Lobular breast cancer: molecular basis, mouse and cellular models

[1]  A. Turnbull,et al.  Molecular changes in lobular breast cancers in response to endocrine therapy. , 2014, Cancer research.

[2]  Jeffrey E. Green,et al.  Transcriptional Roles of PARP1 in Cancer , 2014, Molecular Cancer Research.

[3]  Julian Peto,et al.  Genetic Predisposition to In Situ and Invasive Lobular Carcinoma of the Breast , 2014, PLoS genetics.

[4]  D. Dabbs,et al.  Invasive lobular carcinoma cell lines are characterized by unique estrogen-mediated gene expression patterns and altered tamoxifen response. , 2014, Cancer research.

[5]  M. Simpson,et al.  Germline CDH1 mutations in bilateral lobular carcinoma in situ , 2013, British Journal of Cancer.

[6]  R. Geffers,et al.  IPH‐926 lobular breast cancer cells are triple‐negative but their microarray profile uncovers a luminal subtype , 2013, Cancer science.

[7]  U. Lehmann,et al.  Is Upregulation of BCL2 a Determinant of Tumor Development Driven by Inactivation of CDH1/E-Cadherin? , 2013, PloS one.

[8]  M. Geng,et al.  Luminal Breast Cancer Cell Lines Overexpressing ZNF703 Are Resistant to Tamoxifen through Activation of Akt/mTOR Signaling , 2013, PloS one.

[9]  P. V. van Diest,et al.  Loss of p120-catenin induces metastatic progression of breast cancer by inducing anoikis resistance and augmenting growth factor receptor signaling. , 2013, Cancer research.

[10]  A. Sézeur,et al.  CDH1 germline mutations and the hereditary diffuse gastric and lobular breast cancer syndrome: a multicentre study , 2013, Journal of Medical Genetics.

[11]  James X. Sun,et al.  Relapsed Classic E-Cadherin (CDH1)–Mutated Invasive Lobular Breast Cancer Shows a High Frequency of HER2 (ERBB2) Gene Mutations , 2013, Clinical Cancer Research.

[12]  J. Foekens,et al.  Loss of E-cadherin is not a necessity for epithelial to mesenchymal transition in human breast cancer , 2013, Breast Cancer Research and Treatment.

[13]  T. Krech,et al.  Oncogenic PIK3CA mutations in lobular breast cancer progression , 2013, Genes, chromosomes & cancer.

[14]  J. Jonkers,et al.  A preclinical mouse model of invasive lobular breast cancer metastasis. , 2013, Cancer research.

[15]  C. Perou,et al.  The genomic landscape of breast cancer as a therapeutic roadmap. , 2013, Cancer discovery.

[16]  R. Geffers,et al.  IPH-926 lobular breast cancer cells harbor a p53 mutant with temperature-sensitive functional activity and allow for profiling of p53-responsive genes , 2012, Laboratory Investigation.

[17]  Ulrich Lehmann,et al.  Nuclear Kaiso Expression Is Associated with High Grade and Triple-Negative Invasive Breast Cancer , 2012, PloS one.

[18]  R. Geffers,et al.  ABCB1/MDR1 contributes to the anticancer drug-resistant phenotype of IPH-926 human lobular breast cancer cells. , 2012, Cancer letters.

[19]  P. Bult,et al.  p53 mutations in classic and pleomorphic invasive lobular carcinoma of the breast , 2012, Cellular Oncology.

[20]  K. Horwitz,et al.  Estrogen switches pure mucinous breast cancer to invasive lobular carcinoma with mucinous features , 2012, Breast Cancer Research and Treatment.

[21]  A. Vincent-Salomon,et al.  Modeling of response to endocrine therapy in a panel of human luminal breast cancer xenografts , 2012, Breast Cancer Research and Treatment.

[22]  Mark T. W. Ebbert,et al.  Tumor grafts derived from women with breast cancer authentically reflect tumor pathology, growth, metastasis and disease outcomes , 2011, Nature Medicine.

[23]  R. Kemler,et al.  Replacement of E-cadherin by N-cadherin in the mammary gland leads to fibrocystic changes and tumor formation , 2011, Breast Cancer Research.

