Foxo proteins cooperatively control the differentiation of Foxp3+ regulatory T cells

[1]  A. Liston,et al.  Regulatory T Cells , 2011, Methods in Molecular Biology.

[2]  A. Rudensky,et al.  Role of conserved non-coding DNA elements in the Foxp3 gene in regulatory T-cell fate , 2010, Nature.

[3]  M. F. Shannon,et al.  c-Rel is required for the development of thymic Foxp3+ CD4 regulatory T cells , 2009, The Journal of experimental medicine.

[4]  S. Ghosh,et al.  Nuclear factor-kappaB modulates regulatory T cell development by directly regulating expression of Foxp3 transcription factor. , 2009, Immunity.

[5]  M. Greene,et al.  Development of Foxp3(+) regulatory t cells is driven by the c-Rel enhanceosome. , 2009, Immunity.

[6]  Y. Belkaid,et al.  Decrease of Foxp3+ Treg cell number and acquisition of effector cell phenotype during lethal infection. , 2009, Immunity.

[7]  L. Chin,et al.  FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis. , 2009, Cell stem cell.

[8]  Caiying Guo,et al.  T cells require Foxo1 to populate the peripheral lymphoid organs , 2009, European journal of immunology.

[9]  S. Hedrick.  The cunning little vixen: Foxo and the cycle of life and death , 2009, Nature Immunology.

[10]  C. Benoist,et al.  Foxp3+ regulatory T cells: differentiation, specification, subphenotypes , 2009, Nature Immunology.

[11]  P. Worley,et al.  The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. , 2009, Immunity.

[12]  R. Proia,et al.  S1P1 receptor overrides regulatory T cell-mediated immune suppression through Akt-mTOR , 2009, Nature Immunology.

[13]  E. Shevach.  Mechanisms of foxp3+ T regulatory cell-mediated suppression. , 2009, Immunity.

[14]  A. Rudensky,et al.  Control of regulatory T cell lineage commitment and maintenance. , 2009, Immunity.

[15]  M. A. Curotto de Lafaille,et al.  Natural and adaptive foxp3+ regulatory T cells: more of the same or a division of labor? , 2009, Immunity.

[16]  Daniel R. Beisner,et al.  Transcription factor Foxo3 controls the magnitude of T cell immune responses by modulating the function of dendritic cells. , 2009, Nature immunology.

[17]  Daniel J. Campbell,et al.  T-bet controls regulatory T cell homeostasis and function during type-1 inflammation , 2009, Nature Immunology.

[18]  R. Flavell,et al.  An essential role of the Forkhead-box transcription factor Foxo1 in control of T cell homeostasis and tolerance. , 2009, Immunity.

[19]  Daniel R. Beisner,et al.  Foxo1 links homing and survival of naive T cells by regulating L-selectin, CCR7 and interleukin 7 receptor , 2009, Nature Immunology.

[20]  A. Rudensky,et al.  Differentiation of regulatory Foxp3+ T cells in the thymic cortex , 2008, Proceedings of the National Academy of Sciences.

[21]  D. Vignali,et al.  How regulatory T cells work , 2008, Nature Reviews Immunology.

[22]  K. Shokat,et al.  T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR , 2008, Proceedings of the National Academy of Sciences.

[23]  M. Schlissel,et al.  Foxo1 directly regulates the transcription of recombination-activating genes during B cell development , 2008, Nature Immunology.

[24]  T. Nomura,et al.  Regulatory T Cells and Immune Tolerance , 2008, Cell.

[25]  C. Benoist,et al.  The AKT–mTOR axis regulates de novo differentiation of CD4+Foxp3+ cells , 2008, The Journal of experimental medicine.

[26]  A. G. Betz,et al.  Neuropilin-1 Expression on Regulatory T Cells Enhances Their Interactions with Dendritic Cells during Antigen Recognition , 2008, Immunity.

[27]  Qizhi Tang,et al.  The Foxp3+ regulatory T cell: a jack of all trades, master of regulation , 2008, Nature Immunology.

