Identification of genes targeted by the androgen and PKA signaling pathways in prostate cancer cells

[1]  G. Wang,et al.  Amino‐terminus domain of the androgen receptor as a molecular target to prevent the hormonal progression of prostate cancer , 2006, Journal of cellular biochemistry.

[2]  P. Chumakov,et al.  Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP , 2005, Oncogene.

[3]  P. Murray,et al.  Microarray analysis of bicalutamide action on telomerase activity, p53 pathway and viability of prostate carcinoma cell lines , 2005, The Journal of pharmacy and pharmacology.

[4]  A. Jemal,et al.  Cancer Statistics, 2005 , 2005, CA: a cancer journal for clinicians.

[5]  D. Tindall,et al.  Mechanisms of androgen-refractory prostate cancer. , 2004, The New England journal of medicine.

[6]  A. Strasser,et al.  Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands. , 2004, The Biochemical journal.

[7]  D. Gerhold,et al.  Identification of Genetic Pathways Activated by the Androgen Receptor during the Induction of Proliferation in the Ventral Prostate Gland* , 2004, Journal of Biological Chemistry.

[8]  E. Latulippe,et al.  Gene expression analysis of human prostate carcinoma during hormonal therapy identifies androgen-responsive genes and mechanisms of therapy resistance. , 2004, The American journal of pathology.

[9]  R. Bornstein,et al.  A novel E2 box-GATA element modulates Cdc6 transcription during human cells polyploidization. , 2004, Nucleic acids research.

[10]  E. Aandahl,et al.  Localized effects of cAMP mediated by distinct routes of protein kinase A. , 2004, Physiological reviews.

[11]  C. Korch,et al.  Molecular characterization of human prostate carcinoma cell lines , 2003, The Prostate.

[12]  R. Aebersold,et al.  Androgen receptor represses the neuroendocrine transdifferentiation process in prostate cancer cells. , 2003, Molecular endocrinology.

[13]  S. Loening,et al.  mRNA expression of the five membrane‐type matrix metalloproteinases MT1–MT5 in human prostatic cell lines and their down‐regulation in human malignant prostatic tissue , 2003, The Prostate.

[14]  G. Siracusa,et al.  Dual effect of pituitary adenylate cyclase activating polypeptide on prostate tumor LNCaP cells: short- and long-term exposure affect proliferation and neuroendocrine differentiation. , 2003, Endocrinology.

[15]  Wei Zhang,et al.  Androgen-induced expression of endoplasmic reticulum (ER) stress response genes in prostate cancer cells , 2002, Oncogene.

[16]  Biaoyang Lin,et al.  The program of androgen-responsive genes in neoplastic prostate epithelium , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[17]  R. Chakrabarti,et al.  Down-regulation of Cdc6, a Cell Cycle Regulatory Gene, in Prostate Cancer* , 2002, The Journal of Biological Chemistry.

[18]  Robert Tibshirani,et al.  Transcriptional programs activated by exposure of human prostate cancer cells to androgen , 2002, Genome Biology.

[19]  A. Baniahmad,et al.  The amino terminus of the human AR is target for corepressor action and antihormone agonism. , 2002, Molecular endocrinology.

[20]  C. Huggins,et al.  Studies on prostatic cancer. I. The effect of castration, of estrogen and of androgen injection on serum phosphatases in metastatic carcinoma of the prostate. 1941. , 2002, The Journal of urology.

[21]  J. L. Shenk,et al.  p53 Represses Androgen-induced Transactivation of Prostate-specific Antigen by Disrupting hAR Amino- to Carboxyl-terminal Interaction* , 2001, The Journal of Biological Chemistry.

[22]  S. Hanash,et al.  Identification of androgen‐regulated genes in the prostate cancer cell line LNCaP by serial analysis of gene expression and proteomic analysis , 2001, Proteomics.

[23]  A. Levine,et al.  Wrch-1, a novel member of the Rho gene family that is regulated by Wnt-1. , 2001, Genes & development.

[24]  J. Moul,et al.  Quantitative expression profile of androgen‐regulated genes in prostate cancer cells and identification of prostate‐specific genes , 2001, International journal of cancer.

[25]  H. Schatten,et al.  Immunolocalization of NuMA and phosphorylated proteins during the cell cycle in human breast and prostate cancer cells as analyzed by immunofluorescence and postembedding immunoelectron microscopy , 2001, Histochemistry and Cell Biology.

[26]  R. Tibshirani,et al.  Significance analysis of microarrays applied to the ionizing radiation response , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[27]  C. Zeng NuMA: A nuclear protein involved in mitotic centrosome function , 2000, Microscopy research and technique.

