected acute myocardial infarction , 1995, The Lancet.

[334]  M. Flather,et al.  Early eplerenone treatment in patients with acute ST-elevation myocardial infarction without heart failure: the Randomized Double-Blind Reminder Study. , 2014, European heart journal.

[335]  T. Kellerth,et al.  Left bundle branch block and suspected myocardial infarction: does chronicity of the branch block matter? , 2013, European heart journal. Acute cardiovascular care.

[336]  David P Miller,et al.  Hospital Delays in Reperfusion for ST-Elevation Myocardial Infarction: Implications When Selecting a Reperfusion Strategy , 2006, Circulation.

[337]  C. Granger,et al.  Primary percutaneous coronary intervention compared with fibrinolysis for myocardial infarction in diabetes mellitus: results from the Primary Coronary Angioplasty vs Thrombolysis-2 trial. , 2007, Archives of internal medicine.

[338]  E. Boersma,et al.  Does time matter? A pooled analysis of randomized clinical trials comparing primary percutaneous coronary intervention and in-hospital fibrinolysis in acute myocardial infarction patients. , 2006, European heart journal.

[339]  C. Berry,et al.  Randomized trial of preventive angioplasty in myocardial infarction. , 2013, The New England journal of medicine.

[340]  Marcelo Park,et al.  Randomized, prospective trial of oxygen, continuous positive airway pressure, and bilevel positive airway pressure by face mask in acute cardiogenic pulmonary edema* , 2004, Critical care medicine.

[341]  Holger Thiele,et al.  Comprehensive prognosis assessment by CMR imaging after ST-segment elevation myocardial infarction. , 2014, Journal of the American College of Cardiology.

[342]  Vic Hasselblad,et al.  Impact of the pulmonary artery catheter in critically ill patients: meta-analysis of randomized clinical trials. , 2005, JAMA.

[343]  P. Kirchhof,et al.  2016 ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. , 2016, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[344]  G. Wells,et al.  Combined angioplasty and pharmacological intervention versus thrombolysis alone in acute myocardial infarction (CAPITAL AMI study). , 2005, Journal of the American College of Cardiology.

[345]  O. Hlinomaz,et al.  Primary angioplasty in acute myocardial infarction with right bundle branch block: should new onset right bundle branch block be added to future guidelines as an indication for reperfusion therapy? , 2011, European heart journal.

[346]  K. Jolly,et al.  Home based versus centre based cardiac rehabilitation: Cochrane systematic review and meta-analysis , 2010, BMJ : British Medical Journal.

[347]  D. McManus,et al.  Recent trends in the incidence, treatment, and outcomes of patients with STEMI and NSTEMI. , 2011, The American journal of medicine.

[348]  K. Kern,et al.  Emergent percutaneous coronary intervention for resuscitated victims of out‐of‐hospital cardiac arrest , 2009, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[349]  J. Smith,et al.  Effect of upstream clopidogrel treatment in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. , 2011, European heart journal.

[350]  F. Van de Werf,et al.  Evolving therapies for myocardial ischemia/reperfusion injury. , 2015, Journal of the American College of Cardiology.

[351]  Stephane Heritier,et al.  Intensive versus conventional glucose control in critically ill patients. , 2009, The New England journal of medicine.

[352]  S. Yusuf,et al.  Concomitant Use of Antiplatelet Therapy with Dabigatran or Warfarin in the Randomized Evaluation of Long-Term Anticoagulation Therapy (RE-LY) Trial , 2013, Circulation.

[353]  F. Van de Werf,et al.  Effect of tilarginine acetate in patients with acute myocardial infarction and cardiogenic shock: the TRIUMPH randomized controlled trial. , 2007, JAMA.

[354]  Z. Siudak,et al.  Impact of multivessel coronary artery disease and noninfarct-related artery revascularization on outcome of patients with ST-elevation myocardial infarction transferred for primary percutaneous coronary intervention (from the EUROTRANSFER Registry). , 2010, The American journal of cardiology.

[355]  Robert A. Berg,et al.  International Consensus on Cardiopulmonary Resuscitation and mergency Cardiovascular Care Science with Treatment ecommendations , 2015 .

