Hes1 immortalizes committed progenitors and plays a role in blast crisis transition in chronic myelogenous leukemia.
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S. Ogawa | T. Kitamura | M. Kurokawa | S. Chiba | K. Kumano | M. Sakata-Yanagimoto | H. Harada | T. Uchida | F. Nakahara | J. Kitaura | Y. Komeno | Y. Harada | N. Kato | K. Haraguchi | Tomoyuki Uchida
[1] M. Seto,et al. Gain‐of‐function mutations and copy number increases of Notch2 in diffuse large B‐cell lymphoma , 2009, Cancer science.
[2] Daniel G Tenen,et al. Dysregulation of the C/EBPalpha differentiation pathway in human cancer. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] James M. Roberts,et al. Control of the Reversibility of Cellular Quiescence by the Transcriptional Repressor HES1 , 2008, Science.
[4] S. Ogawa,et al. Coordinated regulation of transcription factors through Notch2 is an important mediator of mast cell fate , 2008, Proceedings of the National Academy of Sciences.
[5] Heidi Dvinge,et al. Modeling of C/EBPalpha mutant acute myeloid leukemia reveals a common expression signature of committed myeloid leukemia-initiating cells. , 2008, Cancer cell.
[6] K. McCue,et al. Sonic Hedgehog regulates Hes1 through a novel mechanism that is independent of canonical Notch pathway signalling , 2008, Oncogene.
[7] T. Golub,et al. Transformation from committed progenitor to leukaemia stem cell initiated by MLL–AF9 , 2006, Nature.
[8] L. Fu,et al. NOTCH1 mutations are rare in acute myeloid leukemia , 2006, Leukemia & lymphoma.
[9] Y. Hayashi,et al. Mutations of the Notch1 gene in T-cell acute lymphoblastic leukemia: analysis in adults and children , 2005, Leukemia.
[10] M. Fey,et al. The Notch pathway in ovarian carcinomas and adenomas , 2005, British Journal of Cancer.
[11] K. Akashi,et al. Identification of eosinophil lineage–committed progenitors in the murine bone marrow , 2005, The Journal of experimental medicine.
[12] Hideaki Nakajima,et al. Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis. , 2005, The Journal of clinical investigation.
[13] T. Lister,et al. Mutation of CEBPA in familial acute myeloid leukemia. , 2004, The New England journal of medicine.
[14] Pu Zhang,et al. Enhancement of hematopoietic stem cell repopulating capacity and self-renewal in the absence of the transcription factor C/EBP alpha. , 2004, Immunity.
[15] K. Akashi,et al. MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors. , 2004, Cancer cell.
[16] Arie Perry,et al. Notch1 and Notch2 Have Opposite Effects on Embryonal Brain Tumor Growth , 2004, Cancer Research.
[17] Joel I. Pritchard,et al. The SmoA1 Mouse Model Reveals That Notch Signaling Is Critical for the Growth and Survival of Sonic Hedgehog-Induced Medulloblastomas , 2004, Cancer Research.
[18] Andrew P. Weng,et al. Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia , 2004, Science.
[19] Laurie E Ailles,et al. Granulocyte-macrophage progenitors as candidate leukemic stem cells in blast-crisis CML. , 2004, The New England journal of medicine.
[20] M. Nakafuku,et al. Hes binding to STAT3 mediates crosstalk between Notch and JAK–STAT signalling , 2004, Nature Cell Biology.
[21] C. Nerlov. C/EBPα mutations in acute myeloid leukaemias , 2004, Nature Reviews Cancer.
[22] Freddy Radtke,et al. Notch regulation of lymphocyte development and function , 2004, Nature Immunology.
[23] I. Weissman,et al. Similar MLL-associated leukemias arising from self-renewing stem cells and short-lived myeloid progenitors. , 2003, Genes & development.
[24] T. Kitamura,et al. Retrovirus-mediated gene transfer and expression cloning: powerful tools in functional genomics. , 2003, Experimental hematology.
