Longitudinal Study-Based Dementia Prediction for Public Health

The issue of public health in Korea has attracted significant attention given the aging of the country’s population, which has created many types of social problems. The approach proposed in this article aims to address dementia, one of the most significant symptoms of aging and a public health care issue in Korea. The Korean National Health Insurance Service Senior Cohort Database contains personal medical data of every citizen in Korea. There are many different medical history patterns between individuals with dementia and normal controls. The approach used in this study involved examination of personal medical history features from personal disease history, sociodemographic data, and personal health examinations to develop a prediction model. The prediction model used a support-vector machine learning technique to perform a 10-fold cross-validation analysis. The experimental results demonstrated promising performance (80.9% F-measure). The proposed approach supported the significant influence of personal medical history features during an optimal observation period. It is anticipated that a biomedical “big data”-based disease prediction model may assist the diagnosis of any disease more correctly.

[1]  William Stafford Noble,et al.  Support vector machine , 2013 .

[2]  Michael J. Paul,et al.  National and Local Influenza Surveillance through Twitter: An Analysis of the 2012-2013 Influenza Epidemic , 2013, PloS one.

[3]  F. Grodstein,et al.  Education, other socioeconomic indicators, and cognitive function. , 2003, American journal of epidemiology.

[4]  J. Brooke,et al.  Evaluating the Association between Diabetes, Cognitive Decline and Dementia , 2015, International journal of environmental research and public health.

[5]  Michael W. Weiner,et al.  Crowdsourced estimation of cognitive decline and resilience in Alzheimer's disease , 2016, Alzheimer's & Dementia.

[6]  Jeannie-Marie S. Leoutsakos,et al.  Subtle changes in daily functioning predict conversion from normal to mild cognitive impairment or dementia: an analysis of the NACC database , 2016, International Psychogeriatrics.

[7]  Jong-Heon Park,et al.  NHIS Big Data and Health Services - Consolidated Ageing Well Strategy in Korea , 2015, ICT4AgeingWell.

[8]  Y. Guan,et al.  COMPASS: A computational model to predict changes in MMSE scores 24-months after initial assessment of Alzheimer’s disease , 2016, Scientific Reports.

[9]  Baldev Singh,et al.  A review on cholinesterase inhibitors for Alzheimer’s disease , 2013, Archives of pharmacal research.

[10]  M. Arfan Ikram,et al.  Cerebral Perfusion and the Risk of Dementia: A Population-Based Study , 2017, Circulation.

[11]  B. Silbert,et al.  Cognitive decline associated with anesthesia and surgery in the elderly: does this contribute to dementia prevalence? , 2017, Current opinion in psychiatry.

[12]  B. Yoon,et al.  Clinical Predictors for Mild Cognitive Impairment Progression in a Korean Cohort , 2016, Dementia and neurocognitive disorders.

[13]  Byung Sung Kim,et al.  Number of daily antihypertensive drugs and the risk of osteoporotic fractures in older hypertensive adults: National health insurance service - Senior cohort. , 2017, Journal of cardiology.

[14]  H. Soininen,et al.  Recruitment and Baseline Characteristics of Participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)—A Randomized Controlled Lifestyle Trial † , 2014, International journal of environmental research and public health.

[15]  S. Y. Kim,et al.  Economic cost of dementia patients according to the limitation of the activities of daily living in Korea , 2007, International journal of geriatric psychiatry.

[16]  I. Oh,et al.  Calcium-Channel Blockers and Dementia Risk in Older Adults - National Health Insurance Service - Senior Cohort (2002-2013). , 2016, Circulation journal : official journal of the Japanese Circulation Society.

[17]  K. Walters,et al.  Predicting dementia risk in primary care: development and validation of the Dementia Risk Score using routinely collected data , 2016, BMC Medicine.

[18]  U. Habel,et al.  Predicting Stability of Mild Cognitive Impairment (MCI): Findings of a Community Based Sample. , 2017, Current Alzheimer research.

[19]  K. Bhaskaran,et al.  Data Resource Profile: Clinical Practice Research Datalink (CPRD) , 2015, International journal of epidemiology.

[20]  B. Dubois,et al.  Prediction of Alzheimer's Disease Dementia: Data from the GuidAge Prevention Trial. , 2015, Journal of Alzheimer's disease : JAD.

[21]  J. Brust,et al.  Ethanol and Cognition: Indirect Effects, Neurotoxicity and Neuroprotection: A Review , 2010, International journal of environmental research and public health.

[22]  R. Gillum,et al.  Smoking, Cognitive Function and Mortality in a U.S. National Cohort Study , 2011, International journal of environmental research and public health.

[23]  HyangHee Kim,et al.  Association of alcohol drinking with verbal and visuospatial memory impairment in older adults: Clinical Research Center for Dementia of South Korea (CREDOS) study , 2014, International Psychogeriatrics.

[24]  Tomohiro Tanaka Factors predicting perioperative delirium and acute exacerbation of behavioral and psychological symptoms of dementia based on admission data in elderly patients with proximal femoral fracture: A retrospective study , 2016, Geriatrics & gerontology international.

[25]  H. Brodaty,et al.  ALZHEIMER'S DISEASE INTERNATIONAL , 1997, International journal of geriatric psychiatry.

[26]  Martin McKee,et al.  Population ageing and health , 2012, The Lancet.

[27]  G. Kisby,et al.  Is Neurodegenerative Disease a Long-Latency Response to Early-Life Genotoxin Exposure? , 2011, International journal of environmental research and public health.

[28]  H. Amièva,et al.  Usefulness of data from magnetic resonance imaging to improve prediction of dementia: population based cohort study , 2015, BMJ : British Medical Journal.

[29]  Hee-Jin Kang,et al.  Data Resource Profile: The National Health Information Database of the National Health Insurance Service in South Korea , 2016, International journal of epidemiology.

[30]  Maruf Pasha,et al.  Survey of Machine Learning Algorithms for Disease Diagnostic , 2017 .