Active immunization with IL‐1 displayed on virus‐like particles protects from autoimmune arthritis
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G. Jennings | M. Bachmann | M. Beck | G. Spohn | P. Grest | Iris Keller
[1] T. Kündig,et al. A Virus-Like Particle-Based Vaccine Selectively Targeting Soluble TNF-α Protects from Arthritis without Inducing Reactivation of Latent Tuberculosis , 2007, The Journal of Immunology.
[2] H. Volk,et al. A vaccine for hypertension based on virus-like particles: preclinical efficacy and phase I safety and immunogenicity , 2007, Journal of hypertension.
[3] G. Jennings,et al. Vaccination against IL‐17 suppresses autoimmune arthritis and encephalomyelitis , 2006, European journal of immunology.
[4] J. Thurman,et al. Alternative Complement Pathway Activation Is Essential for Inflammation and Joint Destruction in the Passive Transfer Model of Collagen-Induced Arthritis1 , 2006, The Journal of Immunology.
[5] Kutty Selva Nandakumar,et al. Arthritis induced with cartilage‐specific antibodiesis IL‐4‐dependent , 2006, European journal of immunology.
[6] G. Burmester,et al. Safety of extended treatment with anakinra in patients with rheumatoid arthritis , 2006, Annals of the rheumatic diseases.
[7] K. Schwarz,et al. Protection against Osteoporosis by Active Immunization with TRANCE/RANKL Displayed on Virus-Like Particles , 2005, The Journal of Immunology.
[8] Kutty Selva Nandakumar,et al. Efficient promotion of collagen antibody induced arthritis (CAIA) using four monoclonal antibodies specific for the major epitopes recognized in both collagen induced arthritis and rheumatoid arthritis. , 2005, Journal of immunological methods.
[9] M. Lathrop,et al. Variation in IL-1beta gene expression is a major determinant of genetic differences in arthritis aggressivity in mice. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[10] J. Zagury,et al. Improvement of collagen-induced arthritis by active immunization against murine IL-1beta peptides designed by molecular modelling. , 2005, Vaccine.
[11] M. Broder,et al. Granulomatous infections due to tumor necrosis factor blockade: correction. , 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[12] Kutty Selva Nandakumar,et al. Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells , 2004, Arthritis research & therapy.
[13] R S Wallis,et al. Granulomatous infectious diseases associated with tumor necrosis factor antagonists. , 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[14] Kutty Selva Nandakumar,et al. Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes. , 2003, The American journal of pathology.
[15] J. Dayer. The pivotal role of interleukin-1 in the clinical manifestations of rheumatoid arthritis. , 2003, Rheumatology.
[16] G. Burmester,et al. Anakinra, a recombinant human interleukin-1 receptor antagonist (r-metHuIL-1ra), in patients with rheumatoid arthritis: A large, international, multicenter, placebo-controlled trial. , 2003, Arthritis and rheumatism.
[17] M. Braun,et al. Listeria monocytogenes infection as a complication of treatment with tumor necrosis factor alpha-neutralizing agents. , 2003, Arthritis and rheumatism.
[18] G. Lipowsky,et al. Regulation of IgG antibody responses by epitope density and CD21‐mediated costimulation , 2002, European journal of immunology.
[19] M. Braun,et al. Life-threatening histoplasmosis complicating immunotherapy with tumor necrosis factor alpha antagonists infliximab and etanercept. , 2002, Arthritis and rheumatism.
[20] S. Abramson,et al. Blocking the effects of IL-1 in rheumatoid arthritis protects bone and cartilage. , 2002, Rheumatology.
[21] W. Arend. The balance between IL-1 and IL-1Ra in disease. , 2002, Cytokine & growth factor reviews.
[22] T. Kagari,et al. The Importance of IL-1β and TNF-α, and the Noninvolvement of IL-6, in the Development of Monoclonal Antibody-Induced Arthritis , 2002, The Journal of Immunology.
[23] C. Benoist,et al. Critical Roles for Interleukin 1 and Tumor Necrosis Factor α in Antibody-induced Arthritis , 2002, The Journal of experimental medicine.
