Hormonal regulation of hepatic gluconeogenesis and glycolysis.
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MODULATION OF THE PHOSPHORYLATION STATE OF KEY REGULATORY HEPATIC ENZyMES. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 759 Pyruvate Kinase . . . . . .. . . . . . . . . . .. . . . . . . . . . . . .. . . . . ..... . . .. . . . . . . . . . . .... . .. . . .. . . . . . . . .. . . . . . . ... 759 6-Phosphofructo-l-Kinase and Fructose-l ,6-Bisphosphatase . . . . . . . ... . . . .. . . . .. . . . . . . . . . 761 6-Phosphofructo-2-KinaselFructose-2 ,6-Bisphosphatase . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 762 POSSIBLE MlITOCHONDRIAL SITES OF HORMONE ACTION ....... . . 769 LONG-TERM HORMONAL CONTROL OF GLYCOLYTIC AND GLUCONEOGENIC ENZyMES . . . . . . . .. . . . . . . . . . . . .. . . . . . . . . .. . . . . . . . . . . ". . . . . . . . . 770 Pyruvate Kinase... . . . . . . ..... . . . . . . . . . . .... . . . .... . . . ..... . . . . . . . . ..... . . .... . . . . . . . . . . .. . . .. . . . . . 770 Glucokinase. " . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . , . . . . . . . . . 770 6-Phosphofructo-l-Kinase and Fructose 1 ,6-Bisphosphatase. . . . . . .. . . . . . . . . . . .. . . .. . . . . . 771 6-Phospho}'ructo-2-KinaselFructose-2 ,6-Bisphosphatase . . . . . . . . . . . . .. . . . . ... . . . . .. .. . . . . . . 77 1 Phosphoenolpyruvate Carboxykinase.. . . . . . . . . . . . .. . . . . . . . . . . . . . . . . . . . . .. . . . . . . ....... . . . . . . . . 772 INTEGRATED REGULATION OF HEPATIC GLYCOLYSIS, GLUCONEOGENESIS, AND GLYCOGEN METABOLISM . . . . . . . . . . . . . . . . . . 773
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