A multidimensional sensing device for the discrimination of proteins based on manganese-doped ZnS quantum dots.

Lab-on-a-nanoparticle: the triple-channel optical properties of Mn-doped ZnS quantum dots (fluorescence, phosphorescence, and light scattering) are explored to develop a multidimensional sensing device for the discrimination of proteins in a lab-on-a-nanoparticle approach.

[1]  Xiu‐Ping Yan,et al.  Self-assembly of Mn-doped ZnS quantum dots/octa(3-aminopropyl)octasilsequioxane octahydrochloride nanohybrids for optosensing DNA. , 2009, Chemistry.

[2]  M. Snyder,et al.  Protein arrays and microarrays. , 2001, Current opinion in chemical biology.

[3]  S. Thayumanavan,et al.  Disassembly of noncovalent amphiphilic polymers with proteins and utility in pattern sensing. , 2008, Journal of the American Chemical Society.

[4]  D. Guldi,et al.  Conjugating luminescent CdTe quantum dots with biomolecules. , 2008, The journal of physical chemistry. B.

[5]  Vincent M Rotello,et al.  Detection and identification of proteins using nanoparticle-fluorescent polymer 'chemical nose' sensors. , 2007, Nature nanotechnology.

[6]  Janelle L. Coutts,et al.  A one-step highly sensitive method for DNA detection using dynamic light scattering. , 2008, Journal of the American Chemical Society.

[7]  I. Willner,et al.  Semiconductor quantum dots for bioanalysis. , 2008, Angewandte Chemie.

[8]  H. Rehage,et al.  Dynamic light-scattering analysis of the electrostatic interaction of hexahistidine-tagged cytochrome P450 enzyme with semiconductor quantum dots. , 2006, Chemphyschem : a European journal of chemical physics and physical chemistry.

[9]  Vincent M. Rotello,et al.  Enzyme-amplified array sensing of proteins in solution and in biofluids. , 2010, Journal of the American Chemical Society.

[10]  S. Nock,et al.  Recent developments in protein microarray technology. , 2003, Angewandte Chemie.

[11]  Y. Taes,et al.  Direct CdTe quantum-dot-based fluorescence imaging of human serum proteins. , 2010, Small.

[12]  D. Gamelin,et al.  Doped Semiconductor Nanocrystals: Synthesis, Characterization, Physical Properties, and Applications , 2005 .

[13]  R. Martínez‐Máñez,et al.  Electro-optical triple-channel sensing of metal cations via multiple signalling patterns , 2004 .

[14]  Eduardo García-Breijo,et al.  Multi‐Channel Receptors and Their Relation to Guest Chemosensing and Reconfigurable Molecular Logic Gates , 2005 .

[15]  S. Pal,et al.  Direct conjugation of semiconductor nanocrystals to a globular protein to study protein-folding intermediates. , 2007, The journal of physical chemistry. B.

[16]  D. Wilson,et al.  Protein‐Mikroarray‐Technologie – Prinzipien und neuere Entwicklungen , 2003 .

[17]  Shuo Wu,et al.  Highly sensitive multiresponsive chemosensor for selective detection of Hg2+ in natural water and different monitoring environments. , 2008, Inorganic chemistry.

[18]  C. Hagleitner,et al.  Smart single-chip gas sensor microsystem , 2001, Nature.

[19]  A new method of biomolecular recognition of avidin by light scattering of ZnS:Mn nano‐particles , 2008 .

[20]  Xianwen Kan,et al.  Fluorescence for the determination of protein with functionalized nano-ZnS. , 2002, The Analyst.

[21]  Xiu‐Ping Yan,et al.  Exploring Mn-doped ZnS quantum dots for the room-temperature phosphorescence detection of enoxacin in biological fluids. , 2008, Analytical chemistry.

[22]  Shannon E. Stitzel,et al.  Cross-reactive chemical sensor arrays. , 2000, Chemical reviews.

[23]  Hui Chen,et al.  A one-step homogeneous immunoassay for cancer biomarker detection using gold nanoparticle probes coupled with dynamic light scattering. , 2008, Journal of the American Chemical Society.

[24]  Ying Ma,et al.  A sensitive method for the detection of proteins by high-efficiency fluorescence quenching. , 2005, The Analyst.

[25]  Vincent M Rotello,et al.  Array-based sensing of proteins using conjugated polymers. , 2007, Journal of the American Chemical Society.

