A comparative study on the therapeutic effect of TRPV1, TRPA1, and TRPM8 agonists on swallowing dysfunction associated with aging and neurological diseases

Oropharyngeal sensory impairment is a potential target to treat swallowing dysfunction in patients with oropharyngeal dysphagia (OD).

[1]  N. Vilardell,et al.  Spatiotemporal characteristics of the pharyngeal event‐related potential in healthy subjects and older patients with oropharyngeal dysfunction , 2017, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[2]  L. Rofes,et al.  Oropharyngeal and laryngeal sensory innervation in the pathophysiology of swallowing disorders and sensory stimulation treatments , 2016, Annals of the New York Academy of Sciences.

[3]  N. Vilardell,et al.  Neurorehabilitation strategies for poststroke oropharyngeal dysphagia: from compensation to the recovery of swallowing function , 2016, Annals of the New York Academy of Sciences.

[4]  V. Woisard,et al.  Pharyngeal Electrical Stimulation for Treatment of Dysphagia in Subacute Stroke , 2016, Stroke.

[5]  R. Speyer,et al.  Effect of Bolus Viscosity on the Safety and Efficacy of Swallowing and the Kinematics of the Swallow Response in Patients with Oropharyngeal Dysphagia: White Paper by the European Society for Swallowing Disorders (ESSD) , 2016, Dysphagia.

[6]  X. Navarro,et al.  Localization and expression of TRPV1 and TRPA1 in the human oropharynx and larynx , 2016, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[7]  R. Speyer,et al.  Erratum to: Effect of Bolus Viscosity on the Safety and Efficacy of Swallowing and the Kinematics of the Swallow Response in Patients with Oropharyngeal Dysphagia: White Paper by the European Society for Swallowing Disorders (ESSD) , 2016, Dysphagia.

[8]  R. Speyer,et al.  A Comparative Study Between Modified Starch and Xanthan Gum Thickeners in Post-Stroke Oropharyngeal Dysphagia , 2016, Dysphagia.

[9]  R. Shaker,et al.  Dysphagia: current reality and scope of the problem , 2015, Nature Reviews Gastroenterology &Hepatology.

[10]  L. Rofes,et al.  The effects of a xanthan gum‐based thickener on the swallowing function of patients with dysphagia , 2014, Alimentary pharmacology & therapeutics.

[11]  L. Rofes,et al.  Pharmacodynamics of TRPV1 Agonists in a Bioassay Using Human PC-3 Cells , 2014, TheScientificWorldJournal.

[12]  L. Rofes,et al.  Effect of oral piperine on the swallow response of patients with oropharyngeal dysphagia , 2014, Journal of Gastroenterology.

[13]  L. Rofes,et al.  Effect of surface sensory and motor electrical stimulation on chronic poststroke oropharyngeal dysfunction , 2013, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[14]  R. Teasell,et al.  Proof-of-principle pilot study of oropharyngeal air-pulse application in individuals with dysphagia after hemispheric stroke. , 2013, Archives of physical medicine and rehabilitation.

[15]  N. Vilardell,et al.  Post‐stroke dysphagia: progress at last , 2013, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[16]  Michael J. Hammer,et al.  Airway somatosensory deficits and dysphagia in Parkinson's disease. , 2013, Journal of Parkinson's disease.

[17]  L. Rofes,et al.  Natural capsaicinoids improve swallow response in older patients with oropharyngeal dysphagia , 2012, Gut.

[18]  B. Bloem,et al.  Prevalence of oropharyngeal dysphagia in Parkinson's disease: a meta-analysis. , 2012, Parkinsonism & related disorders.

[19]  P. Clavé,et al.  Oropharyngeal dysphagia as a risk factor for malnutrition and lower respiratory tract infection in independently living older persons: a population-based prospective study. , 2012, Age and ageing.