[28]  E. Bissonette,et al.  Activated 3′,5′-Cyclic AMP-dependent Protein Kinase Is Sufficient to Induce Neuroendocrine-like Differentiation of the LNCaP Prostate Tumor Cell Line* , 2000, The Journal of Biological Chemistry.

[29]  E. Appella,et al.  p53 Regulates the Expression of the Tumor Suppressor Gene Maspin* , 2000, The Journal of Biological Chemistry.

[30]  G. Prins,et al.  Molecular biology of the androgen receptor. , 2000, Mayo Clinic proceedings.

[31]  R. Stroud,et al.  Signal sequence recognition and protein targeting. , 1999, Current opinion in structural biology.

[32]  N. Bruchovsky,et al.  Prostate cancer: molecular biology of early progression to androgen independence. , 1999, Endocrine-related cancer.

[33]  C. Cordon-Cardo,et al.  Prostate cancer cell cycle regulators: response to androgen withdrawal and development of androgen independence. , 1999, Journal of the National Cancer Institute.

[34]  S. Schwartz,et al.  A new human prostate carcinoma cell line, 22Rv1 , 1999, In Vitro Cellular & Developmental Biology - Animal.

[35]  M. Sadar Androgen-independent Induction of Prostate-specific Antigen Gene Expression via Cross-talk between the Androgen Receptor and Protein Kinase A Signal Transduction Pathways* , 1999, The Journal of Biological Chemistry.

[36]  W. Rosner,et al.  Sex hormone-binding globulin receptor signal transduction proceeds via a G protein , 1999, Steroids.

[37]  Leonard Buckbinder,et al.  PA26, a novel target of the p53 tumor suppressor and member of the GADD family of DNA damage and growth arrest inducible genes , 1999, Oncogene.

[38]  J. Nevins,et al.  Cdc6 is regulated by E2F and is essential for DNA replication in mammalian cells. , 1998, Proceedings of the National Academy of Sciences of the United States of America.

[39]  J. Habener,et al.  Cyclic AMP signaling and gene regulation. , 1998, Annual review of nutrition.

[40]  H. Klocker,et al.  Synergistic activation of androgen receptor by androgen and luteinizing hormone‐releasing hormone in prostatic carcinoma cells , 1997, The Prostate.

[41]  R. Sager,et al.  Expression of maspin in prostate cells is regulated by a positive ets element and a negative hormonal responsive element site recognized by androgen receptor. , 1997, Proceedings of the National Academy of Sciences of the United States of America.

[42]  L. Nazareth,et al.  Activation of the Human Androgen Receptor through a Protein Kinase A Signaling Pathway* , 1996, The Journal of Biological Chemistry.

[43]  J. D. Miller,et al.  Prostate-specific Antigen Expression Is Regulated by an Upstream Enhancer (*) , 1996, The Journal of Biological Chemistry.

[44]  J. Trapman,et al.  Two Androgen Response Regions Cooperate in Steroid Hormone Regulated Activity of the Prostate-specific Antigen Promoter (*) , 1996, The Journal of Biological Chemistry.

[45]  F. S. French,et al.  Specificity of ligand-dependent androgen receptor stabilization: receptor domain interactions influence ligand dissociation and receptor stability. , 1995, Molecular endocrinology.

[46]  G. Prins,et al.  Regulation of proliferation and production of prostate-specific antigen in androgen-sensitive prostatic cancer cells, LNCaP, by dihydrotestosterone. , 1995, Endocrinology.

[47]  Y. Bang,et al.  Terminal neuroendocrine differentiation of human prostate carcinoma cells in response to increased intracellular cyclic AMP. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[48]  W. Rayford,et al.  Calcitonin stimulates growth of human prostate cancer cells through receptor-mediated increase in cyclic adenosine 3',5'-monophosphates and cytoplasmic Ca2+ transients. , 1994, Endocrinology.

[49]  M. Parker,et al.  A consensus DNA-binding site for the androgen receptor. , 1992, Molecular endocrinology.

[50]  D. Tindall,et al.  Tissue-specific and hormonal regulation of human prostate-specific glandular kallikrein. , 1992, Biochemistry.

[51]  P. Riegman,et al.  The promoter of the prostate-specific antigen gene contains a functional androgen responsive element. , 1991, Molecular endocrinology.

[52]  A. Smith,et al.  Molecular cloning of a rat testis form of the inhibitor protein of cAMP-dependent protein kinase. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[53]  J. Goldstein,et al.  Regulation of the mevalonate pathway , 1990, Nature.