Enhanced neural responsiveness to reward associated with obesity in the absence of food‐related stimuli

Obesity has been characterized by alterations in brain structure and function associated with emotion processing and regulation. Particularly, aberrations in food‐related reward processing have been frequently demonstrated in obese subjects. However, it remains unclear whether reward‐associated functional aberrations in obesity are specific for food‐related stimuli or represent a general deficit in reward processing, extending to other stimulus domains. Given the crucial role of rewarding effects in the development of obesity and the ongoing discussion on overlapping neurobiological traits of obesity and psychiatric disorders such as depression and substance‐related disorders, this study aimed to investigate the possibility of altered reward processing in obese subjects to occur in the absence of food‐related stimuli during a monetary reward condition.

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