Synthesis and pharmacological evaluation of a second generation of pyridothiadiazine 1,1-dioxides acting as AMPA potentiators.

[1]  L. Danober,et al.  Design, synthesis, and pharmacology of novel 7-substituted 3,4-dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxides as positive allosteric modulators of AMPA receptors. , 2007, Journal of medicinal chemistry.

[2]  B. Pirotte,et al.  In search of novel AMPA potentiators. , 2006, Recent patents on CNS drug discovery.

[3]  H. Wigström,et al.  Contribution of AMPA and NMDA receptors to early and late phases of LTP in hippocampal slices , 2006, Neuroscience Research.

[4]  M. Black.  Therapeutic potential of positive AMPA modulators and their relationship to AMPA receptor subunits. A review of preclinical data , 2005, Psychopharmacology.

[5]  K. Hashimoto,et al.  Glutamate Hypothesis of Schizophrenia and Approach for Possible Therapeutic Drugs , 2004 .

[6]  P. Tullio,et al.  New trends in the development of positive allosteric modulators of AMPA receptors , 2004 .

[7]  G. Lynch.  AMPA receptor modulators as cognitive enhancers. , 2004, Current opinion in pharmacology.

[8]  R. Dantzer,et al.  Specific modulation of social memory in rats by cholinomimetic and nootropic drugs, by benzodiazepine inverse agonists, but not by psychostimulants , 1989, Psychopharmacology.

[9]  Peter O. Krutzik,et al.  5'-alkyl-benzothiadiazides: a new subgroup of AMPA receptor modulators with improved affinity. , 2002, Bioorganic & medicinal chemistry.

[10]  R. Wightman,et al.  Synthesis of pyrido-1,2,4-thiadiazines related to antihypertensive 1,2,4-benzothiadiazine-1,1-dioxides , 1998 .

[11]  J Delarge,et al.  4H-1,2,4-Pyridothiadiazine 1,1-dioxides and 2,3-dihydro-4H-1,2, 4-pyridothiadiazine 1,1-dioxides chemically related to diazoxide and cyclothiazide as powerful positive allosteric modulators of (R/S)-2-amino-3-(3-hydroxy-5-methylisoxazol-4-yl)propionic acid receptors: design, synthesis, pharmacology, , 1998, Journal of medicinal chemistry.

[12]  P. Tullio,et al.  Synthesis and structural studies of a new class of heterocyclic compounds: 1,2,4-Pyridothiadiazine 1,1-dioxides, pyridyl analogues of 1,2,4-benzothiadiazine 1,1-dioxides , 1995 .

[13]  R. Moquin,et al.  Benzothiadiazine dioxides: A new class of potent angiotensin-II (AT1) receptor antagonists , 1992 .

[14]  D. Baker,et al.  Syntheses of 2-Chloro- and 2-Amino-5-fluoropyridines and Isolation of a Novel Difluoroboryl Imidate , 1989 .

[15]  D. H. Thor,et al.  Social memory of the male laboratory rat. , 1982 .

[16]  F. Walberg,et al.  Does silver impregnate normal and degenerating boutons? A study based on light and electron microscopical observations of the inferior olive. , 1971, Brain research.

[17]  J. H. Boyer,et al.  2,3-ψ-Dinitrosopyridines1 , 1956 .

[18]  R. Mckee,et al.  Pyrido[3,2-d]thiazoles , 1951 .