Changes in oxidative nucleic acid modifications and inflammation following one-week treatment with the bile acid sequestrant sevelamer: Two randomised, placebo-controlled trials.

[1]  V. Tremaroli,et al.  Glucose‐lowering effects and mechanisms of the bile acid‐sequestering resin sevelamer , 2018, Diabetes, obesity & metabolism.

[2]  Merlin C. Thomas,et al.  Relationship Between Plasma 8‐OH‐Deoxyguanosine and Cardiovascular Disease and Survival in Type 2 Diabetes Mellitus: Results From the ADVANCE Trial , 2018, Journal of the American Heart Association.

[3]  T. Hansen,et al.  Cardiovascular and All-Cause Mortality Risk Associated With Urinary Excretion of 8-oxoGuo, a Biomarker for RNA Oxidation, in Patients With Type 2 Diabetes: A Prospective Cohort Study , 2017, Diabetes Care.

[4]  C. Torp‐Pedersen,et al.  Clarithromycin, trimethoprim, and penicillin and oxidative nucleic acid modifications in humans: randomised, controlled trials , 2017, British journal of clinical pharmacology.

[5]  B. Staels,et al.  Bile acid control of metabolism and inflammation in obesity, type 2 diabetes, dyslipidemia and NAFLD. , 2017 .

[6]  Florence March,et al.  2016 , 2016, Affair of the Heart.

[7]  T. Henriksen,et al.  Simvastatin and oxidative stress in humans: A randomized, double-blinded, placebo-controlled clinical trial , 2016, Redox biology.

[8]  Jianping Cai,et al.  Elevated Levels of Urinary Markers of Oxidative DNA and RNA Damage in Type 2 Diabetes with Complications , 2015, Oxidative medicine and cellular longevity.

[9]  A. Rosengren,et al.  Excess Mortality among Persons with Type 2 Diabetes. , 2015, The New England journal of medicine.

[10]  M. Portero-Otín,et al.  Dietary advanced glycation end products and their role in health and disease. , 2015, Advances in nutrition.

[11]  M. Woodward,et al.  Effects of sevelamer carbonate on advanced glycation end products and antioxidant/pro-oxidant status in patients with diabetic kidney disease. , 2015, Clinical journal of the American Society of Nephrology : CJASN.

[12]  T. Vilsbøll,et al.  Sevelamer in a diabetologist's perspective: a phosphate‐binding resin with glucose‐lowering potential , 2015, Diabetes, obesity & metabolism.

[13]  H. Sies,et al.  Oxidative stress: a concept in redox biology and medicine , 2015, Redox biology.

[14]  Pietro Ghezzi,et al.  Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal , 2014, Proceedings of the National Academy of Sciences.

[15]  P. Nielsen,et al.  Detection and interpretation of 8-oxodG and 8-oxoGua in urine, plasma and cerebrospinal fluid. , 2014, Biochimica et biophysica acta.

[16]  L. Liaudet,et al.  The role of oxidative stress during inflammatory processes , 2013, Biological chemistry.

[17]  P. Bork,et al.  Richness of human gut microbiome correlates with metabolic markers , 2013, Nature.

[18]  Fredrik H. Karlsson,et al.  Gut metagenome in European women with normal, impaired and diabetic glucose control , 2013, Nature.

[19]  A. Tjønneland,et al.  Association between 8-oxo-7,8-dihydro-2′-deoxyguanosine Excretion and Risk of Postmenopausal Breast Cancer: Nested Case–Control Study , 2013, Cancer Epidemiology, Biomarkers & Prevention.

[20]  T. Henriksen,et al.  Association Between Urinary Markers of Nucleic Acid Oxidation and Mortality in Type 2 Diabetes , 2013, Diabetes Care.

[21]  M. Woodward,et al.  Effects of sevelamer on HbA1c, inflammation, and advanced glycation end products in diabetic kidney disease. , 2012, Clinical journal of the American Society of Nephrology : CJASN.

[22]  P. Nielsen,et al.  RNA modifications by oxidation: a novel disease mechanism? , 2012, Free radical biology & medicine.