[26]  P. Holloway,et al.  Syntheses and applications of Mn-doped II-VI semiconductor nanocrystals. , 2005, Journal of nanoscience and nanotechnology.

[27]  J. Qiao,et al.  Room-temperature phosphorescence chemosensor and Rayleigh scattering chemodosimeter dual-recognition probe for 2,4,6-trinitrotoluene based on manganese-doped ZnS quantum dots. , 2011, Analytical chemistry.

[28]  Wensheng Yang,et al.  Synthesis of water-soluble ZnS : Mn2+ nanocrystals by using mercaptopropionic acid as stabilizer , 2003 .

[29]  Photoluminescence enhancement by coupling of ovalbumin and CdTe quantum dots and its application as protein probe , 2007 .

[30]  Gregory A. Bakken,et al.  Computational methods for the analysis of chemical sensor array data from volatile analytes. , 2000, Chemical reviews.

[31]  Itamar Willner,et al.  Halbleiterquantenpunkte für die Bioanalyse , 2008 .

[32]  Dale M. Willard,et al.  CdSe−ZnS Quantum Dots as Resonance Energy Transfer Donors in a Model Protein−Protein Binding Assay , 2001 .

[33]  G. Bazan,et al.  Conjugated Oligoelectrolyte/ssDNA Aggregates: Self‐Assembled Multicomponent Chromophores for Protein Discrimination , 2009 .

[34]  A. Hierlemann,et al.  Higher-order Chemical Sensing , 2007 .

[35]  D. Margulies,et al.  Protein recognition by an ensemble of fluorescent DNA G-quadruplexes. , 2009, Angewandte Chemie.

[36]  Ricardo Gutierrez-Osuna,et al.  Adaptive microsensor systems. , 2010, Annual review of analytical chemistry.

[37]  Subinoy Rana,et al.  Sensing of proteins in human serum using conjugates of nanoparticles and green fluorescent protein. , 2009, Nature chemistry.

[38]  R. Thakar,et al.  Efficient emission from core/(doped) shell nanoparticles: applications for chemical sensing. , 2007, Nano letters.

[39]  A. Hamilton,et al.  Pattern recognition of proteins based on an array of functionalized porphyrins. , 2006, Journal of the American Chemical Society.

[40]  Thomas A. Kennedy,et al.  Doping semiconductor nanocrystals , 2005, Nature.

[41]  R. Martínez‐Máñez,et al.  Hg2+ and Cu2+ selective detection using a dual channel receptor based on thiopyrylium scaffoldings , 2009 .

[42]  Xiaohu Gao,et al.  Designing multifunctional quantum dots for bioimaging, detection, and drug delivery. , 2010, Chemical Society reviews.

[43]  Pavel Bucek,et al.  A practical approach to optical cross-reactive sensor arrays. , 2010, Chemical Society reviews.

[44]  M. Zhang,et al.  Resonance scattering method for the ultrasensitive determination of peptides using semiconductor nanocrystals. , 2007, Analytica chimica acta.

[45]  Guohong Liu,et al.  Dual-channel sensing of volatile organic compounds with semiconducting nanoparticles. , 2010, Analytical chemistry.

[46]  S. Thayumanavan,et al.  Fluorophore-cored dendrimers for patterns in metalloprotein sensing. , 2009, Chemical communications.

[47]  Michael Schmittel,et al.  Quadruple-channel sensing: a molecular sensor with a single type of receptor site for selective and quantitative multi-ion analysis. , 2007, Angewandte Chemie.

[48]  R. Leblanc,et al.  Effects of DHLA-capped CdSe/ZnS quantum dots on the fibrillation of human serum albumin. , 2010, The journal of physical chemistry. B.

[49]  Laura Baldini,et al.  Pattern-based detection of different proteins using an array of fluorescent protein surface receptors. , 2004, Journal of the American Chemical Society.

[50]  J. McDevitt,et al.  Differential receptors create patterns that distinguish various proteins. , 2005, Angewandte Chemie.

[51]  Itamar Willner,et al.  CdSe/ZnS quantum dots-G-quadruplex/hemin hybrids as optical DNA sensors and aptasensors. , 2010, Analytical chemistry.

[52]  Lauren A Austin,et al.  Dynamic light scattering as a powerful tool for gold nanoparticle bioconjugation and biomolecular binding studies. , 2009, Analytical chemistry.