[24]  Y. Eishi,et al.  Synergistic tumour suppressor activity of E-cadherin and p53 in a conditional mouse model for metastatic diffuse-type gastric cancer , 2011, Gut.

[25]  Valerie Speirs,et al.  Choosing the right cell line for breast cancer research , 2011, Breast Cancer Research.

[26]  P. V. van Diest,et al.  Cytosolic p120-catenin regulates growth of metastatic lobular carcinoma through Rock1-mediated anoikis resistance. , 2011, The Journal of clinical investigation.

[27]  W. Birchmeier,et al.  E‐cadherin is crucial for embryonic stem cell pluripotency and can replace OCT4 during somatic cell reprogramming , 2011, EMBO reports.

[28]  F. Millanta,et al.  Canine invasive lobular carcinoma of the mammary gland: morphological and immunohistochemical characterizations of three cases. , 2011, Journal of comparative pathology.

[29]  Y. Eishi,et al.  Loss of E‐cadherin in mouse gastric epithelial cells induces signet ring‐like cells, a possible precursor lesion of diffuse gastric cancer , 2011, Cancer science.

[30]  C. Sotiriou,et al.  ZNF703 gene amplification at 8p12 specifies luminal B breast cancer , 2011, EMBO molecular medicine.

[31]  J. Wesseling,et al.  Mammary-specific inactivation of E-cadherin and p53 impairs functional gland development and leads to pleomorphic invasive lobular carcinoma in mice , 2011, Disease Models & Mechanisms.

[32]  V. Zappulli,et al.  Classification and Grading of Canine Mammary Tumors , 2011, Veterinary pathology.

[33]  A. Ashworth,et al.  FGFR1 amplification drives endocrine therapy resistance and is a therapeutic target in breast cancer. , 2010, Cancer research.

[34]  B. Kreike,et al.  The molecular underpinning of lobular histological growth pattern: a genome‐wide transcriptomic analysis of invasive lobular carcinomas and grade‐ and molecular subtype‐matched invasive ductal carcinomas of no special type , 2010, The Journal of pathology.

[35]  J. Foekens,et al.  Four human breast cancer cell lines with biallelic inactivating α-catenin gene mutations , 2010, Breast Cancer Research and Treatment.

[36]  Hans Clevers,et al.  Distinct gene mutation profiles among luminal-type and basal-type breast cancer cell lines , 2010, Breast Cancer Research and Treatment.

[37]  L. Wiesmüller,et al.  DNA double-strand break repair activities in mammary epithelial cells--influence of endogenous p53 variants. , 2009, Carcinogenesis.

[38]  D. Steinemann,et al.  Comprehensive genetic and functional characterization of IPH‐926: a novel CDH1‐null tumour cell line from human lobular breast cancer , 2009, The Journal of pathology.

[39]  P. Guilford,et al.  E-cadherin deficiency initiates gastric signet-ring cell carcinoma in mice and man. , 2009, Cancer research.

[40]  J. Xuan,et al.  ERRgamma mediates tamoxifen resistance in novel models of invasive lobular breast cancer. , 2008, Cancer research.

[41]  F. Bertucci,et al.  Lobular and ductal carcinomas of the breast have distinct genomic and expression profiles , 2008, Oncogene.

[42]  A. Ashworth,et al.  Molecular profiling pleomorphic lobular carcinomas of the breast: evidence for a common molecular genetic pathway with classic lobular carcinomas , 2008, The Journal of pathology.

[43]  C. Gottardi,et al.  Molecular components of the adherens junction. , 2008, Biochimica et biophysica acta.

[44]  I. Ellis,et al.  Invasive lobular carcinoma of the breast: response to hormonal therapy and outcomes. , 2008, European journal of cancer.

[45]  A. Vincent-Salomon,et al.  A New Model of Patient Tumor-Derived Breast Cancer Xenografts for Preclinical Assays , 2007, Clinical Cancer Research.

[46]  J. Jonkers,et al.  Modeling Metastatic Breast Cancer in Mice , 2007, Journal of Mammary Gland Biology and Neoplasia.

