论文信息 - p53: out of Africa - 字舞流文

p53: out of Africa

This Outlook examines Jennis et al.’s finding that a naturally occurring p53 polymorphism found in people of African decent impairs ferroptosis and p53-mediated tumor suppression.

[1] Michelle R. Campbell,et al. An African-specific polymorphism in the TP53 gene impairs p53 tumor suppressor function in a mouse model , 2016, Genes & development.

[2] R. Ahima,et al. The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction. , 2016, Cell reports.

[3] W. Gu,et al. Ferroptosis as a p53-mediated activity during tumour suppression , 2015, Nature.

[4] Karen H. Vousden,et al. Mutant p53 in Cancer: New Functions and Therapeutic Opportunities , 2014, Cancer cell.

[5] C. Coffill,et al. The role of mutant p53 in human cancer , 2011, The Journal of pathology.

[6] M. Murphy,et al. Polymorphisms in the p53 pathway , 2006, Oncogene.

[7] M. Hollstein,et al. Knock-in mice with a chimeric human/murine p53 gene develop normally and show wild-type p53 responses to DNA damaging agents: a new biomedical research tool , 2001, Oncogene.

[8] S. Friend,et al. Germline mutations of the p53 tumor-suppressor gene in children and young adults with second malignant neoplasms. , 1992, The New England journal of medicine.

[9] Jorge Zerón-Medina,et al. Single-nucleotide Polymorphisms in the p 53 Signaling Pathway , 2010 .

[10] Robins,et al. Single-Nucleotide Polymorphisms in the p 53 Pathway , 2006 .