Skeletal muscle stiffness in static and dynamic contractions.

Series elastic stiffness of rat gastrocnemius medialis muscle was determined by means of sinusoidal movements (180 Hz, 0.25% of muscle length) for various contraction conditions. The effects of muscle length, activation level, velocity, prestretch, and temperature on the force-stiffness relationship were investigated. All force-stiffness curves were transformed to a linear force-alpha curve (Ettema and Huijing, 1993; Morgan, 1977) to distinguish mathematically two series elastic components; a force dependent and force independent compliance. For all isometric conditions a typical force-stiffness curve was found, where stiffness increased with force, and this increase levelled off at higher forces. Stiffness in dynamic shortening and lengthening contractions is related to force in a completely different way than in isometric condition. An increase in temperature caused a decrease in muscle stiffness for a given force, and the effects of muscle length, activation level, and prestretch were small. It was concluded that the series elastic component of skeletal-muscle-tendon complex is probably located in more than two morphologically identifiable elements. Furthermore, we concluded that using a single series elastic element in muscle modelling is not appropriate to describe muscle behaviour under all conditions that occur during in vivo activation.

[1]  A. Hill.  First and Last Experiments in Muscle Mechanics , 1970 .

[2]  M. Noble,et al.  Enhancement of mechanical performance by stretch during tetanic contractions of vertebrate skeletal muscle fibres. , 1978, The Journal of physiology.

[3]  Jack M. Winters,et al.  Multiple Muscle Systems , 1990, Springer New York.

[4]  David Morgan,et al.  Modeling of Lengthening Muscle: The Role of Inter-Sarcomere Dynamics , 1990 .

[5]  A. Huxley,et al.  Tension responses to sudden length change in stimulated frog muscle fibres near slack length , 1977, The Journal of physiology.

[6]  K W Ranatunga,et al.  Temperature‐dependence of shortening velocity and rate of isometric tension development in rat skeletal muscle , 1982, The Journal of physiology.

[7]  E. H. Harris,et al.  Stress-strain characteristics and tensile strength of unembalmed human tendon. , 1968, Journal of biomechanics.

[8]  Length-force characteristics of aponeurosis in passive muscle and during isometric and slow dynamic contractions of rat gastrocnemius muscle. , 1988, Acta morphologica Neerlando-Scandinavica.

[9]  D. Stephenson,et al.  Dissociation of force from myofibrillar MgATPase and stiffness at short sarcomere lengths in rat and toad skeletal muscle. , 1989, The Journal of physiology.

[10]  G A Cavagna,et al.  STORAGE AND UTILIZATION OF ELASTIC ENERGY IN SKELETAL MUSCLE , 1977, Exercise and sport sciences reviews.

[11]  D L Morgan,et al.  Variation of muscle stiffness with tension during tension transients and constant velocity shortening in the frog. , 1981, The Journal of physiology.

[12]  P. Huijing,et al.  Length-force characteristics of the aponeurosis in the passive and active muscle condition and in the isolated condition. , 1994, Journal of biomechanics.

[13]  T. Tsuchiya,et al.  Stiffness changes during enhancement and deficit of isometric force by slow length changes in frog skeletal muscle fibres. , 1988, The Journal of physiology.

[14]  K. Edman.  Mechanical deactivation induced by active shortening in isolated muscle fibres of the frog. , 1975, The Journal of physiology.

[15]  R. F. Ker,et al.  Mechanical properties of various mammalian tendons , 1986 .

[16]  P A Huijing,et al.  Frequency response to rat gastrocnemius medialis in small amplitude vibrations. , 1994, Journal of biomechanics.

[17]  P A Huijing,et al.  The potentiating effect of prestretch on the contractile performance of rat gastrocnemius medialis muscle during subsequent shortening and isometric contractions. , 1992, The Journal of experimental biology.

[18]  C B Frank,et al.  The effects of temperature on the viscoelastic properties of the rabbit medial collateral ligament. , 1990, Journal of biomechanical engineering.

[19]  K. Ranatunga,et al.  Temperature dependence of isometric contractions of cat fast and slow skeletal muscles. , 1984, The Journal of physiology.

[20]  D. Morgan.  Separation of active and passive components of short-range stiffness of muscle. , 1977, The American journal of physiology.

[21]  P. A. Huijing,et al.  Series Elastic Properties of Rat Skeletal Muscle: Distinction of Series Elastic Components and Some Implications , 1992 .

[22]  J. Houk,et al.  Improvement in linearity and regulation of stiffness that results from actions of stretch reflex. , 1976, Journal of neurophysiology.

[23]  D. Morgan,et al.  Tension as a function of sarcomere length and velocity of shortening in single skeletal muscle fibres of the frog. , 1991, The Journal of physiology.

[24]  G J van Ingen Schenau,et al.  Effects of prestretch at the onset of stimulation on mechanical work output of rat medial gastrocnemius muscle-tendon complex. , 1990, The Journal of experimental biology.

[25]  U Proske,et al.  Tendon stiffness: methods of measurement and significance for the control of movement. A review. , 1987, Journal of biomechanics.

[26]  R. M. Alexander,et al.  Elastic mechanisms in animal movement , 1988 .

[27]  Huijing Pa,et al.  Length-force characteristics of aponeurosis in passive muscle and during isometric and slow dynamic contractions of rat gastrocnemius muscle. , 1988 .

[28]  Gerald H. Pollack,et al.  Contractile Mechanisms in Muscle , 1984, Advances in Experimental Medicine and Biology.

[29]  U. Proske,et al.  Measurements of muscle stiffness and the mechanism of elastic storage of energy in hopping kangaroos. , 1978, The Journal of physiology.

[30]  Peter A. Huijing,et al.  Architecture and Elastic Properties of the Series Elastic Element of Muscle-Tendon Complex , 1990 .

[31]  D. Morgan.  New insights into the behavior of muscle during active lengthening. , 1990, Biophysical journal.

[32]  U Proske,et al.  Stiffness of cat soleus muscle and tendon during activation of part of muscle. , 1984, Journal of neurophysiology.

[33]  S L Woo,et al.  Temperature dependent behavior of the canine medial collateral ligament. , 1987, Journal of biomechanical engineering.

[34]  P A Huijing,et al.  Influence of muscle geometry on shortening speed of fibre, aponeurosis and muscle. , 1992, Journal of biomechanics.

[35]  F. Julian,et al.  Variation of muscle stiffness with force at increasing speeds of shortening , 1975, The Journal of general physiology.

[36]  A F Bennett,et al.  Temperature and muscle. , 1985, The Journal of experimental biology.

[37]  P A Huijing,et al.  Properties of the tendinous structures and series elastic component of EDL muscle-tendon complex of the rat. , 1989, Journal of biomechanics.

[38]  G. Cavagna.  The series elastic component of frog gastrocnemius , 1970, The Journal of physiology.

[39]  R. Blickhan,et al.  Kangaroo rat locomotion: design for elastic energy storage or acceleration? , 1988, The Journal of experimental biology.