Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy
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A. Buchan | Ruoli Chen | M. Wood | M. Xilouri | B. Kessler | L. Hoyte | S. Nagel | M. McMenamin | S. Watt | K. Vekrellis | G. Hadley | M. Papadakis | S. Nagel | Cynthia Wright Drakesmith | G. Tsaknakis | Zonghang Zhao | Ruoli Chen | Simon Nagel | Grigorios Tsaknakis | Suzanne M. Watt | Ruoli Chen | Grigorios Tsaknakis | Suzanne M. Watt | Ruoli Chen
[1] C. Netto,et al. Folic Acid Prevents Behavioral Impairment and Na+,K+-ATPase Inhibition Caused by Neonatal Hypoxia–Ischemia , 2012, Neurochemical Research.
[2] Robert Clarke,et al. Guidelines for the use and interpretation of assays for monitoring autophagy , 2012 .
[3] E. Engleman,et al. Calcium/Calmodulin-dependent Protein Kinase II (CaMKII) Inhibition Induces Neurotoxicity via Dysregulation of Glutamate/Calcium Signaling and Hyperexcitability* , 2012, The Journal of Biological Chemistry.
[4] B. Gabryel,et al. Neuronal autophagy in cerebral ischemia — a potential target for neuroprotective strategies? , 2012, Pharmacological reports : PR.
[5] D. Su,et al. Induction of autophagy contributes to the neuroprotection of nicotinamide phosphoribosyltransferase in cerebral ischemia , 2012, Autophagy.
[6] Y. Gupta,et al. Rapamycin protects against middle cerebral artery occlusion induced focal cerebral ischemia in rats , 2011, Behavioural Brain Research.
[7] A. Ouweland,et al. Characterisation of TSC1 promoter deletions in tuberous sclerosis complex patients , 2011, European Journal of Human Genetics.
[8] Z. Wang,et al. Rapamycin protects heart from ischemia/reperfusion injury independent of autophagy by activating PI3 kinase-Akt pathway and mitochondria K(ATP) channel. , 2010, Die Pharmazie.
[9] Bingren Hu,et al. Autophagy and protein aggregation after brain ischemia , 2010, Journal of neurochemistry.
[10] Sang Gyun Kim,et al. Glucose addiction of TSC null cells is caused by failed mTORC1-dependent balancing of metabolic demand with supply. , 2010, Molecular cell.
[11] Z. Qin,et al. Autophagy activation is associated with neuroprotection in a rat model of focal cerebral ischemic preconditioning , 2010, Autophagy.
[12] Lloyd A Greene,et al. Rapamycin Protects against Neuron Death in In Vitro andIn Vivo Models of Parkinson's Disease , 2010, The Journal of Neuroscience.
[13] Loren J. Martin,et al. Suppression of hippocampal TRPM7 protein prevents delayed neuronal death in brain ischemia , 2009, Nature Neuroscience.
[14] Yong-Gang Xu,et al. RNA interference-mediated downregulation of Beclin1 attenuates cerebral ischemic injury in rats , 2009, Acta Pharmacologica Sinica.
[15] David Park,et al. Abberant α-Synuclein Confers Toxicity to Neurons in Part through Inhibition of Chaperone-Mediated Autophagy , 2009, PloS one.
[16] D. Kwiatkowski,et al. Tuberous Sclerosis Complex Activity Is Required to Control Neuronal Stress Responses in an mTOR-Dependent Manner , 2009, The Journal of Neuroscience.
[17] U. Dirnagl,et al. Preconditioning and tolerance against cerebral ischaemia: from experimental strategies to clinical use , 2009, The Lancet Neurology.
[18] G. Buonocore,et al. Protective role of autophagy in neonatal hypoxia–ischemia induced brain injury , 2008, Neurobiology of Disease.
[19] R. Muschel,et al. Novel MMP-9 Substrates in Cancer Cells Revealed by a Label-free Quantitative Proteomics Approach*S , 2008, Molecular & Cellular Proteomics.
[20] S. Campbell,et al. Inhibition of peripheral TNF can block the malaise associated with CNS inflammatory diseases , 2008, Neurobiology of Disease.
[21] S. Heales,et al. Inactivation of brain mitochondrial Lon protease by peroxynitrite precedes electron transport chain dysfunction , 2008, Neurochemistry International.
[22] Kostas Vekrellis,et al. Wild Type α-Synuclein Is Degraded by Chaperone-mediated Autophagy and Macroautophagy in Neuronal Cells* , 2008, Journal of Biological Chemistry.
[23] N. Shioda,et al. Bis(1-oxy-2-pyridinethiolato)oxovanadium(IV) enhances neurogenesis via phosphatidylinositol 3-kinase/Akt and extracellular signal regulated kinase activation in the hippocampal subgranular zone after mouse focal cerebral ischemia , 2008, Neuroscience.
[24] Feng Qi Han,et al. Neuronal injury in rat model of permanent focal cerebral ischemia is associated with activation of autophagic and lysosomal pathways , 2008, Autophagy.
[25] John L Cleveland,et al. Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes , 2008, Autophagy.
[26] R. Kesner. Behavioral functions of the CA3 subregion of the hippocampus. , 2007, Learning & memory.
[27] O. Sorgenfrei,et al. The functional genome of CA1 and CA3 neurons under native conditions and in response to ischemia , 2007, BMC Genomics.