[356]  W. Toff,et al.  Fitness to fly for passengers with cardiovascular disease. , 2010, Heart.

[357]  A Gray,et al.  Blood glucose self-monitoring in type 2 diabetes: a randomised controlled trial. , 2009, Health technology assessment.

[358]  R. Erbel,et al.  Prospective, randomised trial of the time dependent antiplatelet effects of 500 mg and 250 mg acetylsalicylic acid i. v. and 300 mg p. o. in ACS (ACUTE) , 2017, Thrombosis and Haemostasis.

[359]  R. Taylor,et al.  Cardiac rehabilitation for people with heart disease: an overview of Cochrane systematic reviews. , 2014, International journal of cardiology.

[360]  G. Maurer,et al.  Implementation of Guidelines Improves the Standard of Care: The Viennese Registry on Reperfusion Strategies in ST-Elevation Myocardial Infarction (Vienna STEMI Registry) , 2006, Circulation.

[361]  David Vancraeynest,et al.  Prognostic value of myocardial viability by delayed-enhanced magnetic resonance in patients with coronary artery disease and low ejection fraction: impact of revascularization therapy. , 2012, Journal of the American College of Cardiology.

[362]  R. Collins,et al.  Addition of clopidogrel to aspirin in 45 852 patients with acute myocardial infarction: randomised placebo-controlled trial , 2005, The Lancet.

[363]  N. Parakh.  Intraaortic balloon support for myocardial infarction with cardiogenic shock , 2012 .

[364]  Mao Chen,et al.  Meta-Analysis of Relation Between Oral β-Blocker Therapy and Outcomes in Patients With Acute Myocardial Infarction Who Underwent Percutaneous Coronary Intervention. , 2015, The American journal of cardiology.

[365]  Biao Xu,et al.  Safety and efficacy of anti-PCSK9 antibodies: a meta-analysis of 25 randomized, controlled trials , 2015, BMC Medicine.

[366]  L. Morrison,et al.  Mortality and prehospital thrombolysis for acute myocardial infarction: A meta-analysis. , 2000, JAMA.

[367]  J. Trickett,et al.  A citywide protocol for primary PCI in ST-segment elevation myocardial infarction. , 2008, The New England journal of medicine.

[368]  D. Atar,et al.  ESC working group position paper on myocardial infarction with non-obstructive coronary arteries. , 2016, European heart journal.

[369]  R. Dreyer,et al.  Return to Work After Acute Myocardial Infarction: Comparison Between Young Women and Men , 2016, Circulation. Cardiovascular quality and outcomes.

[370]  L. Jordaens,et al.  Conversion of atrial fibrillation to sinus rhythm and rate control by digoxin in comparison to placebo. , 1997, European heart journal.

[371]  S. Solomon,et al.  Relation of mortality to failure to prescribe beta blockers acutely in patients with sustained ventricular tachycardia and ventricular fibrillation following acute myocardial infarction (from the VALsartan In Acute myocardial iNfarcTion trial [VALIANT] Registry). , 2008, The American journal of cardiology.

[372]  Effect of carvedilol on survival in severe chronic heart failure. , 2001 .

[373]  K. Kern,et al.  Therapeutic Hypothermia and Stent Thrombosis: A Nationwide Analysis. , 2016, JACC. Cardiovascular interventions.

[374]  M. Velázquez,et al.  Post-resuscitation electrocardiograms, acute coronary findings and in-hospital prognosis of survivors of out-of-hospital cardiac arrest. , 2014, Resuscitation.

[375]  J. Kautzner,et al.  Catheter ablation of arrhythmic storm triggered by monomorphic ectopic beats in patients with coronary artery disease , 2009, Journal of Interventional Cardiac Electrophysiology.

[376]  L. Shaw,et al.  Myocardial viability testing and impact of revascularization on prognosis in patients with coronary artery disease and left ventricular dysfunction: a meta-analysis. , 2002, Journal of the American College of Cardiology.

[377]  M. Bourassa,et al.  Native coronary disease progression exceeds failed revascularization as cause of angina after five years in the Bypass Angioplasty Revascularization Investigation (BARI). , 2004, Journal of the American College of Cardiology.