[23]  T. Henriksen,et al.  Assays for urinary biomarkers of oxidatively damaged nucleic acids , 2012, Free radical research.

[24]  E. S. Stovgaard,et al.  Urinary Markers of Nucleic Acid Oxidation and Long-Term Mortality of Newly Diagnosed Type 2 Diabetic Patients , 2011, Diabetes Care.

[25]  J. Navarro-González,et al.  Effect of phosphate binders on serum inflammatory profile, soluble CD14, and endotoxin levels in hemodialysis patients. , 2011, Clinical journal of the American Society of Nephrology : CJASN.

[26]  F. Kuipers,et al.  Improved glycemic control with colesevelam treatment in patients with type 2 diabetes is not directly associated with changes in bile acid metabolism , 2010, Hepatology.

[27]  R. Pecoits-Filho,et al.  Sevelamer Decreases Systemic Inflammation in Parallel to a Reduction in Endotoxemia , 2010, Blood Purification.

[28]  M. Budoff,et al.  Effects of Sevelamer and Calcium-Based Phosphate Binders on Lipid and Inflammatory Markers in Hemodialysis Patients , 2007, American Journal of Nephrology.

[29]  L. Ferrucci,et al.  Circulating glycotoxins and dietary advanced glycation endproducts: two links to inflammatory response, oxidative stress, and aging. , 2007, The journals of gerontology. Series A, Biological sciences and medical sciences.

[30]  J. Morillas-Ruiz,et al.  The effects of an antioxidant-supplemented beverage on exercise-induced oxidative stress: results from a placebo-controlled double-blind study in cyclists , 2005, European Journal of Applied Physiology.

[31]  K. Wellen,et al.  Inflammation, stress, and diabetes. , 2005, The Journal of clinical investigation.

[32]  P. Raggi,et al.  Potential antiatherogenic and anti-inflammatory properties of sevelamer in maintenance hemodialysis patients. , 2005, American heart journal.

[33]  Jingwen,et al.  Oxidative Stress Mediates Tumor Necrosis Factor-α–Induced Mitochondrial DNA Damage and Dysfunction in Cardiac Myocytes , 2003 .

[34]  A. Takeshita,et al.  Oxidative Stress Mediates Tumor Necrosis Factor-&agr;–Induced Mitochondrial DNA Damage and Dysfunction in Cardiac Myocytes , 2003, Circulation.

[35]  Qiuwei Xu,et al.  Bile acid binding to sevelamer HCl. , 2002, Kidney international.

[36]  S. Moestrup,et al.  Characterization of an enzyme-linked immunosorbent assay for soluble CD163 , 2002, Scandinavian journal of clinical and laboratory investigation.

[37]  G. FitzGerald,et al.  Isoprostanes: Formation, Analysis and Use As Indices of Lipid Peroxidation in Vivo * , 1999, The Journal of Biological Chemistry.

[38]  R. Ramsdell Renagel: a new and different phosphate binder. , 1999, ANNA journal.

[39]  S. Loft,et al.  Oxidative DNA damage after transplantation of the liver and small intestine in pigs. , 1995, Transplantation.

[40]  C. E. Becker The Lipid Research Clinics Coronary Primary Prevention Trial results. I. Reduction in incidence of coronary heart disease. , 1984, JAMA.

[41]  M. Trauner,et al.  Bile acids in regulation of inflammation and immunity: friend or foe? , 2016, Clinical and experimental rheumatology.

[42]  S. Raimondo,et al.  Invariant NKT cells are expanded in peripheral blood but are undetectable in salivary glands of patients with primary Sjögren's syndrome. , 2016, Clinical and experimental rheumatology.

[43]  R Core Team,et al.  R: A language and environment for statistical computing. , 2014 .

[44]  A. Nagano,et al.  Reduction of oxidative stress marker levels by anti-TNF-alpha antibody, infliximab, in patients with rheumatoid arthritis. , 2008, Clinical and experimental rheumatology.

[45]  The Lipid Research Clinics Coronary Primary Prevention Trial results. II. The relationship of reduction in incidence of coronary heart disease to cholesterol lowering. , 1984, JAMA.