Prions and prion diseases: Insights from the eye.
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[1] Neena Singh,et al. TGFβ2-Hepcidin Feed-Forward Loop in the Trabecular Meshwork Implicates Iron in Glaucomatous Pathology , 2020, Investigative ophthalmology & visual science.
[2] Yong-Sun Kim,et al. RhoA/ROCK Regulates Prion Pathogenesis by Controlling Connexin 43 Activity , 2020, International journal of molecular sciences.
[3] Qi Zhe Ngoo,et al. Evaluation of Retinal Nerve Fiber Layer Thickness, Electroretinogram and Visual Evoked Potential in Patients with Alzheimer's Disease , 2019, Journal of ophthalmology.
[4] Neena Singh,et al. Local synthesis of hepcidin in the anterior segment of the eye: A novel observation with physiological and pathological implications. , 2019, Experimental eye research.
[5] Neena Singh,et al. Prion protein modulates endothelial to mesenchyme-like transition in trabecular meshwork cells: Implications for primary open angle glaucoma , 2019, Scientific Reports.
[6] B. Chesebro,et al. Microglia are not required for prion-induced retinal photoreceptor degeneration , 2019, Acta Neuropathologica Communications.
[7] C. Sigurdson,et al. Cellular and Molecular Mechanisms of Prion Disease. , 2019, Annual review of pathology.
[8] B. Chesebro,et al. Neuroinflammation, Microglia, and Cell-Association during Prion Disease , 2019, Viruses.
[9] B. Caughey,et al. Prion Seeds Distribute throughout the Eyes of Sporadic Creutzfeldt-Jakob Disease Patients , 2018, mBio.
[10] E. Feinstein,et al. TGF-β-induced IOP elevations are mediated by RhoA in the early but not the late fibrotic phase of open angle glaucoma , 2018, Molecular vision.
[11] E. Pai,et al. The prion protein is embedded in a molecular environment that modulates transforming growth factor β and integrin signaling , 2018, Scientific Reports.
[12] Neena Singh,et al. Prion protein modulates iron transport in the anterior segment: Implications for ocular iron homeostasis and prion transmission , 2018, Experimental eye research.
[13] A. Aguzzi,et al. Prions, prionoids and protein misfolding disorders , 2018, Nature Reviews Genetics.
[14] Neena Singh,et al. Prion protein modulates glucose homeostasis by altering intracellular iron , 2018, Scientific Reports.
[15] T. Stevens,et al. Prion‐like protein aggregates exploit the RHO GTPase to cofilin‐1 signaling pathway to enter cells , 2018, The EMBO journal.
[16] W. Hodge,et al. A Systematic Review Regarding Tonometry and the Transmission of Infectious Diseases , 2018, Journal of clinical medicine research.
[17] Keith L. Black,et al. Optical Coherence Tomography in Alzheimer’s Disease and Other Neurodegenerative Diseases , 2017, Front. Neurol..
[18] S. Hannaoui,et al. Chronic wasting disease: Emerging prions and their potential risk , 2017, PLoS pathogens.
[19] Neena Singh,et al. Prion protein facilitates retinal iron uptake and is cleaved at the β-site: Implications for retinal iron homeostasis in prion disorders , 2017, Scientific Reports.
[20] P. Arosio,et al. Non-Anticoagulant Heparins Are Hepcidin Antagonists for the Treatment of Anemia , 2017, Molecules.
[21] Hyoung-Gon Lee,et al. Regulation of RhoA activity by the cellular prion protein , 2017, Cell Death & Disease.
[22] Gaurang C. Patel,et al. TGFβ2 Induces the Formation of Cross-Linked Actin Networks (CLANs) in Human Trabecular Meshwork Cells Through the Smad and Non-Smad Dependent Pathways , 2017, Investigative ophthalmology & visual science.
[23] G. Legname,et al. In Absence of the Cellular Prion Protein, Alterations in Copper Metabolism and Copper-Dependent Oxidase Activity Affect Iron Distribution , 2016, Front. Neurosci..