[378]  J. Fajadet,et al.  "Stent 4 Life" targeting PCI at all who will benefit the most. A joint project between EAPCI, Euro-PCR, EUCOMED and the ESC Working Group on Acute Cardiac Care. , 2009, EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology.

[379]  D. Wald,et al.  Adherence to drugs that prevent cardiovascular disease: meta-analysis on 376,162 patients. , 2012, The American journal of medicine.

[380]  G S Wagner,et al.  Electrocardiographic diagnosis of evolving acute myocardial infarction in the presence of left bundle-branch block. GUSTO-1 (Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries) Investigators. , 1996, The New England journal of medicine.

[381]  A. Hofman,et al.  Incidence of recognized and unrecognized myocardial infarction in men and women aged 55 and older: the Rotterdam Study. , 2006, European heart journal.

[382]  K. Nademanee,et al.  Treating electrical storm : sympathetic blockade versus advanced cardiac life support-guided therapy. , 2000, Circulation.

[383]  Fiona Lough MPhil Mcsp.  Exercise-based Cardiac Rehabilitation , 1997 .

[384]  T. Harr,et al.  Clinical outcomes of primary stenting versus balloon angioplasty in patients with myocardial infarction: a meta-analysis of randomized controlled trials. , 2004, The American journal of medicine.

[385]  L. Wallentin,et al.  Pre-hospital thrombolysis delivered by paramedics is associated with reduced time delay and mortality in ambulance-transported real-life patients with ST-elevation myocardial infarction. , 2006, European heart journal.

[386]  J. McMurray,et al.  Multidisciplinary strategies for the management of heart failure patients at high risk for admission: a systematic review of randomized trials. , 2004, Journal of the American College of Cardiology.

[387]  S. Bangalore.  Drug-Eluting or Bare-Metal Stents for Coronary Artery Disease , 2016, The New England journal of medicine.

[388]  C. Thomson,et al.  Hospital- and clinic-based smoking cessation interventions for smokers with cardiovascular disease. , 2003, Progress in cardiovascular diseases.

[389]  V. Fuster,et al.  Early Intravenous Beta-Blockers in Patients With ST-Segment Elevation Myocardial Infarction Before Primary Percutaneous Coronary Intervention. , 2016, Journal of the American College of Cardiology.

[390]  V. Fuster,et al.  A polypill strategy to improve adherence: results from the FOCUS project. , 2014, Journal of the American College of Cardiology.

[391]  K. Dickstein,et al.  Safety and health status following early discharge in patients with acute myocardial infarction treated with primary PCI: a randomized trial , 2015, European journal of preventive cardiology.

[392]  S. Sonnad,et al.  Using EMS Dispatch to Trigger STEMI Alerts Decreases Door-to-Balloon Times , 2015, The western journal of emergency medicine.

[393]  P. Touboul,et al.  Impact of Time to Treatment on Mortality After Prehospital Fibrinolysis or Primary Angioplasty: Data From the CAPTIM Randomized Clinical Trial , 2003, Circulation.

[394]  K. Alexander,et al.  Clinical outcomes with β-blockers for myocardial infarction: a meta-analysis of randomized trials. , 2014, The American journal of medicine.

[395]  F. Van de Werf,et al.  Dabigatran vs. placebo in patients with acute coronary syndromes on dual antiplatelet therapy: a randomized, double-blind, phase II trial. , 2011, European heart journal.

[396]  A. van Rossum,et al.  Long-term follow-up of the viability guided angioplasty after acute myocardial infarction (VIAMI) trial. , 2012, International journal of cardiology.

[397]  R. Charnigo,et al.  Digoxin and short term mortality after acute STEMI: Results from the MAGIC trial. , 2016, International journal of cardiology.

[398]  P. Croisille,et al.  Comparison of Immediate With Delayed Stenting Using the Minimalist Immediate Mechanical Intervention Approach in Acute ST-Segment–Elevation Myocardial Infarction: The MIMI Study , 2016, Circulation. Cardiovascular interventions.

