Fundamentals of Breast Implant Illness and Device Imaging

The past six decades of silicone breast implant history encompass manufacturing secrecy, regulatory laxity, inadequate informed consent, clever advertising, overly simplistic research methodology, diverse and controversial opinions, changing social patterns, safety issues, information ambiguity, speculation, and deception. This review addresses the verifiable clinical, radiological, and pathological aspects of these devices, particularly with regard to silicone bleeding. This information can favorably assist practitioners and radiologists facing diagnostic challenges encountered in patients with silicone breast implants.

[1]  H. Burrell,et al.  Angiosarcoma arising in the capsule of a mammary silicone implant , 2022, Diagnostic cytopathology.

[2]  N. Hallab,et al.  Particulate Debris Released From Breast Implant Surfaces Are Highly Dependent on Implant Type. , 2021, Aesthetic surgery journal.

[3]  E. Fleury,et al.  The Breast Tumor Microenvironment: Could Silicone Breast Implant Elicit Breast Carcinoma? , 2021, Breast cancer.

[4]  E. Fleury Synchronous breast implant associated anaplastic large cell lymphoma (BIA-ALCL) and silicone induced granuloma of breast implant capsule (SIGBIC): What to learn , 2020, Radiology case reports.

[5]  E. Fleury Silicone Induced Granuloma of Breast Implant Capsule (SIGBIC) diagnosis: Breast Magnetic Resonance (BMR) sensitivity to detect silicone bleeding , 2020, PloS one.

[6]  G. Pruijn,et al.  Low molecular weight silicones induce cell death in cultured cells , 2020, Scientific Reports.

[7]  Eduardo de Faria Castro Fleury Clear to cloudy II: radiological perspective of silicone breast implants , 2020, European Journal of Plastic Surgery.

[8]  D. A. Lachmansingh Breast implant illness and psychiatric implications , 2019, Irish Journal of Psychological Medicine.

[9]  Luiz Charles-de-Sá,et al.  Profile of breast augmentation surgery in Brazil , 2019, Revista Brasileira de Cirurgia Plástica (RBCP) – Brazilian Journal of Plastic Sugery.

[10]  Rod J. Rohrich,et al.  'Silicone Implant Illness': Science vs Myth? , 2019, Plastic and reconstructive surgery.

[11]  P. Hedén,et al.  [Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL)]. , 2020, Lakartidningen.

[12]  Y. Shoenfeld,et al.  Silicone breast implants and the risk of autoimmune/rheumatic disorders: a real-world analysis. , 2018, International journal of epidemiology.

[13]  G. D’Alessandro,et al.  Silicone-Induced Granuloma of Breast Implant Capsule (SIGBIC): Histopathology and Radiological Correlation , 2018, Journal of immunology research.

[14]  P. Tansley,et al.  Spontaneous Regression and Resolution of Breast Implant-Associated Anaplastic Large Cell Lymphoma: Implications for Research, Diagnosis and Clinical Management , 2018, Aesthetic Plastic Surgery.

[15]  D. Roveda,et al.  Application of Breast Ultrasound Elastography to Differentiate Intracapsular Collection from Silicone-Induced Granuloma of Breast Implant Capsule Complementarily to Contrast-Enhanced Breast Magnetic Resonance Imaging , 2017, Breast cancer : basic and clinical research.

[16]  A. Brawer Mechanisms of Breast Implant Toxicity: Will the Real Ringmaster Please Stand Up , 2017 .

[17]  A. Afifi,et al.  Breast Implant Illness: Symptoms, Patient Concerns, and the Power of Social Media. , 2017, Plastic and reconstructive surgery.

[18]  Rodrigo Oliveira Seleti,et al.  Breast magnetic resonance imaging: tips for the diagnosis of silicone-induced granuloma of a breast implant capsule (SIGBIC) , 2017, Insights into Imaging.

[19]  C. A. Ferreira,et al.  Silicone-induced granuloma of breast implant capsule (SIGBIC): similarities and differences with anaplastic large cell lymphoma (ALCL) and their differential diagnosis , 2017, Breast cancer.

[20]  A. Brawer Destiny rides again: the reappearance of silicone gel-filled breast implant toxicity , 2017, Lupus.

[21]  H. Dijkman,et al.  Gel Bleed and Rupture of Silicone Breast Implants Investigated by Light-, Electron Microscopy and Energy Dispersive X-ray Analysis of Internal Organs and Nervous Tissue , 2016 .

[22]  Erin M. Taylor,et al.  Clear to Cloudy: Silicone Breast Implants In Vivo , 2014, Aesthetic Plastic Surgery.

[23]  A. U. Daniels Silicone breast implant materials. , 2012, Swiss medical weekly.

[24]  K. Shirouzu,et al.  Angiosarcoma of the breast with silicone granuloma: a case report. , 2009, The Kurume medical journal.

[25]  R. Marsh,et al.  Breast Implants as a Possible Etiology of Epithelioid Hemangioendothelioma and Successful Therapy with Interferon‐α2 , 2005, The breast journal.

[26]  A. Brawer Silicon and matrix macromolecules: new research opportunities for old diseases from analysis of potential mechanisms of breast implant toxicity. , 1998, Medical hypotheses.

[27]  L. Brinton,et al.  Breast implants and cancer. , 1997, Journal of the National Cancer Institute.

[28]  W. Golder,et al.  [Imaging of silicone granuloma of the breast using magnetic resonance tomography]. , 1992, Rontgenpraxis; Zeitschrift fur radiologische Technik.

[29]  J. Gillooley,et al.  Silicone granulomas of the breast. , 1985, New York state journal of medicine.

[30]  R. Šavrin,et al.  Mass lesion of the breast after augmentation mammoplasty. , 1979, Archives of surgery.