Mutant p53 gain of function: differential effects of different p53 mutants on resistance of cultured cells to chemotherapy
暂无分享,去创建一个
[1] J. Cleveland,et al. Activation of c-myc Gene Expression by Tumor-Derived p53 Mutants Requires a Discrete C-Terminal Domain , 1998, Molecular and Cellular Biology.
[2] V. Rotter,et al. Mutant p53 protein expression interferes with p53-independent apoptotic pathways , 1998, Oncogene.
[3] S. Deb,et al. `Gain of function' phenotype of tumor-derived mutant p53 requires the oligomerization/nonsequence-specific nucleic acid-binding domain , 1998, Oncogene.
[4] K. Aldape,et al. An oncogenic form of p53 confers a dominant, gain-of-function phenotype that disrupts spindle checkpoint control. , 1998, Proceedings of the National Academy of Sciences of the United States of America.
[5] G. Prendergast,et al. The polyproline region of p53 is required to activate apoptosis but not growth arrest , 1997, Oncogene.
[6] A. Levine. p53, the Cellular Gatekeeper for Growth and Division , 1997, Cell.
[7] M. Oren,et al. p53; from inductive signal to cellular effect. , 1997, Current opinion in genetics & development.
[8] Peter A. Jones,et al. p53 and treatment of bladder cancer , 1997, Nature.
[9] G. Thomas,et al. P53 gene alterations in human tumors: perspectives for cancer control. , 1997, Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer.
[10] P. Chumakov,et al. Distinct effects of various p53 mutants on differentiation and viability of human K562 leukemia cells. , 1997, Oncology research.
[11] A. Levine,et al. Identification of a novel p53 functional domain that is necessary for efficient growth suppression. , 1996, Proceedings of the National Academy of Sciences of the United States of America.
[12] S. Deb,et al. Transcriptional activation of the human epidermal growth factor receptor promoter by human p53 , 1996, Molecular and cellular biology.
[13] T. Aas,et al. Specific P53 mutations are associated with de novo resistance to doxorubicin in breast cancer patients , 1996, Nature Medicine.
[14] N. Bleehen,et al. Expression of apoptosis-regulatory genes in lung tumour cell lines: relationship to p53 expression and relevance to acquired drug resistance. , 1996, British Journal of Cancer.
[15] S. Lowe,et al. Cancer therapy and p53. , 1995, Current opinion in oncology.
[16] E. Dmitrovsky,et al. Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer. , 1995, Cancer research.
[17] J. Lotem,et al. A mutant p53 antagonizes the deregulated c-myc-mediated enhancement of apoptosis and decrease in leukemogenicity. , 1995, Proceedings of the National Academy of Sciences of the United States of America.
[18] L. Holmberg,et al. Complete sequencing of the p53 gene provides prognostic information in breast cancer patients, particularly in relation to adjuvant systemic therapy and radiotherapy , 1995, Nature Medicine.
[19] E. Shaulian,et al. Induction of apoptosis in HeLa cells by trans-activation-deficient p53. , 1995, Genes & development.
[20] E. Hovig,et al. TP53 mutations and breast cancer prognosis: Particularly poor survival rates for cases with mutations in the zinc‐binding domains , 1995, Genes, chromosomes & cancer.
[21] Z. Darżynkiewicz. Apoptosis in anititumor strategies: Modulation of cell cycle or differentiation , 1995, Journal of cellular biochemistry.
[22] T. Powles,et al. p53 protein overexpression and chemosensitivity in breast cancer , 1995, The Lancet.
[23] G. Ebers,et al. Ondansetron for intractable vertigo complicating acute brainstem disorders , 1995, The Lancet.
[24] J Milner,et al. Flexibility: the key to p53 function? , 1995, Trends in biochemical sciences.
[25] D. Fisher. Apoptosis in cancer therapy: Crossing the threshold , 1994, Cell.
[26] E. Newcomb,et al. p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression , 1993 .
[27] A. Fornace,et al. Induction of Cellular p53 Activity by DNA-Damaging Agents and Growth Arrest , 1993, Molecular and cellular biology.
[28] A. Levine,et al. Gain of function mutations in p53 , 1993, Nature Genetics.
[29] C. Purdie,et al. Thymocyte apoptosis induced by p53-dependent and independent pathways , 1993, Nature.
[30] Scott W. Lowe,et al. p53 is required for radiation-induced apoptosis in mouse thymocytes , 1993, Nature.
[31] M. Subler,et al. Modulation of cellular and viral promoters by mutant human p53 proteins found in tumor cells , 1992, Journal of virology.
[32] I. Pastan,et al. Modulation of activity of the promoter of the human MDR1 gene by Ras and p53. , 1992, Science.
[33] B. Vogelstein,et al. Participation of p53 protein in the cellular response to DNA damage. , 1991, Cancer research.
[34] O. Halevy,et al. p53 Mutations: Gains or losses? , 1991, Journal of cellular biochemistry.
[35] V. Rotter,et al. Reconstitution of p53 expression in a nonproducer Ab-MuLV-transformed cell line by transfection of a functional p53 gene , 1984, Cell.