[399]  H. Krumholz,et al.  Development of Systems of Care for ST-Elevation Myocardial Infarction Patients: Gaps, Barriers, and Implications , 2007, Circulation.

[400]  Michael Holzer,et al.  Mild therapeutic hypothermia to improve the neurologic outcome after cardiac arrest , 2002 .

[401]  G. Stone,et al.  Bivalirudin versus heparin with or without glycoprotein IIb/IIIa inhibitors in patients with STEMI undergoing primary PCI: An updated meta-analysis of 10,350 patients from five randomized clinical trials , 2016, European heart journal. Acute cardiovascular care.

[402]  T. Ivert,et al.  Coronary artery bypass grafting-related bleeding complications in patients treated with ticagrelor or clopidogrel: a nationwide study , 2015, European heart journal.

[403]  A. Kaltoft,et al.  Clinical impact of thrombectomy in acute ST-elevation myocardial infarction: an individual patient-data pooled analysis of 11 trials. , 2009, European heart journal.

[404]  N. Dudley.  Thrombolytic therapy in the elderly. , 1991, Postgraduate medical journal.

[405]  J. Tijssen,et al.  A systematic review and meta-analysis of intra-aortic balloon pump therapy in ST-elevation myocardial infarction: should we change the guidelines? , 2008, European heart journal.

[406]  I. Xanthopoulou,et al.  Morphine Is Associated With a Delayed Activity of Oral Antiplatelet Agents in Patients With ST-Elevation Acute Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention , 2014, Circulation. Cardiovascular interventions.

[407]  L. Newby,et al.  Frequency and consequences of recording an electrocardiogram >10 minutes after arrival in an emergency room in non-ST-segment elevation acute coronary syndromes (from the CRUSADE Initiative). , 2006, The American journal of cardiology.

[408]  G. Stone,et al.  Clinical outcomes with drug-eluting and bare-metal stents in patients with ST-segment elevation myocardial infarction: evidence from a comprehensive network meta-analysis. , 2013, Journal of the American College of Cardiology.

[409]  J. Cohn,et al.  The effect of carvedilol on morbidity and mortality in patients with chronic heart failure. U.S. Carvedilol Heart Failure Study Group. , 1996, The New England journal of medicine.

[410]  Douglas L Packer,et al.  Amiodarone or an implantable cardioverter-defibrillator for congestive heart failure. , 2005, The New England journal of medicine.

[411]  Harlan M Krumholz,et al.  Association of door-to-balloon time and mortality in patients admitted to hospital with ST elevation myocardial infarction: national cohort study , 2009, BMJ : British Medical Journal.

[412]  C. Terkelsen,et al.  System delay and timing of intervention in acute myocardial infarction (from the Danish Acute Myocardial Infarction-2 [DANAMI-2] trial). , 2011, The American journal of cardiology.

[413]  G. Boysen,et al.  European Guidelines on Cardiovascular Disease Prevention , 2009, International journal of stroke : official journal of the International Stroke Society.

[414]  J R Hughes,et al.  Antidepressants for smoking cessation. , 2007, The Cochrane database of systematic reviews.

[415]  R. de Caterina,et al.  Pre-hospital reperfusion therapy: a strategy to improve therapeutic outcome in patients with ST-elevation myocardial infarction. , 2005, European heart journal.

[416]  Kenneth W Lin,et al.  Nicotine receptor partial agonists for smoking cessation. , 2011, American family physician.

[417]  Malte Kelm,et al.  Effects of Proprotein Convertase Subtilisin/Kexin Type 9 Antibodies in Adults With Hypercholesterolemia: A Systematic Review and Meta-analysis. , 2015, Annals of internal medicine.

[418]  G. Stone,et al.  Safety and cost-effectiveness of early discharge after primary angioplasty in low risk patients with acute myocardial infarction. PAMI-II Investigators. Primary Angioplasty in Myocardial Infarction. , 1998, Journal of the American College of Cardiology.

[419]  Cheuk-Kwan Sun,et al.  Early extracorporeal membrane oxygenator-assisted primary percutaneous coronary intervention improved 30-day clinical outcomes in patients with ST-segment elevation myocardial infarction complicated with profound cardiogenic shock , 2010, Critical care medicine.

