ESAT-6 from Mycobacterium tuberculosis Dissociates from Its Putative Chaperone CFP-10 under Acidic Conditions and Exhibits Membrane-Lysing Activity
暂无分享,去创建一个
S. Cole | N. Honoré | W. Jiskoot | R. Brosch | G. Péhau-Arnaudet | M. Fretz | F. Romain | G. Marchal | M. D. de Jonge | D. Bottai | P. Brodin | P. England
[1] Peter J. Peters,et al. M. tuberculosis and M. leprae Translocate from the Phagolysosome to the Cytosol in Myeloid Cells , 2007, Cell.
[2] S. Morris,et al. The ESAT6 protein of Mycobacterium tuberculosis induces apoptosis of macrophages by activating caspase expression , 2007, Cellular microbiology.
[3] Julian Parkhill,et al. Genome plasticity of BCG and impact on vaccine efficacy , 2007, Proceedings of the National Academy of Sciences.
[4] J. Johndrow,et al. The Type I IFN Response to Infection with Mycobacterium tuberculosis Requires ESX-1-Mediated Secretion and Contributes to Pathogenesis1 , 2007, The Journal of Immunology.
[5] T. Kaisho,et al. Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages , 2007, Nature Immunology.
[6] David Eisenberg,et al. A specific secretion system mediates PPE41 transport in pathogenic mycobacteria , 2006, Molecular microbiology.
[7] W. Jacobs,et al. Mycobacteria lacking the RD1 region do not induce necrosis in the lungs of mice lacking interferon‐γ , 2006, Immunology.
[8] E. Brown,et al. C-Terminal Signal Sequence Promotes Virulence Factor Secretion in Mycobacterium tuberculosis , 2006, Science.
[9] S. Grinstein,et al. The ESAT‐6/CFP‐10 secretion system of Mycobacterium marinum modulates phagosome maturation , 2006, Cellular microbiology.
[10] Peter Zipfel,et al. Mycobacterium tuberculosis secreted protein ESAT-6 interacts with the human protein syntenin-1 , 2006, Central European Journal of Biology.
[11] Martin Phillips,et al. Toward the structural genomics of complexes: crystal structure of a PE/PPE protein complex from Mycobacterium tuberculosis. , 2006, Proceedings of the National Academy of Sciences of the United States of America.
[12] A. Arora,et al. Mycobacterium tuberculosis H37Rv ESAT‐6–CFP‐10 complex formation confers thermodynamic and biochemical stability , 2006, The FEBS journal.
[13] R. Heinzen,et al. Coxiella burnetii inhabits a cholesterol‐rich vacuole and influences cellular cholesterol metabolism , 2006, Cellular microbiology.
[14] S. Cole,et al. Dissection of ESAT-6 System 1 of Mycobacterium tuberculosis and Impact on Immunogenicity and Virulence , 2006, Infection and Immunity.
[15] S. Fleischer,et al. Two dimensional thin layer chromatographic separation of polar lipids and determination of phospholipids by phosphorus analysis of spots , 1970, Lipids.
[16] A. Ghaemmaghami,et al. Superior T cell activation by ESAT-6 as compared with the ESAT-6-CFP-10 complex. , 2005, International immunology.
[17] M. Nilges,et al. Functional Analysis of Early Secreted Antigenic Target-6, the Dominant T-cell Antigen of Mycobacterium tuberculosis, Reveals Key Residues Involved in Secretion, Complex Formation, Virulence, and Immunogenicity* , 2005, Journal of Biological Chemistry.
[18] Jim Norman,et al. Structure and function of the complex formed by the tuberculosis virulence factors CFP‐10 and ESAT‐6 , 2005, The EMBO journal.
[19] Liem Nguyen,et al. The Trojan horse: survival tactics of pathogenic mycobacteria in macrophages. , 2005, Trends in cell biology.
[20] F. G. van der Goot,et al. Oiling the key hole , 2005, Molecular microbiology.
[21] D. Collins,et al. Generation of Attenuated Mycobacterium bovis Strains by Signature-Tagged Mutagenesis for Discovery of Novel Vaccine Candidates , 2005, Infection and Immunity.
[22] S. Cole,et al. Influence of ESAT-6 Secretion System 1 (RD1) of Mycobacterium tuberculosis on the Interaction between Mycobacteria and the Host Immune System1 , 2005, The Journal of Immunology.
[23] J. Cox,et al. A Protein Secretion Pathway Critical for Mycobacterium tuberculosis Virulence Is Conserved and Functional in Mycobacterium smegmatis , 2005, Journal of bacteriology.
[24] J. Seelig. Thermodynamics of lipid-peptide interactions. , 2004, Biochimica et biophysica acta.
[25] D. Sherman,et al. Tuberculous Granuloma Formation Is Enhanced by a Mycobacterium Virulence Determinant , 2004, PLoS biology.
[26] S. H. Kaufmann,et al. CFP10 discriminates between nonacetylated and acetylated ESAT‐6 of Mycobacterium tuberculosis by differential interaction , 2004, Proteomics.