[28] R. Giffard,et al. Selective Dysfunction of Hippocampal CA1 Astrocytes Contributes to Delayed Neuronal Damage after Transient Forebrain Ischemia , 2007, The Journal of Neuroscience.
[29] Tian-Le Xu,et al. Akt inhibits MLK3/JNK3 signaling by inactivating Rac1: a protective mechanism against ischemic brain injury , 2006, Journal of neurochemistry.
[30] G. Donnan,et al. 1,026 Experimental treatments in acute stroke , 2006, Annals of neurology.
[31] A. Buchan,et al. Prior deafferentation confers long term protection to CA1 against transient forebrain ischemia and sustains GluR2 expression , 2006, Brain Research.
[32] Bernardo L Sabatini,et al. Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2 , 2005, Nature Neuroscience.
[33] S. Ginsberg,et al. Expression profile analysis within the human hippocampus: Comparison of CA1 and CA3 pyramidal neurons , 2005, The Journal of comparative neurology.
[34] Gert Lubec,et al. Limitations of current proteomics technologies. , 2005, Journal of chromatography. A.
[35] N. Stergiopulos,et al. Gelsolin superfamily proteins: key regulators of cellular functions , 2004, Cellular and Molecular Life Sciences CMLS.
[36] E. Lein,et al. Defining a Molecular Atlas of the Hippocampus Using DNA Microarrays and High-Throughput In Situ Hybridization , 2004, The Journal of Neuroscience.
[37] J. Blenis,et al. Tuberous Sclerosis Complex Gene Products, Tuberin and Hamartin, Control mTOR Signaling by Acting as a GTPase-Activating Protein Complex toward Rheb , 2003, Current Biology.
[38] A. Katz,et al. Isoform‐Specific Regulation of Na+,K+‐ATPase Endocytosis and Recruitment to the Plasma Membrane , 2003, Annals of the New York Academy of Sciences.
[39] Gert Lubec,et al. Proteomics in brain research: potentials and limitations , 2003, Progress in Neurobiology.
[40] Á. Almeida,et al. Peroxynitrite Protects Neurons against Nitric Oxide-mediated Apoptosis , 2003, The Journal of Biological Chemistry.
[41] Jian Cai,et al. Proteomic analysis of CA1 and CA3 regions of rat hippocampus and differential susceptibility to intermittent hypoxia , 2002, Journal of neurochemistry.
[42] Daigen Xu,et al. Cleavage of plasma membrane calcium pumps by caspases: a link between apoptosis and necrosis , 2002, Cell Death and Differentiation.
[43] A. Windebank,et al. Plasma membrane calcium ATPase plays a role in reducing Ca2+‐mediated cytotoxicity in PC12 cells , 2001, Journal of neuroscience research.
[44] E. Strehler,et al. Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function. , 1999, Frontiers in bioscience : a journal and virtual library.
[45] A. Buchan,et al. Continuing postischemic neuronal death in CA1: influence of ischemia duration and cytoprotective doses of NBQX and SNX-111 in rats. , 1999, Stroke.
[46] R. Simon,et al. Induction of Caspase-3-Like Protease May Mediate Delayed Neuronal Death in the Hippocampus after Transient Cerebral Ischemia , 1998, The Journal of Neuroscience.
[47] J. Zimmer,et al. Postischemic hyperactivity in the Mongolian gerbil correlates with loss of hippocampal neurons. , 1997, Behavioral neuroscience.
[48] F. Iannotti,et al. Differential Vulnerability of the CA1 and CA3 Subfields of the Hippocampus to Superoxide and Hydroxyl Radicals In Vitro , 1997, Journal of neurochemistry.
[49] R. Simon,et al. Expression of the Apoptosis‐Effector Gene, Bax, Is Up‐Regulated in Vulnerable Hippocampal CA1 Neurons Following Global Ischemia , 1996, Journal of neurochemistry.
[50] F. Sharp,et al. Induction of 70-kDa Heat Shock Protein and hsp70 mRNA following Transient Focal Cerebral Ischemia in the Rat , 1993, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[51] I. Nagano,et al. Distributions of heat shock protein (HSP) 70 and heat shock cognate protein (HSC) 70 mRNAs after transient focal ischemia in rat brain , 1992, Brain Research.
[52] R. D. Schwartz,et al. The use of locomotor activity as a behavioral screen for neuronal damage following transient forebrain ischemia in gerbils , 1991, Neuroscience Letters.
[53] A. Buchan,et al. The four-vessel occlusion rat model: method for complete occlusion of vertebral arteries and control of collateral circulation. , 1988, Stroke.
[54] F. Plum,et al. Delayed hippocampal damage in humans following cardiorespiratory arrest , 1987, Neurology.
[55] Takaaki Kirino,et al. Delayed neuronal death in the gerbil hippocampus following ischemia , 1982, Brain Research.
[56] Anna Velander Gisslén,et al. Reference List , 2006, Mammalian Genome.
[57] P. Chan,et al. Akt/GSK3beta survival signaling is involved in acute brain injury after subarachnoid hemorrhage in rats. , 2006, Stroke.
[58] E. Friauf,et al. A subcellular prefractionation protocol for minute amounts of mammalian cell cultures and tissue , 2005, Proteomics.