[420]  P. Rautava,et al.  Gender and in-hospital mortality of ST-segment elevation myocardial infarction (from a multihospital nationwide registry study of 31,689 patients). , 2015, The American journal of cardiology.

[421]  R. de Caterina,et al.  Antiplatelet agents for the treatment and prevention of atherothrombosis. , 2011, European heart journal.

[422]  M. Marszałł,et al.  Morphine delays and attenuates ticagrelor exposure and action in patients with myocardial infarction: the randomized, double-blind, placebo-controlled IMPRESSION trial , 2015, European heart journal.

[423]  K. Anstrom,et al.  Ultrafiltration in decompensated heart failure with cardiorenal syndrome. , 2012, The New England journal of medicine.

[424]  J. Boura,et al.  Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction : a quantitative review of 23 randomised trials , 2022 .

[425]  Y. Cha,et al.  Long-Term Outcomes in Survivors of Early Ventricular Arrhythmias After Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction Treated With Percutaneous Coronary Intervention. , 2016, The American journal of cardiology.

[426]  Mike Fisher,et al.  Unfractionated heparin versus bivalirudin in primary percutaneous coronary intervention (HEAT-PPCI): an open-label, single centre, randomised controlled trial , 2014, The Lancet.

[427]  Marlene R. Miller,et al.  The evidence regarding the drugs used for ventricular rate control. , 2000, The Journal of family practice.

[428]  D. Chew,et al.  The impact of increased age on outcome from a strategy of early invasive management and revascularisation in patients with acute coronary syndromes: retrospective analysis study from the ACACIA registry , 2012, BMJ Open.

[429]  J. Gore,et al.  Thirty-Year Trends (1975 to 2005) in the Magnitude of, Management of, and Hospital Death Rates Associated With Cardiogenic Shock in Patients With Acute Myocardial Infarction: A Population-Based Perspective , 2009, Circulation.

[430]  J. Ferrières,et al.  Comparison of Thrombolysis Followed by Broad Use of Percutaneous Coronary Intervention With Primary Percutaneous Coronary Intervention for , 2022 .

[431]  R. Welsh,et al.  Treatment choices in elderly patients with ST: elevation myocardial infarction—insights from the Vital Heart Response registry , 2015, Open Heart.

[432]  J. Zamorano,et al.  Emergency echocardiography: the European Association of Cardiovascular Imaging recommendations. , 2013, European Heart Journal-Cardiovascular Imaging.

[433]  P. Weale,et al.  Quantifying the Area at Risk in Reperfused ST-Segment–Elevation Myocardial Infarction Patients Using Hybrid Cardiac Positron Emission Tomography–Magnetic Resonance Imaging , 2016, Circulation. Cardiovascular imaging.

[434]  J. Piccini,et al.  Prognostic significance of postprocedural sustained ventricular tachycardia or fibrillation in patients undergoing primary percutaneous coronary intervention (from the HORIZONS-AMI Trial). , 2012, The American journal of cardiology.

[435]  L. Newby,et al.  Characterization and outcomes of women and men with non-ST-segment elevation myocardial infarction and nonobstructive coronary artery disease: results from the Can Rapid Risk Stratification of Unstable Angina Patients Suppress Adverse Outcomes with Early Implementation of the ACC/AHA Guidelines (CRU , 2009, American heart journal.

[436]  R. Collins,et al.  Early intravenous then oral metoprolol in 45 852 patients with acute myocardial infarction: randomised placebo-controlled trial , 2005, The Lancet.

[437]  Sunil V. Rao,et al.  Randomized trial of primary PCI with or without routine manual thrombectomy. , 2015, The New England journal of medicine.

[438]  J. Loscalzo,et al.  Lipid levels after acute coronary syndromes. , 2008, Journal of the American College of Cardiology.

[439]  Christopher P Cannon,et al.  Intensive versus moderate lipid lowering with statins after acute coronary syndromes. , 2004, The New England journal of medicine.

[440]  G. Angelini,et al.  Myocardial Infarction With Nonobstructed Coronary Arteries: Impact of CMR Early After Presentation. , 2017, JACC. Cardiovascular imaging.

