Usefulness of the Oximetry Test for the Diagnosis of Sleep Apnea Syndrome in Japan

We evaluated the usefulness of oximetry tests that are frequently used as screening tools for sleep apnea syndrome (SAS) by determining the level of agreement between oximetry test results and polysomnography test (PSG) results. We retrospectively examined 135 patients suspected of having SAS. Although the oximetry desaturation index (DSI) seemed better than the oximetry apnea index in the agreement with the polysomnography respiratory disturbance index (RDI), the criteria of DSI greater than or equal to 15 was not sensitive enough to screen for moderate SAS (PSG-RDI ≥ 20). Multivariate analyses revealing that body mass index (BMI) as well as DSI correlated well with PSG-RDI, we established a new criterion by adding the BMI score (DSI ≥ 15 or BMI ≥ 25), which remarkably improved the sensitivity. This criterion may be useful not only in clinical practice but also in medical checkups for asymptomatic patients, and also suggests that obese patients with sleep disturbance should undergo PSGs, irrespective of the DSI score.

[1]  K. Kubo,et al.  Cephalometric analysis in obese and nonobese patients with obstructive sleep apnea syndrome. , 2003, Chest.

[2]  F. Portier,et al.  Evaluation of home versus laboratory polysomnography in the diagnosis of sleep apnea syndrome. , 2000, American journal of respiratory and critical care medicine.

[3]  T. Young,et al.  The occurrence of sleep-disordered breathing among middle-aged adults. , 1993, The New England journal of medicine.

[4]  M. Kryger,et al.  Mortality and apnea index in obstructive sleep apnea. Experience in 385 male patients. , 1988, Chest.

[5]  Itsik Dvir,et al.  Evaluation of a portable device based on peripheral arterial tone for unattended home sleep studies. , 2003, Chest.

[6]  Daniel J Buysse,et al.  Sleep–Related Breathing Disorders in Adults: Recommendations for Syndrome Definition and Measurement Techniques in Clinical Research , 2000 .

[7]  T. Young,et al.  Longitudinal study of moderate weight change and sleep-disordered breathing. , 2000, JAMA.

[8]  Christian Guilleminault,et al.  A Comparison of Asian and White Patients With Obstructive Sleep Apnea Syndrome , 1999, The Laryngoscope.

[9]  C. Brambilla,et al.  Accuracy of oximetry for detection of respiratory disturbances in sleep apnea syndrome. , 1996, Chest.

[10]  M J Hensley,et al.  A community study of snoring and sleep-disordered breathing. Prevalence. , 1995, American journal of respiratory and critical care medicine.

[11]  C W Whitney,et al.  Sleep-disordered breathing and cardiovascular disease: cross-sectional results of the Sleep Heart Health Study. , 2001, American journal of respiratory and critical care medicine.

[12]  Erry,et al.  Prospective study of the association between sleep-disordered breathing and hypertension. , 2000, The New England journal of medicine.