The landscape of somatic mutations in Infant MLL rearranged acute lymphoblastic leukemias
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Cheng Cheng | Li Ding | Robert Huether | Guolian Kang | Jinghui Zhang | Thoas Fioretos | Matthew Parker | Susana Raimondi | Heather L. Mulder | Jing Ma | Michael Edmonson | Elaine R Mardis | Michael Rusch | Jared Becksfort | Ching-Hon Pui | John Easton | Lei Wei | Stanley Pounds | Daniel Catchpoole | Yongjin Li | Sheila Shurtleff | Panduka Nagahawatte | Lei Shi | Amanda Rush | Deqing Pei | Gang Wu | Michael C. Rusch | Michael N. Edmonson | R. Wilson | E. Mardis | J. Downing | S. Shurtleff | S. Raimondi | Cheng Cheng | C. Pui | L. Ding | M. Edmonson | A. Gedman | Charles Lu | T. Fioretos | Jing Ma | C. Mullighan | Guangchun Song | J. Easton | Gang Wu | Xiang Chen | A. Andersson | M. Rusch | Panduka Nagahawatte | Jianmin Wang | Lei Wei | Kristy Boggs | H. Mulder | D. Yergeau | Jinghui Zhang | R. Kriwacki | Linda Holmfeldt | J. Becksfort | Bhavin Vadodaria | D. Pei | R. Huether | D. Catchpoole | S. Pounds | Yongjin Li | P. Gupta | J. Nakitandwe | G. Kang | Lei Shi | Richard K Wilson | Xiang Chen | Kristy Boggs | Donald Yergeau | Bhavin Vadodaria | Pankaj Gupta | Guangchun Song | Charles Lu | James R Downing | Charles G Mullighan | Heather Mulder | N. Venn | R. Sutton | T. Gruber | Rosemary Sutton | A. Chetcuti | Richard Kriwacki | Jesper Heldrup | Joy Nakitandwe | Jianmin Wang | J. Dang | J. Heldrup | Jinjun Dang | Tanja A Gruber | Anna K Andersson | Amanda Larson Gedman | Linda Holmfeldt | Debbie Payne-Turner | Jayanthi Manne | Nicola C Venn | Albert Chetcuti | J. Manne | Amanda Rush | Matthew Parker | D. Payne‐Turner | R. Wilson | Deqing Pei
[1] John D. Minna,et al. Activating Mutations of the Noonan Syndrome-Associated SHP2/PTPN11 Gene in Human Solid Tumors and Adult Acute Myelogenous Leukemia , 2004, Cancer Research.
[2] R. Levine,et al. High-throughput sequencing screen reveals novel, transforming RAS mutations in myeloid leukemia patients. , 2009, Blood.
[3] Giovanni Parmigiani,et al. Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma , 2012, Nature Genetics.
[4] Ken Chen,et al. Recurring mutations found by sequencing an acute myeloid leukemia genome. , 2009, The New England journal of medicine.
[5] R. Pieters,et al. A treatment protocol for infants younger than 1 year with acute lymphoblastic leukaemia (Interfant-99): an observational study and a multicentre randomised trial , 2007, The Lancet.
[6] M. Greaves,et al. In utero rearrangements in the trithorax-related oncogene in infant leukaemias , 1993, Nature.
[7] Barry S Taylor,et al. Genomic and biological characterization of exon 4 KRAS mutations in human cancer. , 2010, Cancer research.
[8] R. Gray. A Class of $K$-Sample Tests for Comparing the Cumulative Incidence of a Competing Risk , 1988 .
[9] H. Kantarjian,et al. FLT3 inhibitors in the treatment of acute myeloid leukemia , 2011, Cancer.
[10] Li Ding,et al. The Pediatric Cancer Genome Project , 2012, Nature Genetics.
[11] J. Downing,et al. The der(11)-encoded MLL/AF-4 fusion transcript is consistently detected in t(4;11)(q21;q23)-containing acute lymphoblastic leukemia. , 1994, Blood.
[12] M. D. Boer,et al. The MLL recombinome of acute leukemias , 2006, Leukemia.
[13] N. Heerema,et al. Cytogenetic features of infants less than 12 months of age at diagnosis of acute lymphoblastic leukemia: impact of the 11q23 breakpoint on outcome: a report of the Childrens Cancer Group. , 1994, Blood.
[14] J. Kalbfleisch,et al. The Statistical Analysis of Failure Time Data , 1980 .
[15] H. Berman. The Protein Data Bank: a historical perspective. , 2008, Acta crystallographica. Section A, Foundations of crystallography.
