HPV Genotype Distribution among Thai Women with High-Grade CIL and Invasive Cervical Cancer: a Literature Review

More than 90% of worldwide estimated human papillomavirus (HPV)-related cancer mortalities are secondary to invasive cervical cancer (Cutts et al., 2007). There are sufficient evidences to conclude that cervical cancer are virtually caused by complicated infection with high-risk (HR) or carcinogenic types of HPV. According to the recent classification proposed by the International Agency for Research on Cancer, twelve HR-HPV genotypes including type 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, and 59 are classified as one of 114 agents that are carcinogenic to human, or the so-called “group A”(IARC, 2006). As a substantial geographical variation in the HPV genotype distribution has been observed (Li et al., 2011), data regarding HPV type-specific prevalence in each country are therefore mandatory for providing baseline information to predict how the genotype-specific HPV vaccination and HPV-based screening will influence cervical cancer prevention. Accordingly, we evaluated the