[28]  S. Ghosh,et al.  Shared Principles in NF-κB Signaling , 2008, Cell.

[29]  K. Furuuchi,et al.  Smad3 and NFAT cooperate to induce Foxp3 expression through its enhancer , 2008, Nature Immunology.

[30]  M. Farrar,et al.  Linked T cell receptor and cytokine signaling govern the development of the regulatory T cell repertoire. , 2008, Immunity.

[31]  C. Hsieh,et al.  A two-step process for thymic regulatory T cell development. , 2008, Immunity.

[32]  R. DePinho,et al.  Distinct functions for the transcription factor Foxo1 at various stages of B cell differentiation , 2008, Nature Immunology.

[33]  Christophe Benoist,et al.  Foxp3 transcription-factor-dependent and -independent regulation of the regulatory T cell transcriptional signature. , 2007, Immunity.

[34]  W. Leonard,et al.  CREB/ATF-dependent T cell receptor–induced FoxP3 gene expression: a role for DNA methylation , 2007, The Journal of experimental medicine.

[35]  G. Sen,et al.  A critical role for IRAK4 kinase activity in Toll-like receptor–mediated innate immunity , 2007, The Journal of experimental medicine.

[36]  T. Chatila,et al.  Regulatory T cell development in the absence of functional Foxp3 , 2007, Nature Immunology.

[37]  Vincent C. Manganiello,et al.  Foxp3-dependent programme of regulatory T-cell differentiation , 2007, Nature.

[38]  Yonghong Xiao,et al.  FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis , 2007, Cell.

[39]  D. Guertin,et al.  Ablation in mice of the mTORC components raptor, rictor, or mLST8 reveals that mTORC2 is required for signaling to Akt-FOXO and PKCalpha, but not S6K1. , 2006, Developmental cell.

[40]  K. Okkenhaug,et al.  Cutting Edge: The Phosphoinositide 3-Kinase p110δ Is Critical for the Function of CD4+CD25+Foxp3+ Regulatory T Cells1 , 2006, The Journal of Immunology.

[41]  D. Sabatini.  mTOR and cancer: insights into a complex relationship , 2006, Nature Reviews Cancer.

[42]  S. Ziegler.  FOXP3: of mice and men. , 2006, Annual review of immunology.

[43]  Apoorva Mandavilli,et al.  Of mice and men , 2006, Nature Medicine.

[44]  M. Nussenzweig,et al.  Inducing and expanding regulatory T cell populations by foreign antigen , 2005, Nature Immunology.

[45]  A. Rudensky,et al.  Regulatory T cell lineage specification by the forkhead transcription factor foxp3. , 2005, Immunity.

[46]  Jonathan D. Hron,et al.  Regulation of NF-kappaB, Th activation, and autoinflammation by the forkhead transcription factor Foxo3a. , 2004, Immunity.

[47]  S. Zheng,et al.  Natural and Induced CD4+CD25+ Cells Educate CD4+CD25− Cells to Develop Suppressive Activity: The Role of IL-2, TGF-β, and IL-101 , 2004, The Journal of Immunology.

[48]  S. Anderson,et al.  Integration of Smad and Forkhead Pathways in the Control of Neuroepithelial and Glioblastoma Cell Proliferation , 2004, Cell.

[49]  Li Li,et al.  Conversion of Peripheral CD4+CD25− Naive T Cells to CD4+CD25+ Regulatory T Cells by TGF-β Induction of Transcription Factor Foxp3 , 2003, The Journal of experimental medicine.

[50]  F. Ramsdell,et al.  An essential role for Scurfin in CD4+CD25+ T regulatory cells , 2003, Nature Immunology.

[51]  A. Rudensky,et al.  Foxp3 programs the development and function of CD4+CD25+ regulatory T cells , 2003, Nature Immunology.

[52]  T. Nomura,et al.  Control of Regulatory T Cell Development by the Transcription Factor Foxp3 , 2002 .

[53]  M. Toda,et al.  Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. , 1995, Journal of immunology.