[441]  Johan Herlitz,et al.  Indications for fibrinolytic therapy in suspected acute myocardial infarction : collaborative overview of early mortality and major morbidity results from all randomised trials of more than 1000 patients , 1994 .

[442]  H. Bøtker,et al.  Targeting reperfusion injury in patients with ST-segment elevation myocardial infarction: trials and tribulations , 2016, European heart journal.

[443]  J. Ravkilde,et al.  Acute coronary angiography in patients resuscitated from out-of-hospital cardiac arrest--a systematic review and meta-analysis. , 2012, Resuscitation.

[444]  P. Janský,et al.  Pre-hospital treatment of STEMI patients. A scientific statement of the Working Group Acute Cardiac Care of the European Society of Cardiology , 2011, Acute cardiac care.

[445]  A. Parkhomenko,et al.  Recommendations for the structure, organization, and operation of intensive cardiac care units. , 2005, European heart journal.

[446]  A. Kastrati,et al.  Bleeding after percutaneous coronary intervention with Bivalirudin or unfractionated Heparin and one-year mortality. , 2010, The American journal of cardiology.

[447]  R. Califf,et al.  Patients with prolonged ischemic chest pain and presumed-new left bundle branch block have heterogeneous outcomes depending on the presence of ST-segment changes. , 2005, Journal of the American College of Cardiology.

[448]  M. Flather,et al.  Immediate angioplasty versus standard therapy with rescue angioplasty after thrombolysis in the Combined Abciximab REteplase Stent Study in Acute Myocardial Infarction (CARESS-in-AMI): an open, prospective, randomised, multicentre trial , 2008, The Lancet.

[449]  L. Shaw,et al.  Early dipyridamole (99m)Tc-sestamibi single photon emission computed tomographic imaging 2 to 4 days after acute myocardial infarction predicts in-hospital and postdischarge cardiac events: comparison with submaximal exercise imaging. , 1999, Circulation.

[450]  R. Costa,et al.  Thrombus aspiration in ST-segment elevation myocardial infarction. , 2015, Minerva cardioangiologica.

[451]  L. Rallidis,et al.  The fundamental importance of smoking cessation in those with premature ST-segment elevation acute myocardial infarction , 2016, Current opinion in cardiology.

[452]  J. Shalhoub,et al.  Trends in Mortality From Ischemic Heart Disease and Cerebrovascular Disease in Europe: 1980 to 2009 , 2016, Circulation.

[453]  P. Ponikowski,et al.  [2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure]. , 2016, Kardiologia polska.

[454]  R. Califf,et al.  Antiarrhythmic drug therapy for sustained ventricular arrhythmias complicating acute myocardial infarction* , 2009, Critical care medicine.

[455]  D. DeMets,et al.  Effect of Carvedilol on the Morbidity of Patients With Severe Chronic Heart Failure: Results of the Carvedilol Prospective Randomized Cumulative Survival (COPERNICUS) Study , 2002, Circulation.

[456]  J. Tamayo-Sarver,et al.  Effect of Prehospital Cardiac Catheterization Lab Activation on Door-to-Balloon Time, Mortality, and False-Positive Activation , 2014, Prehospital emergency care : official journal of the National Association of EMS Physicians and the National Association of State EMS Directors.

[457]  Fach,et al.  Effect of metoprolol CR/XL in chronic heart failure: Metoprolol CR/XL Randomised Intervention Trial in-Congestive Heart Failure (MERIT-HF) , 1999, The Lancet.

[458]  G. Vetrovec,et al.  Left circumflex occlusion in acute myocardial infarction (from the National Cardiovascular Data Registry). , 2011, American Journal of Cardiology.

[459]  X. Jouven,et al.  Atrial Fibrillation and Death After Myocardial Infarction: A Community Study , 2011, Circulation.

[460]  P. Armstrong,et al.  Time to treatment and the impact of a physician on prehospital management of acute ST elevation myocardial infarction: insights from the ASSENT-3 PLUS trial , 2005, Heart.

[461]  P. Jüni,et al.  Bivalirudin or Unfractionated Heparin in Acute Coronary Syndromes. , 2015, The New England journal of medicine.

