Intravelar and Extravelar Portions of Soft Palate Muscles in Velic Constrictions: A Three-Dimensional Modeling Study.

Purpose This study predicts and simulates the function and relative contributions of the intravelar and extravelar portions of the levator veli palatini (LVP) and palatoglossus (PG) muscles in velic constrictions. Method A finite element-based model of the 3-dimensional upper airway structures (palate, pharynx, tongue, jaw, maxilla) was implemented, with LVP and PG divided into intravelar and extravelar portions. Simulations were run to investigate the contributions of these muscles in velopharyngeal port (VPP) closure and constriction of the oropharyngeal isthmus (OPI). Results Simulations reveal that the extravelar portion of LVP, though crucial for lifting the palate, is not sufficient to effect VPP closure. Specifically, the characteristic "bulge" appearing in the posterior soft palate during VPP closure ( Pigott, 1969 ; Serrurier & Badin, 2008 ) is found to result from activation of the intravelar portion of LVP. Likewise, the intravelar portion of posterior PG is crucial in bending the "veil" or "traverse" ( Gick, Francis, Klenin, Mizrahi, & Tom, 2013 ) of the velum anteriorly to produce uvular constrictions of the OPI ( Gick et al., 2014 ). Conclusions Simulations support the view that intravelar LVP and PG play significant roles in VPP and OPI constrictions.

[1]  P. Perrier,et al.  A biomechanical model of cardinal vowel production: muscle activations and the impact of gravity on tongue positioning. , 2009, The Journal of the Acoustical Society of America.

[2]  S. Blemker,et al.  A Computational Model of Velopharyngeal Closure for Simulating Cleft Palate Repair , 2015, The Journal of craniofacial surgery.

[3]  A G Hannam,et al.  Dynamic simulation of muscle and articular properties during human wide jaw opening. , 2000, Archives of oral biology.

[4]  D P Kuehn,et al.  Relationships between muscle activity and velar position. , 1982, The Cleft palate journal.

[5]  David A. Berry,et al.  A Finite Element Model of the Soft Palate , 1999 .

[6]  Hui Chen,et al.  Three-dimensional reconstruction of soft palate modeling from subject-specific magnetic resonance imaging data , 2012, Sleep and Breathing.

[7]  Jianwu Dang,et al.  Anatomical considerations on the extrinsic tongue muscles for articulatory modeling , 2013 .

[8]  J. P. Willging,et al.  Velopharyngeal insufficiency , 2003, Current opinion in otolaryngology & head and neck surgery.

[9]  Yohan Payan,et al.  Coupled Biomechanical Modeling of the Face, Jaw, Skull, Tongue, and Hyoid Bone , 2014, 3D Multiscale Physiological Human.

[10]  L E Bilston,et al.  Viscoelastic properties of the tongue and soft palate using MR elastography. , 2011, Journal of biomechanics.

[11]  Yohan Payan,et al.  Coupled hard–soft tissue simulation with contact and constraints applied to jaw–tongue–hyoid dynamics , 2011 .

[12]  Hui Chen,et al.  Speech function of the oropharyngeal isthmus: a modelling study , 2014, Comput. methods Biomech. Biomed. Eng. Imaging Vis..

[13]  J F Lubker,et al.  An electromyographic-cinefluorographic investigation of velar function during normal speech production. , 1968, The Cleft palate journal.

[14]  A. Serrurier,et al.  A three-dimensional articulatory model of the velum and nasopharyngeal wall based on MRI and CT data. , 2008, The Journal of the Acoustical Society of America.

[15]  Khalil Iskarous,et al.  Functional segments in tongue movement , 2004, Clinical linguistics & phonetics.

[16]  P. Pasche,et al.  Treatment of velopharyngeal insufficiency by autologous fat injection , 2010, European Archives of Oto-Rhino-Laryngology.

[17]  Sidney Fels,et al.  FRANK: A Hybrid 3D Biomechanical Model of the Head and Neck , 2017 .

[18]  D. Kuehn,et al.  Anatomical characteristics of palatoglossus and the anterior faucial pillar. , 1978, The Cleft palate journal.

