Lethal mutagenesis of HIV with mutagenic nucleoside analogs.
暂无分享,去创建一个
J. Mullins | L. Loeb | J. Essigmann | J. Zhang | J M Essigmann | J I Mullins | L A Loeb | F. Kazazi | K. Rose | F Kazazi | J Zhang | K D Rose | Jue Zhang | Karl D. Rose | Farhad Kazazi
[1] David A. Steinhauer,et al. Mutation Frequencies at Defined Single Codon Sites in Vesicular Stomatitis Virus and Poliovirus Can Be Increased Only Slightly by Chemical Mutagenesis , 1990, Journal of virology.
[2] D. A. Kreutzer,et al. Oxidized, deaminated cytosines are a source of C --> T transitions in vivo. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[3] B. Ames,et al. Endogenous oxidative damage of deoxycytidine in DNA. , 1992, Proceedings of the National Academy of Sciences of the United States of America.
[4] L. Samson,et al. Relative efficiencies of the bacterial, yeast, and human DNA methyltransferases for the repair of O6-methylguanine and O4-methylthymine. Suggestive evidence for O4-methylthymine repair by eukaryotic methyltransferases. , 1991, The Journal of biological chemistry.
[5] L. M. Mansky,et al. Lower in vivo mutation rate of human immunodeficiency virus type 1 than that predicted from the fidelity of purified reverse transcriptase , 1995, Journal of virology.
[6] L. Loeb,et al. Oxidative DNA Damage and Mutagenesis , 1998 .
[7] H. Temin. Evolution of cancer genes as a mutation-driven process. , 1988, Cancer research.
[8] L. Loeb,et al. Reverse chemical mutagenesis: identification of the mutagenic lesions resulting from reactive oxygen species-mediated damage to DNA. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[9] J. Coffin,et al. HIV population dynamics in vivo: implications for genetic variation, pathogenesis, and therapy , 1995, Science.
[10] K Bebenek,et al. The accuracy of reverse transcriptase from HIV-1. , 1988, Science.
[11] L. Loeb,et al. Mutagenic potential of O4-methylthymine in vivo determined by an enzymatic approach to site-specific mutagenesis. , 1986, Proceedings of the National Academy of Sciences of the United States of America.
[12] L. Loeb,et al. Incorporation of the Guanosine Triphosphate Analogs 8-Oxo-dGTP and 8-NH2-dGTP by Reverse Transcriptases and Mammalian DNA Polymerases* , 1997, The Journal of Biological Chemistry.
[13] A. Rodrigo,et al. Genetic subtyping of human immunodeficiency virus using a heteroduplex mobility assay. , 1995, PCR methods and applications.
[14] J. Essigmann,et al. Intrachromosomal probes for mutagenesis by alkylated DNA bases replicated in mammalian cells: a comparison of the mutagenicities of O4-methylthymine and O6-methylguanine in cells with different DNA repair backgrounds. , 1996, Chemical research in toxicology.
[15] M. Eigen. Viral quasi species. , 1993 .
[16] H. Buc,et al. Reverse transcriptases and genomic variability: the accuracy of DNA replication is enzyme specific and sequence dependent. , 1990, The EMBO journal.
[17] B. Chesebro,et al. Development of a sensitive quantitative focal assay for human immunodeficiency virus infectivity , 1988, Journal of virology.
[18] M. Eigen,et al. The origin of genetic information: viruses as models. , 1993, Gene.
[19] J. Swenberg,et al. Differential repair of O6-methylguanine in DNA of rat hepatocytes and nonparenchymal cells , 1980, Nature.
[20] W. Folkman,et al. Evidence for the mutagenic potential of the vinyl chloride induced adduct, N2, 3-etheno-deoxyguanosine, using a site-directed kinetic assay. , 1991, Carcinogenesis.
[21] B. Preston,et al. Mechanisms of retroviral mutation. , 1996, Trends in microbiology.
