Mechano-Nanoarchitectonics for Bio-Functions at Interfaces

Architecting well-designed interfacial structures is crucial for fabrication of better bio-related devices such as bio-sensors. A dynamic nature of the interfacial structures with appropriate mechanical properties is advantageous for interactions with bio-related substances. In this short review, a new term, mechano-nanoarchitectonics, has been proposed. This terminology represents nanoarchitectonics methodology for formation of functional structures and regulation of their properties with the aid of mechanical processes. An interfacial two-dimensional environment is an ideal medium to connect macroscopic mechanical actions and nanoscale functions. The review starts with rather traditional topics on how to architect biocomponents at interfaces for bio-reactors and bio-sensors, then covers current active research on mechanical control of bio-functions at dynamic interfaces and emerging topics of mechanical control of DNA origami array and cell differentiation control.

[1]  Katsuhiko Ariga,et al.  Materials nanoarchitectonics for environmental remediation and sensing , 2012 .

[2]  Katsuhiko Ariga,et al.  Vortex-aligned fullerene nanowhiskers as a scaffold for orienting cell growth. , 2015, ACS applied materials & interfaces.

[3]  K. Ariga,et al.  Activity and stability of glucose oxidase in molecular films assembled alternately with polyions. , 1999, Journal of bioscience and bioengineering.

[4]  Katsuhiko Ariga,et al.  Highly Ordered 1D Fullerene Crystals for Concurrent Control of Macroscopic Cellular Orientation and Differentiation toward Large‐Scale Tissue Engineering , 2015, Advanced materials.

[5]  Katsuhiko Ariga,et al.  Molecular Recognition of Nucleotides by the Guanidinium Unit at the Surface of Aqueous Micelles and Bilayers. A Comparison of Microscopic and Macroscopic Interfaces , 1996 .

[6]  Katsuhiko Ariga,et al.  A mechanically controlled indicator displacement assay. , 2012, Angewandte Chemie.

[7]  Katsuhiko Ariga,et al.  Mechanochemical Tuning of the Binaphthyl Conformation at the Air-Water Interface. , 2015, Angewandte Chemie.

[8]  Satoshi Murata,et al.  In situ 2D-extraction of DNA wheels by 3D through-solution transport. , 2015, Physical chemistry chemical physics : PCCP.

[9]  Katsuhiko Ariga,et al.  ASSEMBLY OF MULTICOMPONENT PROTEIN FILMS BY MEANS OF ELECTROSTATIC LAYER-BY-LAYER ADSORPTION , 1995 .

[10]  G. G. Stokes.  "J." , 1890, The New Yale Book of Quotations.

[11]  Katsuhiko Ariga,et al.  Mechanical tuning of molecular recognition to discriminate the single-methyl-group difference between thymine and uracil. , 2010, Journal of the American Chemical Society.

[12]  Satoshi Murata,et al.  Supramolecular 1-D polymerization of DNA origami through a dynamic process at the 2-dimensionally confined air-water interface. , 2016, Physical chemistry chemical physics : PCCP.