Chemical occlusion of Rhesus Monkey oviducts with quinacrine.

Different doses of quinacrine in agar solution were instilled into the Fallopian tubes of healthy adult female rhesus monkeys in order to determine its effectiveness in producing tubal occlusion. The concentrations tested were 1% 10% 80% and 100%. The animals were sacrificed and checked for tubal blockade and histological changes at 7 15 30 60 and 100 days after treatment. Tubal blockade was noted at each time interval in all animals treated with 80% or 100% quinacrine.(AUTHORS MODIFIED)