[25] I. Weissman,et al. Expression of BCR/ABL and BCL-2 in myeloid progenitors leads to myeloid leukemias , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[26] R. Kageyama,et al. HES-1 preserves purified hematopoietic stem cells ex vivo and accumulates side population cells in vivo. , 2003, Blood.
[27] J. Aster,et al. Notch Signaling in Cancer , 2002, Cancer biology & therapy.
[28] W. El-Deiry. Transactivation of Repair Genes by BRCA1 , 2002, Cancer biology & therapy.
[29] C. Lavau,et al. Overexpression of the Notch target genes Hes in vivo induces lymphoid and myeloid alterations , 2002, Oncogene.
[30] J. Aster,et al. An Invitation to T and More Notch Signaling in Lymphopoiesis , 2002, Cell.
[31] Carl W. Miller,et al. Mutations in the gene encoding the transcription factor CCAAT/enhancer binding protein alpha in myelodysplastic syndromes and acute myeloid leukemias. , 2002, Blood.
[32] T. Yamagata,et al. Notch1 inhibits differentiation of hematopoietic cells by sustaining GATA-2 expression. , 2001, Blood.
[33] T. Kitamura,et al. Plat-E: an efficient and stable system for transient packaging of retroviruses , 2000, Gene Therapy.
[34] I. Weissman,et al. A clonogenic common myeloid progenitor that gives rise to all myeloid lineages , 2000, Nature.
[35] H. Nakauchi,et al. A Role for Pref-1 and HES-1 in Thymocyte Development , 2000, The Journal of Immunology.
[36] K. Tomita,et al. The bHLH gene Hes1 is essential for expansion of early T cell precursors. , 1999, Genes & development.
[37] H. Macdonald,et al. Deficient T cell fate specification in mice with an induced inactivation of Notch1. , 1999, Immunity.
[38] A. Israël,et al. Delta-1 Activation of Notch-1 Signaling Results inHES-1 Transactivation , 1998, Molecular and Cellular Biology.
[39] R. Kageyama,et al. Helix-loop-helix factors in growth and differentiation of the vertebrate nervous system. , 1997, Current opinion in genetics & development.
[40] F. Ferrara,et al. JURL-MK1 (c-kithigh/CD30−/CD40−) and JURL-MK2 (c-kitlow/CD30+/CD40+) cell lines: ‘two-sided’ model for investigating leukemic megakaryocytopoiesis , 1997, Leukemia.
[41] Christel Brou,et al. Signalling downstream of activated mammalian Notch , 1995, Nature.
[42] Y. Yazaki,et al. Expression of p210bcr/abl by metallothionein promoter induced T-cell leukemia in transgenic mice. , 1995, Blood.
[43] R. Sasaki,et al. Establishment of an erythroid cell line (JK‐1) that spontaneously differentiates to red cells , 1990, Cancer.
[44] David J. Anderson,et al. Two rat homologues of Drosophila achaete-scute specifically expressed in neuronal precursors , 1990, Nature.
[45] C. Lozzio,et al. Human chronic myelogenous leukemia cell-line with positive Philadelphia chromosome. , 1975, Blood.
[46] C. Nerlov. C/EBPalpha mutations in acute myeloid leukaemias. , 2004, Nature reviews. Cancer.
[47] M. Masu,et al. Conversion of biliary system to pancreatic tissue in Hes1-deficient mice , 2004, Nature Genetics.
[48] A. Gotoh,et al. Tyrosine phosphorylation and activation of focal adhesion kinase (p125FAK) by BCR-ABL oncoprotein. , 1995, Experimental hematology.
[49] I. Miyoshi,et al. Establishment of a Ph1 chromosome-positive cell line from chronic myelogenous leukemia in blast crisis. , 1983, International journal of cell cloning.
[50] I. Bernstein,et al. Hedgehog-Induced Medulloblastomas Critical for the Growth and Survival of Sonic The SmoA 1 Mouse Model Reveals That Notch Signaling Is Updated , 2022 .