[16] David G Hendrickson,et al. Differential analysis of gene regulation at transcript resolution with RNA-seq , 2012, Nature Biotechnology.
[17] S Rozen,et al. Primer3 on the WWW for general users and for biologist programmers. , 2000, Methods in molecular biology.
[18] R. Pieters,et al. Cytogenetics and outcome of infants with acute lymphoblastic leukemia and absence of MLL rearrangements , 2013, Leukemia.
[19] D. Largaespada,et al. RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia. , 2009, Blood.
[20] Joshua F. McMichael,et al. Genome Remodeling in a Basal-like Breast Cancer Metastasis and Xenograft , 2010, Nature.
[21] R. Houlston,et al. The silent mutational landscape of infant MLL‐AF4 pro‐B acute lymphoblastic leukemia , 2013, Genes, chromosomes & cancer.
[22] N. Miyake,et al. Activated K-Ras protein accelerates human MLL/AF4-induced leukemo-lymphomogenicity in a transgenic mouse model , 2011, Leukemia.
[23] Heather L. Mulder,et al. The landscape of somatic mutations in epigenetic regulators across 1,000 paediatric cancer genomes , 2014, Nature Communications.
[24] M. Loh,et al. Mutations in PTPN11 implicate the SHP-2 phosphatase in leukemogenesis. , 2004, Blood.
[25] Christopher B. Miller,et al. Genome-wide analysis of genetic alterations in acute lymphoblastic leukaemia , 2007, Nature.
[26] M. Greaves,et al. Backtracking leukemia to birth: identification of clonotypic gene fusion sequences in neonatal blood spots. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[27] P. Woll,et al. Clonal variegation and dynamic competition of leukemia-initiating cells in infant acute lymphoblastic leukemia with MLL rearrangement , 2014, Leukemia.
[28] Laurence L. George,et al. The Statistical Analysis of Failure Time Data , 2003, Technometrics.
[29] J. V. van Dongen,et al. Genetic aberrations in paediatric acute leukaemias and implications for management of patients. , 2010, The Lancet. Oncology.
[30] S. Knapp,et al. Targeting bromodomains: epigenetic readers of lysine acetylation , 2014, Nature Reviews Drug Discovery.
[31] R. Stam,et al. Frequencies and prognostic impact of RAS mutations in MLL-rearranged acute lymphoblastic leukemia in infants , 2013, Haematologica.
[32] R. Rosenfeld. Patients , 2012, Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery.
[33] Scott A. Armstrong,et al. MLL translocations, histone modifications and leukaemia stem-cell development , 2007, Nature Reviews Cancer.
[34] Cheng Cheng,et al. Treating childhood acute lymphoblastic leukemia without cranial irradiation. , 2009, The New England journal of medicine.
[35] Li Ding,et al. Somatic Histone H3 Alterations in Paediatric Diffuse Intrinsic Pontine Gliomas and Non-Brainstem Glioblastomas , 2012, Nature Genetics.
[36] R. Steele,et al. Activating K-Ras mutations outwith ‘hotspot’ codons in sporadic colorectal tumours – implications for personalised cancer medicine , 2010, British Journal of Cancer.
[37] W. Delano. The PyMOL Molecular Graphics System , 2002 .
[38] R. Engh,et al. FMS-like tyrosine kinase 3-internal tandem duplication tyrosine kinase inhibitors display a nonoverlapping profile of resistance mutations in vitro. , 2009, Cancer research.
[39] A. Biondi,et al. Implementation of array based whole-genome high-resolution technologies confirms the absence of secondary copy-number alterations in MLL-AF4-positive infant ALL patients , 2011, Leukemia.
[40] W. Hiddemann,et al. Exome sequencing identifies recurring FLT3 N676K mutations in core-binding factor leukemia. , 2012, Blood.
[41] B. Roe,et al. Identification of complex genomic breakpoint junctions in the t(9;11) MLL-AF9 fusion gene in acute leukemia. , 1997, Genes, chromosomes & cancer.
[42] M. Mohammadi,et al. A molecular brake in the kinase hinge region regulates the activity of receptor tyrosine kinases. , 2007, Molecular cell.
[43] Michael C. Rusch,et al. CREST maps somatic structural variation in cancer genomes with base-pair resolution , 2011, Nature Methods.
[44] R. Stone,et al. Clinical resistance to the kinase inhibitor PKC412 in acute myeloid leukemia by mutation of Asn-676 in the FLT3 tyrosine kinase domain. , 2006, Blood.
[45] Matthew W. Wilson,et al. A Novel Retinoblastoma Therapy from Genomic and Epigenetic Analyses , 2011, Nature.
