Integrated Omic analysis of lung cancer reveals metabolism proteome signatures with prognostic impact
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Paul Taylor | Michael F Moran | Yuhong Wei | Thomas Kislinger | Alex Ignatchenko | Melania Pintilie | Vladimir Ignatchenko | Lei Li | Ming Li | Jiefei Tong | M. Moran | A. Ignatchenko | L. Muthuswamy | Lei Li | T. Kislinger | M. Tsao | F. Shepherd | Geoffrey Liu | Yuhong Wei | Jiefei Tong | N. Pham | M. Pintilie | Chang-Qi Zhu | Wen Zhang | Frances A Shepherd | Geoffrey Liu | Ming Sound Tsao | Ming Li | C. To | N. Yanagawa | Chang-Qi Zhu | Christine To | Nhu-An Pham | Wen Zhang | Dennis Wang | Naoki Yanagawa | Lakshmi Muthuswamy | V. Ignatchenko | Dennis Wang | Paul Taylor
[1] Andreas Bracher,et al. The molecular architecture of the eukaryotic chaperonin TRiC/CCT. , 2012, Structure.
[2] P. Stover,et al. SHMT1 and SHMT2 Are Functionally Redundant in Nuclear De novo Thymidylate Biosynthesis , 2009, PloS one.
[3] Matthias Mann,et al. High recovery FASP applied to the proteomic analysis of microdissected formalin fixed paraffin embedded cancer tissues retrieves known colon cancer markers. , 2011, Journal of proteome research.
[4] Sharon J. Diskin,et al. Adjustment of genomic waves in signal intensities from whole-genome SNP genotyping platforms , 2008, Nucleic acids research.
[5] Gordon B. Mills,et al. Derailed endocytosis: an emerging feature of cancer , 2008, Nature Reviews Cancer.
[6] V. Denis,et al. Overexpression of phosphoserine aminotransferase PSAT1 stimulates cell growth and increases chemoresistance of colon cancer cells , 2008, Molecular Cancer.
[7] Aik Choon Tan,et al. Patient-derived tumour xenografts as models for oncology drug development , 2012, Nature Reviews Clinical Oncology.
[8] S. Gygi,et al. Correlation between Protein and mRNA Abundance in Yeast , 1999, Molecular and Cellular Biology.
[9] G. Parmigiani,et al. Design and analysis issues in genome-wide somatic mutation studies of cancer. , 2009, Genomics.
[10] M. Yaffe,et al. The t-complex polypeptide 1 complex is a chaperonin for tubulin and actin in vivo. , 1993, Proceedings of the National Academy of Sciences of the United States of America.
[11] R. Finley,et al. Oxygen-dependent expression of cytochrome c oxidase subunit 4-2 gene expression is mediated by transcription factors RBPJ, CXXC5 and CHCHD2 , 2013, Nucleic acids research.
[12] Christian M. Metallo,et al. Metabolic pathway alterations that support cell proliferation. , 2011, Cold Spring Harbor symposia on quantitative biology.
[13] Mark T. W. Ebbert,et al. Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes , 2011, Nature Medicine.
[14] M. Moran,et al. Primary tumor xenografts of human lung adeno and squamous cell carcinoma express distinct proteomic signatures. , 2011, Journal of proteome research.
[15] Pan Du,et al. lumi: a pipeline for processing Illumina microarray , 2008, Bioinform..
[16] L. Meyer,et al. Treatment of acute leukemia with amethopterin (4-amino, 10-methyl pteroyl glutamic acid). , 1950, Acta haematologica.
[17] P. Stover,et al. Serine Hydroxymethyltransferase Anchors de Novo Thymidylate Synthesis Pathway to Nuclear Lamina for DNA Synthesis* , 2012, The Journal of Biological Chemistry.
[18] Joshua F. McMichael,et al. Genome Remodeling in a Basal-like Breast Cancer Metastasis and Xenograft , 2010, Nature.