[20]  V. Arreola,et al.  PREVALENCE OF OROPHARYNGEAL DYSPHAGIA AND IMPAIRED SAFETY AND EFFICACY OF SWALLOW IN INDEPENDENTLY LIVING OLDER PERSONS , 2011, Journal of the American Geriatrics Society.

[21]  L. Rofes,et al.  Pathophysiology of oropharyngeal dysphagia in the frail elderly , 2010, Neurogastroenterology and motility : the official journal of the European Gastrointestinal Motility Society.

[22]  J. Rothwell,et al.  Adjunctive functional pharyngeal electrical stimulation reverses swallowing disability after brain lesions. , 2010, Gastroenterology.

[23]  H. Arai,et al.  INTENSIVE STEPWISE METHOD FOR ORAL INTAKE USING A COMBINATION OF TRANSIENT RECEPTOR POTENTIAL STIMULATION AND OLFACTORY STIMULATION INHIBITS THE INCIDENCE OF PNEUMONIA IN DYSPHAGIC OLDER ADULTS , 2010, Journal of the American Geriatrics Society.

[24]  R. Speyer,et al.  Effects of Therapy in Oropharyngeal Dysphagia by Speech and Language Therapists: A Systematic Review , 2009, Dysphagia.

[25]  Viridiana Arreola,et al.  Accuracy of the volume-viscosity swallow test for clinical screening of oropharyngeal dysphagia and aspiration. , 2008, Clinical nutrition.

[26]  C. Pantev,et al.  Functional oropharyngeal sensory disruption interferes with the cortical control of swallowing , 2007, BMC Neuroscience.

[27]  B. Miller,et al.  Dysphagia in patients with frontotemporal lobar dementia. , 2007, Archives of neurology.

[28]  V. Arreola,et al.  The effect of bolus viscosity on swallowing function in neurogenic dysphagia , 2006, Alimentary pharmacology & therapeutics.

[29]  H. Arai,et al.  A Randomized Trial of Olfactory Stimulation Using Black Pepper Oil in Older People with Swallowing Dysfunction , 2006, Journal of the American Geriatrics Society.

[30]  H. Arai,et al.  Effects of menthol on the triggering of the swallowing reflex in elderly patients with dysphagia. , 2006, British journal of clinical pharmacology.

[31]  Mark Speechley,et al.  Dysphagia After Stroke: Incidence, Diagnosis, and Pulmonary Complications , 2005, Stroke.

[32]  Hidetada Sasaki,et al.  Capsaicin Troche for Swallowing Dysfunction in Older People , 2005, Journal of the American Geriatrics Society.

[33]  Hidetada Sasaki,et al.  EFFECT OF TEMPERATURE ON SWALLOWING REFLEX IN ELDERLY PATIENTS WITH ASPIRATION PNEUMONIA , 2004, Journal of the American Geriatrics Society.

[34]  P. Davis,et al.  The effects of cold, touch, and chemical stimulation of the anterior faucial pillar on human swallowing , 2004, Dysphagia.

[35]  Shiao-Chi Wu,et al.  Prevalence of Impaired Swallowing in Institutionalized Older People in Taiwan , 2002, Journal of the American Geriatrics Society.

[36]  I. Cook,et al.  Development and validation of a self-report symptom inventory to assess the severity of oral-pharyngeal dysphagia. , 2000, Gastroenterology.

[37]  J. Robbins,et al.  Comparing Treatment Intensities of Tactile-Thermal Application , 1998, Dysphagia.

[38]  J. Aviv Effects of aging on sensitivity of the pharyngeal and supraglottic areas. , 1997, The American journal of medicine.

[39]  R. Sacco,et al.  Supraglottic and Pharyngeal Sensory Abnormalities in Stroke Patients with Dysphagia , 1996, The Annals of otology, rhinology, and laryngology.

[40]  C. Lazarus,et al.  Effects of a sour bolus on oropharyngeal swallowing measures in patients with neurogenic dysphagia. , 1995, Journal of speech and hearing research.