[19]  Scott Moisik,et al.  A comprehensive 3d biomechanically-driven vocal tract model including inverse dynamics for speech research , 2015, INTERSPEECH.

[20]  D P Kuehn,et al.  Histologic study of the normal human adult soft palate. , 1990, The Cleft palate journal.

[21]  Bryan Gick,et al.  The quantal larynx revisited , 2013 .

[22]  M. Birch,et al.  Biomechanical Properties of the Human Soft Palate , 2009, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[23]  Bryan Gick,et al.  The velic traverse: an independent oral articulator? , 2013, The Journal of the Acoustical Society of America.

[24]  D P Kuehn,et al.  The morphology of musculus uvulae. , 1977, The Cleft palate journal.

[25]  André Rigault,et al.  Velopharyngeal Function: An Electromyographic Study , 1972 .

[26]  F Bell-Berti,et al.  An electromyographic study of velopharyngeal function in speech. , 1976, Journal of speech and hearing research.

[27]  E J Seaver,et al.  A cineradiographic and electromyographic investigation of velar positioning in non-nasal speech. , 1980, The Cleft palate journal.

[28]  Jamie L Perry,et al.  Morphology of the Levator Veli Palatini Muscle Using Magnetic Resonance Imaging , 2013, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[29]  K Rajendran,et al.  A Fresh Cadaveric Study of the Paratubal Muscles: Implications for Eustachian Tube Function in Cleft Palate , 1997, Plastic and reconstructive surgery.

[30]  A. Siddiqui,et al.  Imaging of the pharynx and larynx , 2007 .

[31]  M. Miquel,et al.  Finite Element Analysis Animated Simulation of Velopharyngeal Closure , 2012, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[32]  Yohan Payan,et al.  Simulation of dynamic orofacial movements using a constitutive law varying with muscle activation , 2010, Computer methods in biomechanics and biomedical engineering.

[33]  Katherine S. Harris,et al.  Palatoglossus Activity during Nasal/Nonnasal Vowels of Hindi , 1987, Phonetica.

[34]  J. Dang,et al.  Estimation of vocal tract shapes from speech sounds with a physiological articulatory model , 2002, J. Phonetics.

[35]  Masayuki Sawashima,et al.  Velar coarticulation in French: an electromyographic study , 1977 .

[36]  Sidney Fels,et al.  ArtiSynth: A Fast Interactive Biomechanical Modeling Toolkit Combining Multibody and Finite Element Simulation , 2012 .

[37]  Fredericka Bell‐Berti,et al.  Patterns of Palatoglossus Activity and Their Implications for Speech Organization , 1973 .

[38]  Lubker Jf,et al.  An electromyographic-cinefluorographic investigation of velar function during normal speech production. , 1968 .

[39]  D P Kuehn,et al.  Velopharyngeal closure force and levator veli palatini activation levels in varying phonetic contexts. , 1998, Journal of speech, language, and hearing research : JSLHR.

[40]  B C Sommerlad,et al.  Musculus uvulae and levator palati: their anatomical and functional relationship in velopharyngeal closure. , 1985, British journal of plastic surgery.

[41]  B. Fritzell,et al.  The velopharyngeal muscles in speech. An electromyographic and cinéradiographic study. , 1969, Acta oto-laryngologica.

[42]  Jamie L. Perry,et al.  A Computational Model Quantifies the Effect of Anatomical Variability on Velopharyngeal Function. , 2015, Journal of speech, language, and hearing research : JSLHR.

[43]  Pigott Rw.  The nasendoscopic appearance of the normal palato-pharyngeal valve. , 1969 .

[44]  Yohan Payan,et al.  Finite element speaker-specific face model generation for the study of speech production , 2010, Computer methods in biomechanics and biomedical engineering.

[45]  Jamie L Perry,et al.  Sexual Dimorphism of the Levator Veli Palatini Muscle: An Imaging Study , 2014, The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association.

[46]  R. Dalston,et al.  The aerodynamic characteristics of speech produced by normal speakers and cleft palate speakers with adequate velopharyngeal function. , 1990, The Cleft palate journal.