RRTree: Relative-Rate Tests between groups of sequences on a phylogenetic tree

UNLABELLED RRTree is a user-friendly program for comparing substitution rates between lineages of protein or DNA sequences, relative to an outgroup, through relative rate tests. Genetic diversity is taken into account through use of several sequences, and phylogenetic relations are integrated by topological weighting. AVAILABILITY The ANSI C source code of RRTree, and compiled versions for Macintosh, MS-DOS/Windows, SUN Solaris, and CGI, are freely available at http://pbil.univ-lyon1.fr/software/rrtree.html CONTACT marc.robinson@ens-lyon.fr

[1]  Olivier Gascuel,et al.  On the Interpretation of Bootstrap Trees: Appropriate Threshold of Clade Selection and Induced Gain , 1996 .

[2]  Manolo Gouy,et al.  SEAVIEW and PHYLO_WIN: two graphic tools for sequence alignment and molecular phylogeny , 1996, Comput. Appl. Biosci..

[3]  Peng Li,et al.  Relative-Rate Test for Nucleotide Substitutions between Two Lineages , 1992 .

[4]  N. Bianchi,et al.  Evolution of the Zfx and Zfy genes: rates and interdependence between the genes. , 1993, Molecular biology and evolution.

[5]  A. Wilson,et al.  Generation time and genomic evolution in primates. , 1973, Science.

[6]  M. Gouy,et al.  Sensitivity of the relative-rate test to taxonomic sampling. , 1998, Molecular biology and evolution.

[7]  A Rzhetsky,et al.  Phylogenetic test of the molecular clock and linearized trees. , 1995, Molecular biology and evolution.

[8]  M. Gouy,et al.  Inferring phylogenies from DNA sequences of unequal base compositions. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[9]  W. Li,et al.  Evidence for higher rates of nucleotide substitution in rodents than in man. , 1985, Proceedings of the National Academy of Sciences of the United States of America.