In today’s changing world of medicine, it is of great importance to pay attention to surgical site infections (SSIs). Nowadays, much research is focused on the prevention of such infections, because they can cause unnecessary pain, fear and inconvenience for the patient. This can manifest as longer hospitalization, permanent disability or even death. By preventing SSIs, the morbidity, mortality and additional costs will be decreased. Additionally, the antibiotic resistance will be addressed. To prevent SSIs, special guidelines have been compiled and applied within hospitals in order to maintain patients’ safety. However, it is known that compliance with these guidelines could be improved. This study focuses on the prevention of SSIs. Here will be investigated if there is a possibility to develop an eHealth technology that supports the compliance with SSI guidelines by the operating theatre staff. The aim of this study is to determine the added values assigned to a supporting technology in the compliance with SSI guidelines, in order to develop requirements and persuasive features. These are required for further research in the development of an eHealth technology.