[462]  P. Serruys,et al.  Percutaneous left ventricular assist devices vs. intra-aortic balloon pump counterpulsation for treatment of cardiogenic shock: a meta-analysis of controlled trials. , 2009, European heart journal.

[463]  Sunil V. Rao,et al.  Prevalence, predictors, and in-hospital outcomes of non-infarct artery intervention during primary percutaneous coronary intervention for ST-segment elevation myocardial infarction (from the National Cardiovascular Data Registry). , 2009, The American journal of cardiology.

[464]  Yoshifumi Naka,et al.  Results of the post-U.S. Food and Drug Administration-approval study with a continuous flow left ventricular assist device as a bridge to heart transplantation: a prospective study using the INTERMACS (Interagency Registry for Mechanically Assisted Circulatory Support). , 2011, Journal of the American College of Cardiology.

[465]  S. Bangalore,et al.  Complete Versus Culprit-Only Revascularization for ST-Segment–Elevation Myocardial Infarction and Multivessel Disease: A Meta-Analysis and Trial Sequential Analysis of Randomized Trials , 2015, Circulation. Cardiovascular interventions.

[466]  K. Dickstein,et al.  Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial , 2002, The Lancet.

[467]  M. Sevick,et al.  Medication nonadherence: a diagnosable and treatable medical condition. , 2013, JAMA.

[468]  Deepak L. Bhatt,et al.  Clopidogrel with or without omeprazole in coronary artery disease. , 2010, The New England journal of medicine.

[469]  Philip J. Barter,et al.  Intensive lipid lowering with atorvastatin in patients with stable coronary disease. , 2005, The New England journal of medicine.

[470]  M. Valgimigli,et al.  Duration of dual antiplatelet therapy after drug-eluting stent implantation: will we ever reach a consensus? , 2015, European heart journal.

[471]  S. Stevens,et al.  Ticagrelor vs. clopidogrel in patients with acute coronary syndromes and diabetes: a substudy from the PLATelet inhibition and patient Outcomes (PLATO) trial , 2010, European heart journal.

[472]  G. Niccoli,et al.  Coronary microvascular obstruction in acute myocardial infarction. , 2016, European heart journal.

[473]  M. Rayner,et al.  Cardiovascular disease in Europe: epidemiological update 2016. , 2016, European heart journal.

[474]  A. Chan,et al.  Improved survival associated with pre-hospital triage strategy in a large regional ST-segment elevation myocardial infarction program. , 2012, JACC. Cardiovascular interventions.

[475]  S. Werns.  Dose Comparisons of Clopidogrel and Aspirin in Acute Coronary Syndromes , 2011 .

[476]  W. Peacock,et al.  Morphine and outcomes in acute decompensated heart failure: an ADHERE analysis , 2008, Emergency Medicine Journal.

[477]  R. Haynes,et al.  Interventions for enhancing medication adherence. , 2008, The Cochrane database of systematic reviews.

[478]  Timothy D. Henry,et al.  A Regional System to Provide Timely Access to Percutaneous Coronary Intervention for ST-Elevation Myocardial Infarction , 2007, Circulation.

[479]  C. Nalliah,et al.  Coronary artery reperfusion for ST elevation myocardial infarction is associated with shorter cycle length ventricular tachycardia and fewer spontaneous arrhythmias. , 2014, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[480]  Karen Smith,et al.  Treatment of Comatose Survivors of Out-of-hospital Cardiac Arrest With Induced Hypothermia , 2003 .

[481]  S. Yusuf,et al.  Effects of fondaparinux on mortality and reinfarction in patients with acute ST-segment elevation myocardial infarction: the OASIS-6 randomized trial. , 2006, JAMA.

[482]  S. Yusuf,et al.  Stroke in the TOTAL trial: a randomized trial of routine thrombectomy vs. percutaneous coronary intervention alone in ST elevation myocardial infarction. , 2015, European heart journal.

[483]  C. Terkelsen,et al.  Deferred versus conventional stent implantation in patients with ST-segment elevation myocardial infarction (DANAMI 3-DEFER): an open-label, randomised controlled trial , 2016, The Lancet.