[19] Andrew Menzies,et al. The patterns and dynamics of genomic instability in metastatic pancreatic cancer , 2010, Nature.
[20] M. Mann,et al. Ultra High Resolution Linear Ion Trap Orbitrap Mass Spectrometer (Orbitrap Elite) Facilitates Top Down LC MS/MS and Versatile Peptide Fragmentation Modes* , 2011, Molecular & Cellular Proteomics.
[21] G. Scagliotti,et al. Treatment-by-Histology Interaction Analyses in Three Phase III Trials Show Superiority of Pemetrexed in Nonsquamous Non-small Cell Lung Cancer , 2011, Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer.
[22] Michael Levitt,et al. Subunit order of eukaryotic TRiC/CCT chaperonin by cross-linking, mass spectrometry, and combinatorial homology modeling , 2012, Proceedings of the National Academy of Sciences.
[23] G I Murray,et al. Characterization and over‐expression of chaperonin t‐complex proteins in colorectal cancer , 2006, The Journal of pathology.
[24] M. Mann,et al. Andromeda: a peptide search engine integrated into the MaxQuant environment. , 2011, Journal of proteome research.
[25] Roland Nilsson,et al. A Computational Screen for Regulators of Oxidative Phosphorylation Implicates SLIRP in Mitochondrial RNA Homeostasis , 2009, PLoS genetics.
[26] Somasekar Seshagiri,et al. Comparative oncogenomics identifies PSMB4 and SHMT2 as potential cancer driver genes. , 2014, Cancer research.
[27] Steven J. M. Jones,et al. Comprehensive genomic characterization of squamous cell lung cancers , 2012, Nature.
[28] D. Jayne,et al. Retinoic acid-induced protein 3: identification and characterisation of a novel prognostic colon cancer biomarker. , 2013, European journal of cancer.
[29] 이연수. Functional genomics reveal that the serine synthesis pathway is essential in breast cancer , 2011 .
[30] M. Mann,et al. MaxQuant enables high peptide identification rates, individualized p.p.b.-range mass accuracies and proteome-wide protein quantification , 2008, Nature Biotechnology.
[31] W. Kaelin,et al. Diverse Effects of Mutations in Exon II of the von Hippel-Lindau (VHL) Tumor Suppressor Gene on the Interaction of pVHL with the Cytosolic Chaperonin and pVHL-Dependent Ubiquitin Ligase Activity , 2002, Molecular and Cellular Biology.
[32] K. Kinzler,et al. Cancer genes and the pathways they control , 2004, Nature Medicine.
[33] S. Knuutila,et al. CDK4 is a probable target gene in a novel amplicon at 12q13.3–q14.1 in lung cancer , 2005, Genes, chromosomes & cancer.
[34] Juan R. González,et al. R-Gada: a fast and flexible pipeline for copy number analysis in association studies , 2010, BMC Bioinformatics.
[35] D. Hanahan,et al. Hallmarks of Cancer: The Next Generation , 2011, Cell.
[36] P. Robson,et al. Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis , 2012, Cell.
[37] R. Greenberg,et al. A BRISC-SHMT complex deubiquitinates IFNAR1 and regulates interferon responses. , 2013, Cell reports.
[38] M. Moran,et al. Proteomic profiles of human lung adeno and squamous cell carcinoma using super‐SILAC and label‐free quantification approaches , 2014, Proteomics.
[39] Ru Wei,et al. The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth , 2008, Nature.
[40] Robert J. Schumacher,et al. Maturation of Human Cyclin E Requires the Function of Eukaryotic Chaperonin CCT , 1998, Molecular and Cellular Biology.
[41] Allen Waziri,et al. Gefitinib selectively inhibits tumor cell migration in EGFR-amplified human glioblastoma. , 2013, Neuro-oncology.
[42] Andreas Bracher,et al. Molecular chaperones in protein folding and proteostasis , 2011, Nature.
[43] Benjamin J. Raphael,et al. Mutational landscape and significance across 12 major cancer types , 2013, Nature.
