Successful Management of Quadruplet Pregnancy following Spontaneous Conception: A Rare Case Report

Introduction : When more than two fetuses simultaneously develop in the uterus, it is called higher order multiple pregnancy. The incidence of such pregnancies ranges from 0.01% to 0.07%. Case report: We report a case of 26-year-old G 2 P 1 L 0 D 2 with previous history of preterm vaginal twin delivery, diagnosed to have quadruplet pregnancy. She was admitted at 28 weeks of gestation for safe confinement. At 33 weeks of gestation, emergency cesarean section was conducted with outcome of two female and two male babies with quadriamniotic and quadrichorionic placenta, without any intra and post-operative complications. Conclusion: A multidisciplinary approach with good neonatal care facilities is warranted for a better outcome in higher order multiple pregnancies. DOI: https://doi.org/10.22502/jlmc.v4i1.88 Journal of Lumbini Medical College. 2016;4(1):46-9

[1]  E. Nwobodo,et al.  Case Report: Spontaneous Monochorionic Tetra‑amniotic Quadruplet Pregnancy at Term , 2013 .

[2]  V. Egwuatu,et al.  Higher-order multiple births in Abakaliki, Southeast Nigeria. , 2011, Singapore medical journal.

[3]  A. Omigbodun,et al.  Term quadruplet pregnancy: a case report , 2010 .

[4]  S. Jahan.  Quadruplet pregnancy : A rare occurrence , 2008 .

[5]  E. Pector.  Ethical Issues of High-order Multiple Births , 2005 .

[6]  M. Keszler,et al.  Triplet Morbidity and Mortality in a Large Case Series , 2003, Journal of Perinatology.

[7]  L. de Catte,et al.  Monochorionic High‐Order Multiple Pregnancies and Multifetal Pregnancy Reduction , 2002, Obstetrics and gynecology.

[8]  J. Obed,et al.  Twin births at University of Maiduguri Teaching Hospital: incidence, pregnancy complications and outcome. , 2002, Nigerian journal of medicine : journal of the National Association of Resident Doctors of Nigeria.

[9]  B. Luke,et al.  Multifetal Pregnancy: A Handbook for Care of the Pregnant Patient , 2000 .

[10]  Z. Abotalb.  Quadruplet pregnancy following a single course of clomiphene citrate. An expensive success. , 2000, Saudi medical journal.

[11]  Z. Abotalib.  Quadruplet pregnancy following a single course of clomiphene citrate , 2000 .

[12]  Contribution of assisted reproductive technology and ovulation-inducing drugs to triplet and higher-order multiple births--United States, 1980-1997. , 2000, MMWR. Morbidity and mortality weekly report.

[13]  F. Broekhuizen,et al.  Spontaneous quadruplet pregnancy in a woman with a personal and family history of spontaneous twin and triplet pregnancy. A case report. , 1994, The Journal of reproductive medicine.

[14]  M. Kiely,et al.  Triplets and higher-order multiple births. Time trends and infant mortality. , 1992, American journal of diseases of children.

[15]  I. Bukovsky,et al.  Triplet, quadruplet and quintuplet pregnancies: Management and outcome , 1992, Acta obstetricia et gynecologica Scandinavica.

[16]  D. Serr,et al.  The improving outcome of triplet pregnancies. , 1989, American journal of obstetrics and gynecology.

[17]  G. Goldman,et al.  Is Elective Cerclage Justified in the Management of Triplet and Quadruplet Pregnancy? , 1989, The Australian & New Zealand journal of obstetrics & gynaecology.