论文信息 - Iodo-cyclization of N-Homoallyl Thioamides Leading to 2,4-Diaryl-5,6-dihydro-4H-1,3-thiazines - 字舞流文

Iodo-cyclization of N-Homoallyl Thioamides Leading to 2,4-Diaryl-5,6-dihydro-4H-1,3-thiazines

Iodo-cyclization of N-homoallyl thioamides was carried out in the presence of Et3N to form 2,4-diaryl-5,6-dihydro-4H-1,3-thiazines in good to high yields. The reaction of thioamides bearing 1-napht...

F. Shibahara | T. Murai | Tsutomu Kimura | H. Niwa

[1] T. Murai,et al. Reaction and characterization of thioamide dianions derived from N-benzyl thioamides. , 2003, Journal of Organic Chemistry.

[2] L. Toupet,et al. The hetero Diels–Alder reaction featuring 2-phenyl-4-dimethylamino-1-thia-3-azabuta-1,3-diene as diene component: a clear example of a thermodynamically-controlled process , 2002 .

[3] M. Sakamoto,et al. Stereoselective Synthesis of 4H‐5,6‐Dihydro‐1,3‐thiazines by the Reaction of 3‐N‐Acylamino Alcohols with Lawesson’s Reagent , 2001 .

[4] P. Wipf,et al. Synthesis of oxazines and thiazines by cyclodehydration of hydroxy amides and thioamides , 1998 .

[5] A. Guingant,et al. 1H NMR evaluation of the enantiomeric purity of a series of heterocyclic β-dimethylamino esters and amides by using (S)-mandelic acid derivatives as chiral solvating agents , 1998 .

[6] Michinori Karikomi,et al. Stereoselective Synthesis of 4,5-Dihydro-1,3-thiazole and 4H-5,6-Dihydro-1,3-thiazine Derivatives , 1995 .

[7] P. Creeke,et al. Synthessi and elaboration of heterocycles via iodocyclisation of unsaturated thioureas , 1989 .