Understanding the Urban Pandemic Spreading of COVID-19 with Real World Mobility Data

Facing the worldwide rapid spreading of COVID-19 pandemic, we need to understand its diffusion in the urban environments with heterogeneous population distribution and mobility. However, challenges exist in the choice of proper spatial resolution, integration of mobility data into epidemic modelling, as well as incorporation of unique characteristics of COVID-19. To address these challenges, we build a data-driven epidemic simulator with COVID-19 specific features, which incorporates real-world mobility data capturing the heterogeneity in urban environments. Based on the simulator, we conduct two series of experiments to: (1) estimate the efficacy of different mobility control policies on intervening the epidemic; and (2) study how the heterogeneity of urban mobility affect the spreading process. Extensive results not only highlight the effectiveness of fine-grained targeted mobility control policies, but also uncover different levels of impact of population density and mobility strength on the spreading process. With such capability and demonstrations, our open simulator contributes to a better understanding of the complex spreading process and smarter policies to prevent another pandemic.

[1]  Alexander Grey,et al.  The Mathematical Theory of Infectious Diseases and Its Applications , 1977 .

[2]  Alessandro Vespignani,et al.  influenza A(H1N1): a Monte Carlo likelihood analysis based on , 2009 .

[3]  Yuyi Wang,et al.  Unique epidemiological and clinical features of the emerging 2019 novel coronavirus pneumonia (COVID‐19) implicate special control measures , 2020, Journal of medical virology.

[4]  L. Yang,et al.  Preliminary estimation of the basic reproduction number of novel coronavirus (2019-nCoV) in China, from 2019 to 2020: A data-driven analysis in the early phase of the outbreak , 2020, International Journal of Infectious Diseases.

[5]  Nuno R. Faria,et al.  The effect of human mobility and control measures on the COVID-19 epidemic in China , 2020, Science.

[6]  P. Klepac,et al.  Feasibility of controlling COVID-19 outbreaks by isolation of cases and contacts , 2020, The Lancet Global Health.

[7]  W. O. Kermack,et al.  A contribution to the mathematical theory of epidemics , 1927 .

[8]  Alessandro Vespignani,et al.  Multiscale mobility networks and the spatial spreading of infectious diseases , 2009, Proceedings of the National Academy of Sciences.

[9]  Victoria Ng,et al.  Estimation of COVID-19 outbreak size in Italy , 2020, The Lancet Infectious Diseases.

[10]  G. Leung,et al.  Nowcasting and forecasting the potential domestic and international spread of the 2019-nCoV outbreak originating in Wuhan, China: a modelling study , 2020, The Lancet.

[11]  Jessica T Davis,et al.  The effect of travel restrictions on the spread of the 2019 novel coronavirus (COVID-19) outbreak , 2020, Science.

[12]  L. Allen,et al.  A primer on stochastic epidemic models: Formulation, numerical simulation, and analysis , 2017, Infectious Disease Modelling.

[13]  Alessandro Vespignani,et al.  The role of the airline transportation network in the prediction and predictability of global epidemics , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[14]  Marta C. González,et al.  A universal model for mobility and migration patterns , 2011, Nature.

[15]  Anil Vullikanti,et al.  Using data-driven agent-based models for forecasting emerging infectious diseases. , 2017, Epidemics.

[16]  Fotios Petropoulos,et al.  Forecasting the novel coronavirus COVID-19 , 2020, PloS one.

[17]  Madhav V. Marathe,et al.  EpiSimdemics: An efficient algorithm for simulating the spread of infectious disease over large realistic social networks , 2008, 2008 SC - International Conference for High Performance Computing, Networking, Storage and Analysis.

[18]  Piet Van Mieghem,et al.  Epidemic processes in complex networks , 2014, ArXiv.

[19]  Aravind Srinivasan,et al.  Modelling disease outbreaks in realistic urban social networks , 2004, Nature.