[27] J. Engel,et al. A mycobacterial virulence gene cluster extending RD1 is required for cytolysis, bacterial spreading and ESAT‐6 secretion , 2004, Molecular microbiology.
[28] K. Derbyshire,et al. The RD1 virulence locus of Mycobacterium tuberculosis regulates DNA transfer in Mycobacterium smegmatis. , 2004, Proceedings of the National Academy of Sciences of the United States of America.
[29] C. Buchrieser,et al. Macro-array and bioinformatic analyses reveal mycobacterial 'core' genes, variation in the ESAT-6 gene family and new phylogenetic markers for the Mycobacterium tuberculosis complex. , 2004, Microbiology.
[30] D. Sherman,et al. Individual RD1‐region genes are required for export of ESAT‐6/CFP‐10 and for virulence of Mycobacterium tuberculosis , 2004, Molecular microbiology.
[31] J. Killian,et al. Synthetic peptides as models for intrinsic membrane proteins , 2003, FEBS letters.
[32] S. Takeshita,et al. Mycobacterium marinum Escapes from Phagosomes and Is Propelled by Actin-based Motility , 2003, The Journal of experimental medicine.
[33] Christopher M. Sassetti,et al. Genetic requirements for mycobacterial survival during infection , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[34] D. Eisenberg,et al. The primary mechanism of attenuation of bacillus Calmette–Guérin is a loss of secreted lytic function required for invasion of lung interstitial tissue , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[35] S. Raghavan,et al. Acute infection and macrophage subversion by Mycobacterium tuberculosis require a specialized secretion system , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[36] D. Russell. Phagosomes, fatty acids and tuberculosis , 2003, Nature Cell Biology.
[37] S. Cole,et al. Recombinant BCG exporting ESAT-6 confers enhanced protection against tuberculosis , 2003, Nature Medicine.
[38] D. Sherman,et al. Deletion of RD1 from Mycobacterium tuberculosis mimics bacille Calmette-Guérin attenuation. , 2003, The Journal of infectious diseases.
[39] Priscille Brodin,et al. Loss of RD1 contributed to the attenuation of the live tuberculosis vaccines Mycobacterium bovis BCG and Mycobacterium microti , 2002, Molecular microbiology.
[40] S. Cole,et al. Bacterial Artificial Chromosome-Based Comparative Genomic Analysis Identifies Mycobacterium microti as a Natural ESAT-6 Deletion Mutant , 2002, Infection and Immunity.
[41] M. Pallen. The ESAT-6/WXG100 superfamily -- and a new Gram-positive secretion system? , 2002, Trends in microbiology.
[42] S. Gordon,et al. Conclusive Evidence That the Major T-cell Antigens of the Mycobacterium tuberculosis Complex ESAT-6 and CFP-10 Form a Tight, 1:1 Complex and Characterization of the Structural Properties of ESAT-6, CFP-10, and the ESAT-6 CFP-10 Complex IMPLICATIONS FOR PATHOGENESIS AND VIRULENCE* , 2002 .
[43] R. North. Faculty Opinions recommendation of ATP stimulates human macrophages to kill intracellular virulent Mycobacterium tuberculosis via calcium-dependent phagosome-lysosome fusion. , 2001 .
[44] R. Siezen,et al. The ESAT-6 gene cluster of Mycobacterium tuberculosis and other high G+C Gram-positive bacteria , 2001, Genome Biology.
[45] D. Kusner,et al. ATP Stimulates Human Macrophages to Kill Intracellular Virulent Mycobacterium tuberculosis Via Calcium-Dependent Phagosome-Lysosome Fusion1 , 2001, The Journal of Immunology.
[46] M. Schrader,et al. Cholesterol-dependent interaction of syncollin with the membrane of the pancreatic zymogen granule. , 2001, The Biochemical journal.
[47] S. Lightman,et al. ATP-Mediated Killing of Mycobacterium bovis Bacille Calmette-Guérin Within Human Macrophages Is Calcium Dependent and Associated with the Acidification of Mycobacteria-Containing Phagosomes1 , 2001, The Journal of Immunology.
[48] B. Bonev,et al. Structural Analysis of the Protein/Lipid Complexes Associated with Pore Formation by the Bacterial Toxin Pneumolysin* , 2001, The Journal of Biological Chemistry.
[49] J. Pieters,et al. Essential role for cholesterol in entry of mycobacteria into macrophages. , 2000, Science.
[50] S T Cole,et al. Analysis of the proteome of Mycobacterium tuberculosis in silico. , 1999, Tubercle and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease.
[51] R. Veldhuizen,et al. The role of lipids in pulmonary surfactant. , 1998, Biochimica et biophysica acta.
[52] P. Schlesinger,et al. Cytokine activation leads to acidification and increases maturation of Mycobacterium avium-containing phagosomes in murine macrophages. , 1998, Journal of immunology.
[53] G. Mahairas,et al. Molecular analysis of genetic differences between Mycobacterium bovis BCG and virulent M. bovis , 1996, Journal of bacteriology.
[54] B. Bloom,et al. Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages , 1993, Infection and immunity.