[22] T. Léveillard,et al. Functional interactions between p53 and the TFIIH complex are affected by tumour‐associated mutations. , 1996, The EMBO journal.
[23] E. Domingo,et al. RNA virus mutations and fitness for survival. , 1997, Annual review of microbiology.
[24] J. Fitzgibbon,et al. A new type of G-->A hypermutation affecting human immunodeficiency virus. , 1993, AIDS research and human retroviruses.
[25] R. S. Foote,et al. Base-pairing properties of O6-methylguanine in template DNA during in vitro DNA replication. , 1984, The Journal of biological chemistry.
[26] Jianping Ding,et al. Locations of anti-AIDS drug binding sites and resistance mutations in the three-dimensional structure of HIV-1 reverse transcriptase. Implications for mechanisms of drug inhibition and resistance. , 1994, Journal of molecular biology.
[27] S. Wain-Hobson,et al. Hypermutagenesis of RNA using human immunodeficiency virus type 1 reverse transcriptase and biased dNTP concentrations. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[28] J. Essigmann,et al. Site-specifically modified oligodeoxynucleotides as probes for the structural and biological effects of DNA-damaging agents. , 1988, Chemical research in toxicology.
[29] R. Montesano,et al. Repair of O4-methyldeoxythymidine residues in DNA by mammalian liver extracts. , 1985, Carcinogenesis.
[30] L. Loeb,et al. Inefficient repair of RNA x DNA hybrids. , 1997, European journal of biochemistry.
[31] A. Perelson,et al. HIV-1 Dynamics in Vivo: Virion Clearance Rate, Infected Cell Life-Span, and Viral Generation Time , 1996, Science.
[32] G. A. van der Marel,et al. Role of nucleotide excision repair in processing of O4-alkylthymines in human cells. , 1994, The Journal of biological chemistry.
[33] L. Loeb,et al. Fidelity of HIV-1 reverse transcriptase. , 1988, Science.
[34] J. Chern,et al. Potentiation of 2'-deoxyguanosine cytotoxicity by a novel inhibitor of purine nucleoside phosphorylase, 8-amino-9-benzylguanine. , 1986, Cancer research.
[35] D. Xing,et al. Purification of a mammalian homologue of Escherichia coli endonuclease III: identification of a bovine pyrimidine hydrate-thymine glycol DNAse/AP lyase by irreversible cross linking to a thymine glycol-containing oligoxynucleotide. , 1996, Biochemistry.
[36] E. Domingo,et al. Pol gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy , 1995, Journal of virology.
[37] R. Cunningham,et al. New substrates for old enzymes. 5-Hydroxy-2'-deoxycytidine and 5-hydroxy-2'-deoxyuridine are substrates for Escherichia coli endonuclease III and formamidopyrimidine DNA N-glycosylase, while 5-hydroxy-2'-deoxyuridine is a substrate for uracil DNA N-glycosylase. , 1994, The Journal of biological chemistry.
[38] M. Eigen,et al. Statistical geometry on sequence space. , 1990, Methods in enzymology.
[39] L. Loeb,et al. Mutagenesis by human immunodeficiency virus reverse transcriptase: incorporation of O6-methyldeoxyguanosine triphosphate. , 1997, Mutation research.
[40] L. Loeb,et al. Mechanisms of mutation by oxidative DNA damage: reduced fidelity of mammalian DNA polymerase beta. , 1993, Biochemistry.
[41] M. Boosalis,et al. DNA polymerase insertion fidelity. Gel assay for site-specific kinetics. , 1987, The Journal of biological chemistry.
[42] Susan S. Wallace,et al. Major oxidative products of cytosine, 5-hydroxycytosine and 5- hydroxyuracil, exhibit sequence context-dependent mispairing in vitro , 1994, Nucleic Acids Res..
[43] F. Grosse,et al. Purification and characterization of two DNA helicases from calf thymus nuclei. , 1991, The Journal of biological chemistry.