Microwave Reflection and Transmission Measurements for Pulmonary Diagnosis and Monitoring

The potential of using low intensity penetrating microwave energy in diagnosis and monitoring of pulmonary diseases such as edema and emphysema has been investigated theoretically and in selected animal models. These diseases are characterized by changes in total lung water which modify the permittivity and conductivity of the lung tissue, and consequently affect the microwave reflection from or transmission through the lung. Both reflection and transmission measurement techniques have been examined. Animal experiments have indicated changes in microwave reflection with lung water changes. The diagnostic capabilities of transmission measurements have been evaluated experimentally on a phantom model, and theoretically on a planelayered tissue model.

[1]  A. Renzetti,et al.  CORRELATION OF STRUCTURE AND FUNCTION IN CHRONIC PULMONARY EMPHYSEMA. , 1965, The American review of respiratory disease.

[2]  K. White Life and death and medicine. , 1973, Scientific American.

[3]  H. Schwan Electrical properties of tissue and cell suspensions. , 1957, Advances in biological and medical physics.

[4]  R. Forster,et al.  Determination of pulmonary parenchymal tissue volume and pulmonary capillary blood flow in man , 1959 .

[5]  J. B. Hasted,et al.  The Dielectric Properties of Water in Solutions , 1952 .

[6]  A. Depierre,et al.  Quantitative study of parenchyma and small conductive airways in chronic nonspecific lung disease. Use of histologic stereology and bronchial casts. , 1972, Chest.

[7]  N. C. Staub Pulmonary edema. , 1974, Physiological reviews.

[8]  Arthur W. Guy,et al.  Therapeutic applications of electromagnetic power , 1974 .

[9]  Kam Li,et al.  Capacity and Conductivity of Body Tissues at Ultrahigh Frequencies , 1953, Proceedings of the IRE.

[10]  C. R. Merritt,et al.  On Defining the Pulmonary Extravascular Water Volume , 1971, Circulation research.

[11]  A. E. Anderson,et al.  Centrilobular emphysema and panlobular emphysema: two different diseases 1 , 1973, Thorax.

[12]  James C. Lin,et al.  Microwave Measurement of Respiration , 1975 .

[13]  C. Susskind,et al.  Possible use of microwaves in the management of lung disease , 1973 .

[14]  H. F. Cook,et al.  A comparison of the dielectric behaviour of pure water and human blood at microwave frequencies , 1952 .

[15]  M. Sackner,et al.  Diffusing capacity, membrane diffusing capacity, capillary blood volume, pulmonary tissue volume, and cardiac output measured by a rebreathing technique. , 2015, The American review of respiratory disease.

[16]  R. Luepker,et al.  Pulmonary extravascular and intravascular fluid volumes in resting patients. , 1971, The American journal of cardiology.

[17]  A. Guy,et al.  Nonionizing electromagnetic wave effects in biological materials and systems , 1972 .

[18]  C. H. Durney,et al.  An Investigation of the Use of Microwave Radiation for Pulmonary Diagnostics , 1976, IEEE Transactions on Biomedical Engineering.

[19]  B. W. Armstrong Clinical pulmonary function testing. , 1959, Annals of internal medicine.

[20]  M. Visscher,et al.  The physiology and pharmacology of lung edema. , 1956, Pharmacological reviews.