This paper proposes an efficient and low complexity power-loading algorithm for MIMO-OFDM downlink based cognitive radio system that maximizes the sum rate of single secondary user (SU) under constraints on the tolerable interference thresholds between secondary user and primary user’s frequency bands and the total transmission power. Our suboptimal algorithm is based on the 2 nd order interference tracking and nulling mechanism to allocate transmission power of the subcarriers among SU’s scheme. The performance of our proposed suboptimal scheme is compared with the performance of the classical power loading algorithms, e.g., water filling, 1 st order interference tracking, nulling, and other suboptimal schemes. Numerical results show that our algorithm has low complexity but obtains a higher channel capacity than that of some previous suboptimal algorithms in some scenarios. We dedicate also that for a given interference threshold, the 2 nd order interference tracking mechanism has dynamic number of nulling position instead fixed number of nulling position.