Proof of concept for quantitative urine NMR metabolomics pipeline for large-scale epidemiology and genetics
暂无分享,去创建一个
Minna Männikkö | Michael Hill | Michael V Holmes | Qin Wang | Jaspal Kooner | Mika Ala-Korpela | Jouko Vepsäläinen | Marjo-Riitta Järvelin | George Davey Smith | Susan Ring | Tuulia Tynkkynen | Jussi Ekholm | Olga Anufrieva | Pauli Ohukainen | Sirkka Keinänen-Kiukaanniemi | Matthew Goodwin | John C Chambers | Johannes Kettunen
[1] Tom R. Gaunt,et al. Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis , 2017, Circulation.
[2] Jimmy D Bell,et al. Assessment of quantitative artificial neural network analysis in a metabolically dynamic ex vivo 31p NMR pig liver study , 1997, Magnetic resonance in medicine.
[3] Debbie A Lawlor,et al. Quantitative Serum Nuclear Magnetic Resonance Metabolomics in Large-Scale Epidemiology: A Primer on -Omic Technologies , 2017, American journal of epidemiology.
[4] Reino Laatikainen,et al. High-throughput serum NMR metabonomics for cost-effective holistic studies on systemic metabolism. , 2009, The Analyst.
[5] M. Pirinen,et al. Genome-wide study for circulating metabolites identifies 62 loci and reveals novel systemic effects of LPA , 2016, Nature Communications.
[6] G. Davey Smith,et al. Genetic Support for a Causal Role of Insulin Resistance on Circulating Branched-Chain Amino Acids and Inflammation , 2017, Diabetes Care.
[7] Alan M. Kwong,et al. A reference panel of 64,976 haplotypes for genotype imputation , 2015, Nature Genetics.
[8] Ian J. Brown,et al. Human metabolic phenotype diversity and its association with diet and blood pressure , 2008, Nature.
[9] S. Ebrahim,et al. 'Mendelian randomization': can genetic epidemiology contribute to understanding environmental determinants of disease? , 2003, International journal of epidemiology.
[10] Christian Gieger,et al. A genome-wide association study of metabolic traits in human urine , 2011, Nature Genetics.
[11] Reino Laatikainen,et al. Strategies for organic impurity quantification by 1H NMR spectroscopy: Constrained total-line-shape fitting , 2005 .
[12] Erin E. Carlson,et al. Targeted profiling: quantitative analysis of 1H NMR metabolomics data. , 2006, Analytical chemistry.
[13] Markus Perola,et al. Genome-wide association study identifies multiple loci influencing human serum metabolite levels , 2012, Nature Genetics.
[14] D. Corella,et al. Metabolomic pattern analysis after mediterranean diet intervention in a nondiabetic population: a 1- and 3-year follow-up in the PREDIMED study. , 2015, Journal of proteome research.
[15] Samuli Ripatti,et al. Metabolic Signatures of Adiposity in Young Adults: Mendelian Randomization Analysis and Effects of Weight Change , 2014, PLoS medicine.
[16] Cheng Zheng,et al. Identification and quantification of metabolites in 1H NMR spectra by Bayesian model selection , 2011, Bioinform..
[17] A. Smilde,et al. Of Monkeys and Men: A Metabolomic Analysis of Static and Dynamic Urinary Metabolic Phenotypes in Two Species , 2014, PloS one.
[18] P. Donnelly,et al. A new multipoint method for genome-wide association studies by imputation of genotypes , 2007, Nature Genetics.
[19] Brian J. Bennett,et al. Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease , 2011, Nature.
[20] Francesco Savorani,et al. Assessment of the Effect of High or Low Protein Diet on the Human Urine Metabolome as Measured by NMR , 2012, Nutrients.
[21] D. Jacobs,et al. Assessment of dietary exposure and effect in humans: The role of NMR. , 2016, Progress in nuclear magnetic resonance spectroscopy.
[22] S Mierisová,et al. MR spectroscopy quantitation: a review of frequency domain methods , 2001, NMR in biomedicine.