[47]  Wen-Lin Kuo,et al.  A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes. , 2006, Cancer cell.

[48]  Alan Mackay,et al.  FGFR1 Emerges as a Potential Therapeutic Target for Lobular Breast Carcinomas , 2006, Clinical Cancer Research.

[49]  Jos Jonkers,et al.  Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis. , 2006, Cancer cell.

[50]  P. Chérel,et al.  Response to neoadjuvant chemotherapy in lobular and ductal breast carcinomas: a retrospective study on 860 patients from one institution. , 2006, Annals of oncology : official journal of the European Society for Medical Oncology.

[51]  L. R. Hill,et al.  Hyperplastic and Neoplastic Lesions of the Mammary Gland in Macaques , 2006, Veterinary pathology.

[52]  L. Dorssers,et al.  Functional Screen for Genes Responsible for Tamoxifen Resistance in Human Breast Cancer Cells , 2006, Molecular Cancer Research.

[53]  J. Martín-Pérez,et al.  Cytoplasmic localization of p120ctn and E-cadherin loss characterize lobular breast carcinoma from preinvasive to metastatic lesions , 2004, Oncogene.

[54]  H. Pasolli,et al.  Conditional targeting of E-cadherin in skin: insights into hyperproliferative and degenerative responses. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[55]  R. Cardiff,et al.  The Comparative Pathology of Human and Mouse Mammary Glands , 2004, Journal of Mammary Gland Biology and Neoplasia.

[56]  Jane Fridlyand,et al.  Differentiation of lobular versus ductal breast carcinomas by expression microarray analysis. , 2003, Cancer research.

[57]  R. Kemler,et al.  E-cadherin is a survival factor for the lactating mouse mammary gland , 2002, Mechanisms of Development.

[58]  R. Roylance,et al.  Multiple ways of silencing E‐cadherin gene expression in lobular carcinoma of the breast , 2001, International journal of cancer.

[59]  Albert B. Reynolds,et al.  The Catenin p120ctnInteracts with Kaiso, a Novel BTB/POZ Domain Zinc Finger Transcription Factor , 1999, Molecular and Cellular Biology.

[60]  M. Westerfield,et al.  Characterization of paired tumor and non‐tumor cell lines established from patients with breast cancer , 1998, International journal of cancer.

[61]  Anthony E. Reeve,et al.  E-cadherin germline mutations in familial gastric cancer , 1998, Nature.

[62]  M. J. van de Vijver,et al.  © 1997 Cancer Research Campaign , 2022 .

[63]  D. Olsen,et al.  Brain metastasis model in athymic nude mice using a novel MUC1‐secreting human breast‐cancer cell line, MA11 , 1996, International journal of cancer.

[64]  M. Vijver,et al.  E‐cadherin is a tumour/invasion suppressor gene mutated in human lobular breast cancers. , 1995, The EMBO journal.

[65]  D. Riethmacher,et al.  A targeted mutation in the mouse E-cadherin gene results in defective preimplantation development. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[66]  W. Birchmeier,et al.  Differential loss of E-cadherin expression in infiltrating ductal and lobular breast carcinomas. , 1993, The American journal of pathology.

[67]  K. Rajewsky,et al.  Independent control of immunoglobulin switch recombination at individual switch regions evidenced through Cre-loxP-mediated gene targeting , 1993, Cell.

[68]  B. Weber,et al.  Differential isolation of normal luminal mammary epithelial cells and breast cancer cells from primary and metastatic sites using selective media. , 1993, Cancer research.

[69]  F. Jacob,et al.  Cell-cell interactions in early embryogenesis: A molecular approach to the role of calcium , 1981, Cell.

[70]  L. Engel,et al.  Human breast carcinoma cells in continuous culture: a review. , 1978, Cancer research.

[71]  M. Olivé,et al.  Breast tumor cell lines from pleural effusions. , 1974, Journal of the National Cancer Institute.

[72]  F. W. Foote,et al.  Classics in oncology: Lobular carcinoma in situ: A rare form of mammary cancer , 1982 .

[73]  R. A. Willis.  The Pathology of Tumours , 1917, Nature.