[484]  P. Armstrong,et al.  Incidence and predictors of bleeding events after fibrinolytic therapy with fibrin-specific agents: a comparison of TNK-tPA and rt-PA☆ , 2002 .

[485]  D. Zahger.  Immediate coronary angiography in survivors of out-of-hospital cardiac arrest. , 1997, The New England journal of medicine.

[486]  S. Stevens,et al.  Rescue angioplasty after failed thrombolytic therapy for acute myocardial infarction. , 2005, The New England journal of medicine.

[487]  B. Nallamothu,et al.  Percutaneous coronary intervention versus fibrinolytic therapy in acute myocardial infarction: is timing (almost) everything? , 2003, The American journal of cardiology.

[488]  H. Huikuri,et al.  Sudden death due to cardiac arrhythmias. , 2001, The New England journal of medicine.

[489]  P. Armstrong,et al.  Efficacy and Safety of Tenecteplase in Combination With the Low-Molecular-Weight Heparin Enoxaparin or Unfractionated Heparin in the Prehospital Setting: The Assessment of the Safety and Efficacy of a New Thrombolytic Regimen (ASSENT)-3 PLUS Randomized Trial in Acute Myocardial Infarction , 2003, Circulation.

[490]  E. Omerovic,et al.  Outcomes 1 year after thrombus aspiration for myocardial infarction. , 2014, The New England journal of medicine.

[491]  Deepak L. Bhatt,et al.  Three, six, or twelve months of dual antiplatelet therapy after DES implantation in patients with or without acute coronary syndromes: an individual patient data pairwise and network meta-analysis of six randomized trials and 11 473 patients , 2017, European heart journal.

[492]  L. Bolognese,et al.  RANDOMISED TRIAL OF INTRAVENOUS STREPTOKINASE, ORAL ASPIRIN, BOTH, OR NEITHER AMONG 17 187 CASES OF SUSPECTED ACUTE MYOCARDIAL INFARCTION: ISIS-2 , 1988, The Lancet.

[493]  M. Beahrs,et al.  Very Rapid Treatment of ST-Segment–Elevation Myocardial Infarction: Utilizing Prehospital Electrocardiograms to Bypass the Emergency Department , 2010, Circulation. Cardiovascular quality and outcomes.

[494]  Marco Valgimigli,et al.  Meta-analysis of randomized trials on drug-eluting stents vs. bare-metal stents in patients with acute myocardial infarction. , 2007, European heart journal.

[495]  P. Armstrong,et al.  Primary versus tenecteplase-facilitated percutaneous coronary intervention in patients with ST-segment elevation acute myocardial infarction (ASSENT-4 PCI): randomised trial , 2006, The Lancet.

[496]  K. Bønaa,et al.  Drug-Eluting or Bare-Metal Stents for Coronary Artery Disease. , 2016, The New England journal of medicine.

[497]  C. Bullen,et al.  Electronic cigarettes for smoking cessation and reduction. , 2014, The Cochrane database of systematic reviews.

[498]  Omeed Saghafi.  Intra-aortic Balloon Counterpulsation and Infarct Size in Patients with Acute Anterior Myocardial Infarction without Shock: The CRISP AMI Randomized Trial , 2012 .

[499]  G. Sangiorgi,et al.  A randomised trial of target-vessel versus multi-vessel revascularisation in ST-elevation myocardial infarction: major adverse cardiac events during long-term follow-up , 2009, Heart.

[500]  R. Perera,et al.  Pharmacological interventions for smoking cessation: an overview and network meta-analysis. , 2013, The Cochrane database of systematic reviews.

[501]  Jackson T. Wright,et al.  A Randomized Trial of Intensive versus Standard Blood-Pressure Control. , 2016, The New England journal of medicine.

[502]  J. Gore,et al.  Declining length of hospital stay for acute myocardial infarction and postdischarge outcomes: a community-wide perspective. , 2004, Archives of internal medicine.

[503]  A. Go,et al.  Should the electrocardiogram be used to guide therapy for patients with left bundle-branch block and suspected myocardial infarction? , 1999, JAMA.