[24] Jodi D. Smith,et al. Temporal Resolution of Misfolded Prion Protein Transport, Accumulation, Glial Activation, and Neuronal Death in the Retinas of Mice Inoculated with Scrapie. , 2016, The American journal of pathology.
[25] A. Hata,et al. TGF-β Signaling from Receptors to Smads. , 2016, Cold Spring Harbor perspectives in biology.
[26] Jodie L Babitt,et al. Hepcidin regulation in the anemia of inflammation , 2016, Current opinion in hematology.
[27] T. Ganz,et al. Ironing out Ferroportin. , 2015, Cell metabolism.
[28] Neena Singh,et al. The prion-ZIP connection: From cousins to partners in iron uptake , 2015, Prion.
[29] W. Schulz-Schaeffer,et al. Cellular prion protein directly interacts with and enhances lactate dehydrogenase expression under hypoxic conditions , 2015, Experimental Neurology.
[30] Y. Bailly,et al. Double-Edge Sword of Sustained ROCK Activation in Prion Diseases through Neuritogenesis Defects and Prion Accumulation , 2015, PLoS pathogens.
[31] Claire A. Baker,et al. Circulation of prions within dust on a scrapie affected farm , 2015, Veterinary Research.
[32] D. Richardson,et al. Duodenal Cytochrome b (DCYTB) in Iron Metabolism: An Update on Function and Regulation , 2015, Nutrients.
[33] B. Chesebro,et al. Prion Infection of Mouse Brain Reveals Multiple New Upregulated Genes Involved in Neuroinflammation or Signal Transduction , 2014, Journal of Virology.
[34] C. Haigh,et al. MEK1 transduces the prion protein N2 fragment antioxidant effects , 2014, Cellular and Molecular Life Sciences.
[35] Neena Singh. The Role of Iron in Prion Disease and Other Neurodegenerative Diseases , 2014, PLoS pathogens.
[36] G. Schmitt-Ulms,et al. An emerging role of the cellular prion protein as a modulator of a morphogenetic program underlying epithelial-to-mesenchymal transition , 2014, Front. Cell Dev. Biol..
[37] M. Spino,et al. The oral iron chelator deferiprone protects against systemic iron overload-induced retinal degeneration in hepcidin knockout mice. , 2014, Investigative ophthalmology & visual science.
[38] G. Bloom,et al. Identification of a gene regulatory network associated with prion replication , 2014, The EMBO journal.
[39] Neena Singh,et al. Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities. , 2014, Antioxidants & redox signaling.
[40] G. Millhauser,et al. A New Paradigm for Enzymatic Control of α-Cleavage and β-Cleavage of the Prion Protein* , 2013, The Journal of Biological Chemistry.
[41] J. Launay,et al. Cellular prion protein is required for neuritogenesis: fine-tuning of multiple signaling pathways involved in focal adhesions and actin cytoskeleton dynamics , 2013 .
[42] J. Dunaief,et al. Retinal iron homeostasis in health and disease , 2013, Front. Aging Neurosci..
[43] Barry J Wu,et al. A case of Creutzfeldt-Jakob disease following cataract surgery: sporadic versus iatrogenic cause. , 2013, Connecticut medicine.
[44] K. Hanada,et al. Species-barrier phenomenon in prion transmissibility from a viewpoint of protein science. , 2013, Journal of biochemistry.
[45] V. Martins,et al. High levels of Cellular Prion Protein improve astrocyte development , 2013, FEBS letters.
[46] A. Harris,et al. The role of transforming growth factor β in glaucoma and the therapeutic implications , 2013, British Journal of Ophthalmology.
[47] Neena Singh,et al. Prion protein regulates iron transport by functioning as a ferrireductase. , 2013, Journal of Alzheimer's disease : JAD.
[48] G. Schmitt-Ulms,et al. The ZIP-prion connection , 2012, Prion.
