Interlaboratory Comparison of Ultrasonic Backscatter Coefficient Measurements From 2 to 9 MHz

As are the attenuation coefficient and sound speed, the backscatter coefficient is a fundamental ultrasonic property that has been used to characterize many tissues. Unfortunately, there is currently far less standardization for the ultrasonic backscatter measurement than for the other two, as evidenced by a previous American Institute of Ultrasound in Medicine (AIUM)–sponsored interlaboratory comparison of ultrasonic backscatter, attenuation, and speed measurements (J Ultrasound Med 1999; 18:615–631). To explore reasons for these disparities, the AIUM Endowment for Education and Research recently supported this second interlaboratory comparison, which extends the upper limit of the frequency range from 7 to 9 MHz.

[1]  L. X. Yao,et al.  Backscatter Coefficient Measurements Using a Reference Phantom to Extract Depth-Dependent Instrumentation Factors , 1990, Ultrasonic imaging.

[2]  John M. Reid,et al.  Analysis and measurement of ultrasound backscattering from an ensemble of scatterers excited by sine‐wave bursts , 1973 .

[3]  E. Madsen,et al.  Method of data reduction for accurate determination of acoustic backscatter coefficients. , 1984, The Journal of the Acoustical Society of America.

[4]  William D. O'Brien,et al.  Differentiation and characterization of rat mammary fibroadenomas and 4T1 mouse carcinomas using quantitative ultrasound imaging , 2004, IEEE Transactions on Medical Imaging.

[5]  F. Foster,et al.  Ultrasonic characterization of selected renal tissues. , 1989, Ultrasound in medicine & biology.

[6]  T J Hall,et al.  Measurements of ultrasonic backscatter coefficients in human liver and kidney in vivo. , 1995, The Journal of the Acoustical Society of America.

[7]  David Potter Computational physics , 1973 .

[8]  E L Madsen,et al.  Liquid or solid ultrasonically tissue-mimicking materials with very low scatter. , 1998, Ultrasound in medicine & biology.

[9]  K. Wear Frequency dependence of ultrasonic backscatter from human trabecular bone: theory and experiment. , 1999, The Journal of the Acoustical Society of America.

[10]  William D O'Brien,et al.  Characterization of tissue microstructure using ultrasonic backscatter: theory and technique for optimization using a Gaussian form factor. , 2002, The Journal of the Acoustical Society of America.

[11]  J. G. Miller,et al.  Differentiation between acutely ischemic myocardium and zones of completed infarction in dogs on the basis of frequency-dependent backscatter. , 1989, The Journal of the Acoustical Society of America.

[12]  D J Coleman,et al.  Correlation of ultrasound parameter imaging with microcirculatory patterns in uveal melanomas. , 1997, Ultrasound in medicine & biology.

[13]  L Li,et al.  [Quantitative backscatter imaging]. , 1999, Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi.

[14]  T J Hall,et al.  Identifying acoustic scattering sources in normal renal parenchyma from the anisotropy in acoustic properties. , 1991, Ultrasound in medicine & biology.

[15]  T J Hall,et al.  Identifying acoustic scattering sources in normal renal parenchyma in vivo by varying arterial and ureteral pressures. , 1992, Ultrasound in medicine & biology.

[16]  E L Madsen,et al.  A reusable perfusion supporting tissue-mimicking material for ultrasound hyperthermia phantoms. , 1990, Medical physics.

[17]  H. Schwan,et al.  Biological Engineering , 1970 .

[18]  J.J. Kaufman,et al.  Diffraction correction methods for insertion ultrasound attenuation estimation , 1993, IEEE Transactions on Biomedical Engineering.

[19]  E. Feleppa,et al.  Theoretical framework for spectrum analysis in ultrasonic tissue characterization. , 1983, The Journal of the Acoustical Society of America.

[20]  R. Kuc,et al.  Estimating the Acoustic Attenuation Coefficient Slope for Liver from Reflected Ultrasound Signals , 1979, IEEE Transactions on Sonics and Ultrasonics.

[21]  J. G. Miller,et al.  Changes in myocardial backscatter throughout the cardiac cycle. , 1983, Ultrasonic imaging.

[22]  J. G. Miller,et al.  The extracellular matrix is an important source of ultrasound backscatter from myocardium. , 2000, The Journal of the Acoustical Society of America.

[23]  D. Nicholas,et al.  Evaluation of backscattering coefficients for excised human tissues: Principles and techniques , 1982 .

[24]  J. Faran Sound Scattering by Solid Cylinders and Spheres , 1951 .

[25]  R C Waag,et al.  Normalization of ultrasonic scattering measurements to obtain average differential scattering cross sections for tissues. , 1983, The Journal of the Acoustical Society of America.

[26]  P. Paufler,et al.  Tables of Physical and Chemical Constants , 1997 .

[27]  E J Feleppa,et al.  Comparison of theoretical scattering results and ultrasonic data from clinical liver examinations. , 1988, Ultrasound in medicine & biology.

[28]  W. Marczak,et al.  Water as a standard in the measurements of speed of sound in liquids , 1997 .

[29]  T J Hall,et al.  Parametric Ultrasound Imaging from Backscatter Coefficient Measurements: Image Formation and Interpretation , 1990, Ultrasonic imaging.

[30]  M. O’Donnell,et al.  Quantitative broadband ultrasonic backscatter: An approach to nondestructive evaluation in acoustically inhomogeneous materials , 1981 .

[31]  J. G. Mottley,et al.  The measurement of backscatter coefficient from a broadband pulse-echo system: a new formulation , 1997, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[32]  F. Foster,et al.  Frequency dependence of ultrasound attenuation and backscatter in breast tissue. , 1986, Ultrasound in medicine & biology.

[33]  E L Madsen,et al.  Oil-in-gelatin dispersions for use as ultrasonically tissue-mimicking materials. , 1982, Ultrasound in medicine & biology.

[34]  Haoran Sun,et al.  ULTRASONIC NONDESTRUCTIVE EVALUATION APPLIED TO PROSTATE CANCER DETECTION , 1998 .

[35]  J. G. Miller,et al.  Interlaboratory comparison of ultrasonic backscatter, attenuation, and speed measurements. , 1999, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[36]  V. Reuter,et al.  Typing of prostate tissue by ultrasonic spectrum analysis , 1996, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[37]  E. Madsen,et al.  Tests of backscatter coefficient measurement using broadband pulses , 1993, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[38]  C M Sehgal Quantitative relationship between tissue composition and scattering of ultrasound. , 1993, The Journal of the Acoustical Society of America.

[39]  John M. Reid,et al.  Scattering of Ultrasound by Blood , 1976, IEEE Transactions on Biomedical Engineering.

[40]  F. Dunn,et al.  Ultrasonic Scattering in Biological Tissues , 1992 .

[41]  Robert C. Waag,et al.  Measurements of calf liver ultrasonic differential and total scattering cross sections , 1984 .

[42]  M. Ragozzino Analysis of the error in measurement of ultrasound speed in tissue due to waveform deformation by frequency-dependent attenuation. , 1981, Ultrasonics.

[43]  Bjorn A. J. Angelsen,et al.  A Theoretical Study of the Scattering of Ultrasound from Blood , 1980, IEEE Transactions on Biomedical Engineering.

[44]  A. R. Selfridge,et al.  Approximate Material Properties in Isotropic Materials , 1985, IEEE Transactions on Sonics and Ultrasonics.