[46] K. Kinzler,et al. A frequent kinase domain mutation that changes the interaction between PI3Kα and the membrane , 2009, Proceedings of the National Academy of Sciences.
[47] F. Lu,et al. The structural basis for autoinhibition of FLT3 by the juxtamembrane domain. , 2004, Molecular cell.
[48] N. Heerema,et al. Abnormalities of chromosome bands 15q13‐15 in childhood acute lymphoblastic leukemia , 2002, Cancer.
[49] C. Pui,et al. Biological and therapeutic aspects of infant leukemia. , 2000, Blood.
[50] T. Dingermann,et al. Secondary mutations in t(4;11) leukemia patients , 2012, Leukemia.
[51] Cheng Cheng,et al. A genomic random interval model for statistical analysis of genomic lesion data , 2013, Bioinform..
[52] Jeremy Fairbank,et al. Historical Perspective , 1987, Do We Really Understand Quantum Mechanics?.
[53] J. S. Sodhi,et al. Prediction and functional analysis of native disorder in proteins from the three kingdoms of life. , 2004, Journal of molecular biology.
[54] Suzanne Schubbert,et al. Hyperactive Ras in developmental disorders and cancer , 2007, Nature Reviews Cancer.
[55] J. Rowley,et al. Chromatin structural elements and chromosomal translocations in leukemia. , 2006, DNA repair.
[56] Jen-Fen Fu,et al. K‐ras mutations and N‐ras mutations in childhood acute leukemias with or without mixed‐lineage leukemia gene rearrangements , 2006, Cancer.
[57] Glenn R Masson,et al. Oncogenic mutations mimic and enhance dynamic events in the natural activation of phosphoinositide 3-kinase p110α (PIK3CA) , 2012, Proceedings of the National Academy of Sciences.
[58] M. Girvin,et al. Mechanism of Constitutive Phosphoinositide 3-Kinase Activation by Oncogenic Mutants of the p85 Regulatory Subunit* , 2005, Journal of Biological Chemistry.
[59] Ken Chen,et al. VarScan: variant detection in massively parallel sequencing of individual and pooled samples , 2009, Bioinform..
[60] C. Taylor,et al. Identification of Mutations in Distinct Regions of p85 Alpha in Urothelial Cancer , 2013, PloS one.
[61] R. Marschalek,et al. Fine structure of translocation breakpoints in leukemic blasts with chromosomal translocation t(4;11): the DNA damage-repair model of translocation , 1998, Oncogene.
[62] B. Peters,et al. Somatic mutations in p85alpha promote tumorigenesis through class IA PI3K activation. , 2009, Cancer cell.
[63] R. Wilson,et al. BreakDancer: An algorithm for high resolution mapping of genomic structural variation , 2009, Nature Methods.
[64] S. Nelson,et al. Identification of somatic and germline mutations using whole exome sequencing of congenital acute lymphoblastic leukemia , 2013, BMC Cancer.
[65] R. Ono,et al. Mixed-lineage-leukemia (MLL) fusion protein collaborates with Ras to induce acute leukemia through aberrant Hox expression and Raf activation , 2009, Leukemia.
[66] J. Downing,et al. Failure of CDKN2A/B (INK4A/B-ARF)-mediated tumor suppression and resistance to targeted therapy in acute lymphoblastic leukemia induced by BCR-ABL. , 2008, Genes & development.
[67] Catherine C. Smith,et al. Activity of ponatinib against clinically-relevant AC220-resistant kinase domain mutants of FLT3-ITD. , 2013, Blood.
[68] Steven A. Roberts,et al. Mutational heterogeneity in cancer and the search for new cancer-associated genes , 2013 .
[69] Dongfang Li,et al. Genome sequencing of 161 Mycobacterium tuberculosis isolates from China identifies genes and intergenic regions associated with drug resistance , 2013, Nature Genetics.
[70] Kiran C. Bobba,et al. The genetic basis of early T-cell precursor acute lymphoblastic leukaemia , 2012, Nature.
[71] Cole Trapnell,et al. Transcript assembly and quantification by RNA-Seq reveals unannotated transcripts and isoform switching during cell differentiation. , 2010, Nature biotechnology.
[72] David L. Wheeler,et al. GenBank , 2015, Nucleic Acids Res..
[73] A. Borkhardt,et al. A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells , 1999, Oncogene.
[74] Elizabeth D. Hutchison. A Working Model , 2007 .
[75] François Stricher,et al. The FoldX web server: an online force field , 2005, Nucleic Acids Res..
[76] Heather L. Mulder,et al. Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas , 2013, Nature Genetics.