Comparative Assessment of Analytical Performance of Conventional Chemistry Analyzer and Modular Cobas 6000 System Using Routine Chemistry Parameters

5 Abstract: In last three decades, as requirement increases with availability of newer technology, automated equipments took over manual and semi-automatic analysis of patients samples. This trend was observed most profoundly at tertiary care hospitals, where faster turnaround time is a patient care necessity. These automation, nonetheless, also provided better reproducibility, precision and accuracy of results; in addition to 24/7 availability of major lab testing panels. In this regard, the present study described the comparative equipment performance evaluation of conventional chemistry analyzer, Hirachi 912 with modular Cobas 6000 (c 501). Blood samples from patients of either gender, n = 70 (Males = 58, female = 42) were collected during Dec 2011 to Dec 2012 for test panel of Urea, Creatinine, ALT, uric acid, sugar and cholesterol. Standard methodologies and principles were used to analyze all parameters on both instruments. Data were compared using regression analysis and statistical significance of P< 0.05. Comparative analysis showed excellent data correlations among all six parameters on both instruments with R regression ranging from 0.8435 to 0.998, depicting the precision 2