Mathematical models for bone density assessment

A decrease in bone strength associated with osteoporosis and resulting increased susceptibility to fracture continue to be one of the critical challenges of aging population. It is estimated that over 200 million people worldwide suffer from these conditions. Due to difficulty in accurate evaluation of a bone loss, novel approaches in assessing bone overall integrity are introduced. These approaches included the use of micro CT scan bone images of mouse which allow to study simulated related bone structure changes and their modelling applying GMM models.

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