[24] K. Bendtzen,et al. Autoantibodies against interleukin 1α in rheumatoid arthritis: association with long term radiographic outcome , 2002, Annals of the rheumatic diseases.
[25] D. Hirsh,et al. The Epistatic Interrelationships of IL-1, IL-1 Receptor Antagonist, and the Type I IL-1 Receptor1 , 2002, The Journal of Immunology.
[26] Ralph Weissleder,et al. Arthritis critically dependent on innate immune system players. , 2002, Immunity.
[27] G. Panayi,et al. Cytokine pathways and joint inflammation in rheumatoid arthritis. , 2001, The New England journal of medicine.
[28] T. van der Poll,et al. Interleukin-1 signaling is essential for host defense during murine pulmonary tuberculosis. , 2000, The Journal of infectious diseases.
[29] Y. Iwakura,et al. Protective Role of Interleukin-1 in Mycobacterial Infection in IL-1 α/β Double-Knockout Mice , 2000, Laboratory Investigation.
[30] I. Otterness,et al. Cytokine vaccination: neutralising IL-1α autoantibodies induced by immunisation with homologous IL-1α , 2000 .
[31] E. Hirsch,et al. Effects of Interleukin-1 Receptor Antagonist Overexpression on Infection by Listeria monocytogenes , 1999, Infection and Immunity.
[32] K. McIntyre,et al. Absence of IL-1 signaling and reduced inflammatory response in IL-1 type I receptor-deficient mice. , 1997, Journal of immunology.
[33] S. Paul,et al. Functions of interleukin 1 receptor antagonist in gene knockout and overproducing mice. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[34] C. Dinarello,et al. Biologic basis for interleukin-1 in disease. , 1996, Blood.
[35] T. Pincus,et al. Prognostic markers of activity and damage in rheumatoid arthritis: why clinical trials and inception cohort studies indicate more favourable outcomes than studies of patients with established disease. , 1995, British journal of rheumatology.
[36] J. Banchereau,et al. Balance of IL-1 receptor antagonist/IL-1 beta in rheumatoid synovium and its regulation by IL-4 and IL-10. , 1995, Journal of immunology.
[37] G. Firestein,et al. Synovial interleukin-1 receptor antagonist and interleukin-1 balance in rheumatoid arthritis. , 1994, Arthritis and rheumatism.
[38] M. Denis,et al. Interleukin-1 is involved in mouse resistance to Mycobacterium avium , 1994, Infection and immunity.
[39] R. Zinkernagel,et al. The influence of antigen organization on B cell responsiveness. , 1993, Science.
[40] J. Mier,et al. Pharmacokinetics, safety and immunomodulatory effects of human recombinant interleukin-1 receptor antagonist in healthy humans. , 1992, Cytokine.
[41] K. Bendtzen,et al. IgG Autoantibodies against Interleukin 1α in Sera of Normal Individuals , 1989 .
[42] C. Avnstorp,et al. Interleukin‐1 , 1987 .
[43] K. Nishioka,et al. Efficacy of daily compared to intermittent administration of IL-1Ra for protection against bone and cartilage destruction in collagen-challenged mice. , 2003, Clinical and experimental rheumatology.
[44] T. Kagari,et al. The importance of IL-1 beta and TNF-alpha, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis. , 2002, Journal of immunology.
[45] I. Otterness,et al. Cytokine vaccination: neutralising IL-1alpha autoantibodies induced by immunisation with homologous IL-1alpha. , 2000, Journal of immunological methods.
[46] Y. Iwakura,et al. Protective role of interleukin-1 in mycobacterial infection in IL-1 alpha/beta double-knockout mice. , 2000, Laboratory investigation; a journal of technical methods and pathology.
[47] T. Pincus. Long-term outcomes in rheumatoid arthritis. , 1995, British journal of rheumatology.
[48] K. Bendtzen,et al. IgG autoantibodies against interleukin 1 alpha in sera of normal individuals. , 1989, Scandinavian journal of immunology.