[23] Alun D. Hughes,et al. Metabolomic Profiling of Statin Use and Genetic Inhibition of HMG-CoA Reductase , 2016, Journal of the American College of Cardiology.
[24] Markus Perola,et al. Metabonomic, transcriptomic, and genomic variation of a population cohort , 2010, Molecular systems biology.
[25] M. Ala-Korpela. Objective Metabolomics Research. , 2018, Clinical chemistry.
[26] R. Sinha,et al. Comparing metabolite profiles of habitual diet in serum and urine. , 2016, The American journal of clinical nutrition.
[27] Terho Lehtimäki,et al. Branched-Chain and Aromatic Amino Acids Are Predictors of Insulin Resistance in Young Adults , 2013, Diabetes Care.
[28] Garcia-Perez. Urintest für Ernährung , 2017, DMW - Deutsche Medizinische Wochenschrift.
[29] Zerihun T. Dame,et al. The Human Urine Metabolome , 2013, PloS one.
[30] P. Elliott,et al. Urinary metabolic signatures of human adiposity , 2015, Science Translational Medicine.
[31] Tom R. Gaunt,et al. Metabolite profiling and cardiovascular event risk: a prospective study of 3 population-based cohorts. , 2015, Circulation.
[32] Rachel Gibson,et al. Objective assessment of dietary patterns by use of metabolic phenotyping: a randomised, controlled, crossover trial , 2017, The lancet. Diabetes & endocrinology.
[33] Aki Vehtari,et al. A novel Bayesian approach to quantify clinical variables and to determine their spectroscopic counterparts in 1H NMR metabonomic data , 2007, BMC Bioinformatics.
[34] T. Bezabeh,et al. Diagnostic Applications of Nuclear Magnetic Resonance–Based Urinary Metabolomics , 2017, Magnetic resonance insights.
[35] G. Davey Smith,et al. Metabolic profiling–multitude of technologies with great research potential, but (when) will translation emerge? , 2016, International journal of epidemiology.
[36] Pasi Soininen,et al. Quantitative serum nuclear magnetic resonance metabolomics in cardiovascular epidemiology and genetics. , 2015, Circulation. Cardiovascular genetics.
[37] Tuija Tammelin,et al. Metabolic Signatures of Insulin Resistance in 7,098 Young Adults , 2012, Diabetes.
[38] David S. Wishart,et al. Recommendations and Standardization of Biomarker Quantification Using NMR-Based Metabolomics with Particular Focus on Urinary Analysis , 2016, Journal of proteome research.
[39] V. Mootha,et al. Metabolite profiles and the risk of developing diabetes , 2011, Nature Medicine.
[40] M. J. Ornstrup,et al. Comprehensive Metabolomic Analysis in Blood, Urine, Fat, and Muscle in Men with Metabolic Syndrome: A Randomized, Placebo-Controlled Clinical Trial on the Effects of Resveratrol after Four Months’ Treatment , 2017, International journal of molecular sciences.
[41] D. Lawlor,et al. Metabolic signatures of birthweight in 18 288 adolescents and adults , 2016, International journal of epidemiology.
[42] Maria De Iorio,et al. Bayesian deconvolution and quantification of metabolites in complex 1D NMR spectra using BATMAN , 2014, Nature Protocols.
[43] D. Lawlor,et al. Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence , 2016, BMC Medicine.
[44] Peter Donnelly,et al. Human metabolic profiles are stably controlled by genetic and environmental variation , 2011, Molecular systems biology.
[45] Kimmo Kaski,et al. Detailed metabolic and genetic characterization reveals new associations for 30 known lipid loci. , 2012, Human molecular genetics.
[46] A. El-Aneed,et al. Mass spectrometric based approaches in urine metabolomics and biomarker discovery. , 2017, Mass spectrometry reviews.
[47] C. Franceschi,et al. High-Resolution Quantitative Metabolome Analysis of Urine by Automated Flow Injection NMR , 2013, Analytical chemistry.
[48] Christian Gieger,et al. Genome-Wide Association Study with Targeted and Non-targeted NMR Metabolomics Identifies 15 Novel Loci of Urinary Human Metabolic Individuality , 2015, PLoS genetics.