Sensitive, reliable and easy-performed laboratory monitoring of eculizumab therapy in atypical hemolytic uremic syndrome.
暂无分享,去创建一个
J. Wetzels | E. Volokhina | L. P. Van den Heuvel | T. Mollnes | T. V. D. van der Velden | N. C. van de Kar | G. Bergseth | D. Westra | T. van der Velden
[1] A. Blom,et al. Antibodies reactive to cleaved sites in complement proteins enable highly specific measurement of soluble markers of complement activation. , 2015, Molecular immunology.
[2] J. Andersen,et al. Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn. , 2015, Immunobiology.
[3] R. Porcher,et al. Assessing complement blockade in patients with paroxysmal nocturnal hemoglobinuria receiving eculizumab. , 2015, Blood.
[4] G. Ardissino,et al. Discontinuation of eculizumab maintenance treatment for atypical hemolytic uremic syndrome: a report of 10 cases. , 2014, American journal of kidney diseases : the official journal of the National Kidney Foundation.
[5] Francesco Tedesco,et al. Dynamics of complement activation in aHUS and how to monitor eculizumab therapy. , 2014, Blood.
[6] G. Ardissino,et al. Complement functional tests for monitoring eculizumab treatment in patients with atypical hemolytic uremic syndrome , 2014, Journal of thrombosis and haemostasis : JTH.
[7] J. Pu,et al. Successful discontinuation of eculizumab therapy in a patient with aHUS , 2014, Annals of Hematology.
[8] A. M. Shaw,et al. Electroluminescent TCC, C3dg and fB/Bb epitope assays for profiling complement cascade activation in vitro using an activated complement serum calibration standard. , 2014, Journal of immunological methods.
[9] D. Kavanagh,et al. Complement therapy in atypical haemolytic uraemic syndrome (aHUS) , 2013, Molecular immunology.
[10] P. Hillmen,et al. Thrombosis in paroxysmal nocturnal hemoglobinuria. , 2013, Blood.
[11] G. Remuzzi,et al. Terminal complement inhibitor eculizumab in atypical hemolytic-uremic syndrome. , 2013, The New England journal of medicine.
[12] S. Cataland,et al. Relapse of aHUS after discontinuation of therapy with eculizumab in a patient with aHUS and factor H mutation , 2013, Annals of Hematology.
[13] G. Rijkers,et al. Meningococcal Sepsis Complicating Eculizumab Treatment Despite Prior Vaccination , 2013, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.
[14] V. Frémeaux-Bacchi,et al. Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies , 2012, Nature Reviews Nephrology.
[15] E. Volokhina,et al. Novel C3 mutation p.Lys65Gln in aHUS affects complement factor H binding , 2012, Pediatric Nephrology.
[16] C. Sautès-Fridman,et al. A prevalent C3 mutation in aHUS patients causes a direct C3 convertase gain of function. , 2012, Blood.
[17] J. Wetzels,et al. A new era in the diagnosis and treatment of atypical haemolytic uraemic syndrome. , 2012, The Netherlands journal of medicine.
[18] M. Harboe,et al. Advances in assay of complement function and activation. , 2011, Advanced drug delivery reviews.
[19] L. Monnens,et al. Insufficient protection by Neisseria meningitidis vaccination alone during eculizumab therapy , 2011, Pediatric Nephrology.
[20] T. Mollnes,et al. Recurrent meningococcal sepsis in a presumptive immunocompetent host shown to be complement C5 deficient—a case report , 2011, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[21] A. Waters,et al. aHUS caused by complement dysregulation: new therapies on the horizon , 2010, Pediatric Nephrology.
[22] Giuseppe Remuzzi,et al. Atypical hemolytic-uremic syndrome. , 2009, The New England journal of medicine.
[23] T. Jokiranta,et al. Mutations of Factor H Impair Regulation of Surface-bound C3b by Three Mechanisms in Atypical Hemolytic Uremic Syndrome* , 2009, The Journal of Biological Chemistry.
[24] W. Fridman,et al. Mutations in complement C3 predispose to development of atypical hemolytic uremic syndrome. , 2008, Blood.
[25] A. Salar,et al. An Observational Study of Anaemia Management in Patients with NHL Receiving CHOP-14 or -21 (With or Without Rituximab) , 2008 .
[26] P. Zipfel,et al. Factor H dysfunction in patients with atypical hemolytic uremic syndrome contributes to complement deposition on platelets and their activation. , 2008, Blood.
[27] P. Zipfel,et al. Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency. , 2008, Blood.
[28] R. Brodsky,et al. Discovery and development of the complement inhibitor eculizumab for the treatment of paroxysmal nocturnal hemoglobinuria , 2007, Nature Biotechnology.
[29] B. Paul Morgan,et al. Gain-of-function mutations in complement factor B are associated with atypical hemolytic uremic syndrome , 2007, Proceedings of the National Academy of Sciences.
[30] G. Remuzzi,et al. Genetics of HUS: the impact of MCP, CFH, and IF mutations on clinical presentation, response to treatment, and outcome. , 2006, Blood.
[31] J. Goodship,et al. Mutations in complement factor I predispose to development of atypical hemolytic uremic syndrome. , 2005, Journal of the American Society of Nephrology : JASN.
[32] A. Buil,et al. Predisposition to atypical hemolytic uremic syndrome involves the concurrence of different susceptibility alleles in the regulators of complement activation gene cluster in 1q32. , 2005, Human molecular genetics.
[33] W. Fridman,et al. Complement factor I: a susceptibility gene for atypical haemolytic uraemic syndrome , 2004, Journal of Medical Genetics.
[34] G. Remuzzi,et al. Familial haemolytic uraemic syndrome and an MCP mutation , 2003, The Lancet.
[35] J. Goodship,et al. Mutations in human complement regulator, membrane cofactor protein (CD46), predispose to development of familial hemolytic uremic syndrome , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[36] M. Walport. Complement. First of two parts. , 2001, The New England journal of medicine.
[37] Wiklund Ra,et al. First of two parts , 1997 .
[38] Henry P. Treffers,et al. Complement , 1966, The Yale Journal of Biology and Medicine.
[39] J. Stockman. Thrombomodulin Mutations in Atypical Hemolytic–Uremic Syndrome , 2011 .