[49] S. Bartelt-Hunt,et al. Occurrence, Transmission, and Zoonotic Potential of Chronic Wasting Disease , 2012, Emerging infectious diseases.
[50] J. Launay,et al. Neuritogenesis: the prion protein controls β1 integrin signaling activity , 2012, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[51] W. Schulz-Schaeffer,et al. Neuroprotective effects of the cellular prion protein in autoimmune optic neuritis. , 2011, The American journal of pathology.
[52] B. Chesebro,et al. Scrapie pathogenesis in brain and retina: Effects of prion protein expression in neurons and astrocytes , 2005, Journal of NeuroVirology.
[53] S. Picaud,et al. Microcebus murinus retina: A new model to assess prion-related neurotoxicity in primates , 2010, Neurobiology of Disease.
[54] S. García-Castiñeiras. Iron, the retina and the lens: a focused review. , 2010, Experimental eye research.
[55] Neena Singh,et al. Redox control of prion and disease pathogenesis. , 2010, Antioxidants & redox signaling.
[56] M. Rasmussen,et al. Fluorescence spectroscopy of the retina for diagnosis of transmissible spongiform encephalopathies. , 2010, Analytical chemistry.
[57] Beat Meier,et al. Prions , 2010 .
[58] G. Hajj,et al. Prion protein and its ligand stress inducible protein 1 regulate astrocyte development , 2009, Glia.
[59] J. Ironside,et al. Risk of Creutzfeldt–Jakob disease transmission by ocular surgery and tissue transplantation , 2009, Eye.
[60] R. Petersen,et al. Prion Protein (PrP) Knock-Out Mice Show Altered Iron Metabolism: A Functional Role for PrP in Iron Uptake and Transport , 2009, PloS one.
[61] Neena Singh,et al. Abnormal Brain Iron Homeostasis in Human and Animal Prion Disorders , 2009, PLoS pathogens.
[62] L. Fleisher,et al. Iron metabolism in the eye: a review. , 2009, Experimental eye research.
[63] A. Curns,et al. Creutzfeldt-Jakob Disease in Recipients of Corneal Transplants , 2008, Cornea.
[64] C. Barnstable,et al. Expression of ZnT and ZIP zinc transporters in the human RPE and their regulation by neurotrophic factors. , 2008, Investigative ophthalmology & visual science.
[65] M. Schachner,et al. Prion Protein Regulates Glutamate-Dependent Lactate Transport of Astrocytes , 2007, The Journal of Neuroscience.
[66] B. Chesebro,et al. Prion Protein Expression Differences in Microglia and Astroglia Influence Scrapie-Induced Neurodegeneration in the Retina and Brain of Transgenic Mice , 2007, Journal of Virology.
[67] S. Jacchieri,et al. Cellular prion protein interaction with vitronectin supports axonal growth and is compensated by integrins , 2007, Journal of Cell Science.
[68] Charlotte Remé,et al. The prion protein is neuroprotective against retinal degeneration in vivo. , 2006, Experimental eye research.
[69] M. Fleming,et al. The Steap proteins are metalloreductases. , 2006, Blood.
[70] A. Aguzzi,et al. Prion infections, blood and transfusions , 2006, Nature Clinical Practice Neurology.
[71] N. Hooper,et al. Reactive Oxygen Species-mediated β-Cleavage of the Prion Protein in the Cellular Response to Oxidative Stress* , 2005, Journal of Biological Chemistry.
[72] J. Ironside,et al. Prion protein accumulation in eyes of patients with sporadic and variant Creutzfeldt-Jakob disease. , 2003, Investigative ophthalmology & visual science.
[73] P. Klöhn,et al. Transmission of prions , 2002, Proceedings of the National Academy of Sciences of the United States of America.
[74] P. Farnsworth,et al. Prion protein expression in mammalian lenses , 2000 .
[75] S. Prusiner,et al. Prion diseases and the BSE crisis. , 1997, Science.
[76] S. Prusiner,et al. Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein , 1992, Nature.