Discovery of first-in-class multi-target adenosine A2A receptor antagonists-carbonic anhydrase IX and XII inhibitors. 8-Amino-6-aryl-2-phenyl-1,2,4-triazolo [4,3-a]pyrazin-3-one derivatives as new potential antitumor agents.
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C. Supuran | G. Marucci | M. Buccioni | A. Angeli | R. Volpini | A. Nocentini | P. Gratteri | D. D. Ben | Costanza Ceni | D. Catarzi | V. Colotta | F. Varano