[44] L. Toledo-Sherman,et al. New targets for an old drug , 2004, Clinical Proteomics.
[45] Zhandong Liu,et al. Serine catabolism regulates mitochondrial redox control during hypoxia. , 2014, Cancer discovery.
[46] E. Lander,et al. Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma , 2007, Proceedings of the National Academy of Sciences.
[47] B. Fridley,et al. Serine hydroxymethyltransferase 1 and 2: gene sequence variation and functional genomic characterization , 2012, Journal of neurochemistry.
[48] Igor Jurisica,et al. Prognostic gene signatures for non-small-cell lung cancer , 2009, Proceedings of the National Academy of Sciences.
[49] Derek Y. Chiang,et al. The landscape of somatic copy-number alteration across human cancers , 2010, Nature.
[50] Gregory Stephanopoulos,et al. Amplification of phosphoglycerate dehydrogenase diverts glycolytic flux and contributes to oncogenesis , 2012, BMC Proceedings.
[51] N. Shah,et al. Glycine Decarboxylase Activity Drives Non-Small Cell Lung Cancer Tumor-Initiating Cells and Tumorigenesis , 2012 .
[52] M. Mann,et al. Extensive quantitative remodeling of the proteome between normal colon tissue and adenocarcinoma , 2012, Molecular systems biology.
[53] T. Pan,et al. Overexpression of initiator methionine tRNA leads to global reprogramming of tRNA expression and increased proliferation in human epithelial cells. , 2013, RNA.
[54] V. Mootha,et al. Metabolic enzyme expression highlights a key role for MTHFD2 and the mitochondrial folate pathway in cancer , 2014, Nature Communications.
[55] P. Massion,et al. In-depth Proteomic Analysis of Nonsmall Cell Lung Cancer to Discover Molecular Targets and Candidate Biomarkers* , 2012, Molecular & Cellular Proteomics.
[56] Johannes Griss,et al. The Proteomics Identifications (PRIDE) database and associated tools: status in 2013 , 2012, Nucleic Acids Res..
[57] Benjamin E. Gross,et al. The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data. , 2012, Cancer discovery.
[58] F. Bossa,et al. In silico and in vitro validation of serine hydroxymethyltransferase as a chemotherapeutic target of the antifolate drug pemetrexed. , 2011, European journal of medicinal chemistry.
[59] E. Barillot,et al. Establishment and Characterization of a Panel of Human Uveal Melanoma Xenografts Derived from Primary and/or Metastatic Tumors , 2010, Clinical Cancer Research.
[60] M. Tsao,et al. The Ability to Form Primary Tumor Xenografts Is Predictive of Increased Risk of Disease Recurrence in Early-Stage Non–Small Cell Lung Cancer , 2010, Clinical Cancer Research.
[61] K. Kinzler,et al. Cancer Genome Landscapes , 2013, Science.
[62] Angela N. Brooks,et al. Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing , 2012, Cell.
[63] R. Williams,et al. Cytoplasmic chaperonin containing TCP-1: structural and functional characterization. , 1997, Biochemistry.
[64] Isabelle Robert,et al. Translational up-regulation of the EGFR by tumor hypoxia provides a nonmutational explanation for its overexpression in human cancer , 2007, Proceedings of the National Academy of Sciences.
[65] K. Suk,et al. Identification of novel cell migration‐promoting genes by a functional genetic screen , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[66] R. Dinarvand,et al. A review of therapeutic challenges and achievements of methotrexate delivery systems for treatment of cancer and rheumatoid arthritis , 2013, Cancer Chemotherapy and Pharmacology.
[67] Alex E. Lash,et al. Gene Expression Omnibus: NCBI gene expression and hybridization array data repository , 2002, Nucleic Acids Res..
[68] David E. Misek,et al. Discordant Protein and mRNA Expression in Lung Adenocarcinomas * , 2002, Molecular & Cellular Proteomics.