Growth Factor Delivery Through Self-assembling Peptide Scaffolds

[1]  A. Grodzinsky,et al.  Controlled delivery of transforming growth factor β1 by self-assembling peptide hydrogels induces chondrogenesis of bone marrow stromal cells and modulates Smad2/3 signaling. , 2011, Tissue engineering. Part A.

[2]  Richard T. Lee,et al.  Intraarticular injection of heparin-binding insulin-like growth factor 1 sustains delivery of insulin-like growth factor 1 to cartilage through binding to chondroitin sulfate. , 2010, Arthritis and rheumatism.

[3]  Richard T. Lee,et al.  Intra-articular Injection of HB-IGF-1 Sustains Delivery of IGF-1 to Cartilage through Binding to Chondroitin Sulfate , 2010 .

[4]  A. Grodzinsky,et al.  Effect of self-assembling peptide, chondrogenic factors, and bone marrow-derived stromal cells on osteochondral repair. , 2010, Osteoarthritis and cartilage.

[5]  A. Grodzinsky,et al.  Self-assembling peptide hydrogels modulate in vitro chondrogenesis of bovine bone marrow stromal cells. , 2010, Tissue engineering. Part A.

[6]  R. Tuan,et al.  A nanofibrous cell‐seeded hydrogel promotes integration in a cartilage gap model , 2009, Journal of tissue engineering and regenerative medicine.

[7]  N. Adachi,et al.  In vitro cartilage formation using TGF-beta-immobilized magnetic beads and mesenchymal stem cell-magnetic bead complexes under magnetic field conditions. , 2010, Journal of biomedical materials research. Part A.

[8]  L. Griffith,et al.  The influence of tethered epidermal growth factor on connective tissue progenitor colony formation. , 2009, Biomaterials.

[9]  R. Brooks,et al.  Articular cartilage tissue engineering: today's research, tomorrow's practice? , 2009, The Journal of bone and joint surgery. British volume.

[10]  Shuguang Zhang,et al.  Controlled release of functional proteins through designer self-assembling peptide nanofiber hydrogel scaffold , 2009, Proceedings of the National Academy of Sciences.

[11]  Shuguang Zhang,et al.  Designer functionalized self-assembling peptide nanofiber scaffolds for growth, migration, and tubulogenesis of human umbilical vein endothelial cells , 2008 .

[12]  R. Kamm,et al.  Primary sequence of ionic self-assembling peptide gels affects endothelial cell adhesion and capillary morphogenesis. , 2008, Journal of biomedical materials research. Part A.

[13]  Richard T Lee,et al.  Engineering insulin‐like growth factor‐1 for local delivery , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[14]  B. Cole,et al.  A randomized trial comparing autologous chondrocyte implantation with microfracture. , 2008, The Journal of bone and joint surgery. American volume.

[15]  Milica Radisic,et al.  Vascular endothelial growth factor immobilized in collagen scaffold promotes penetration and proliferation of endothelial cells. , 2008, Acta biomaterialia.

[16]  R. Stoop Smart biomaterials for tissue engineering of cartilage. , 2008, Injury.

[17]  R. Tuan,et al.  Concepts in gene therapy for cartilage repair. , 2008, Injury.

[18]  Jason A Burdick,et al.  Engineering cartilage tissue. , 2008, Advanced drug delivery reviews.

[19]  C. V. van Blitterswijk,et al.  Critical factors in the design of growth factor releasing scaffolds for cartilage tissue engineering. , 2008, Expert Opinion on Drug Delivery.

[20]  Richard T. Lee,et al.  Local Delivery of Protease-Resistant Stromal Cell Derived Factor-1 for Stem Cell Recruitment After Myocardial Infarction , 2007, Circulation.

[21]  Lars Engebretsen,et al.  A randomized trial comparing autologous chondrocyte implantation with microfracture. Findings at five years. , 2007, The Journal of bone and joint surgery. American volume.

[22]  Byung-Soo Kim,et al.  Enhancement of ectopic bone formation by bone morphogenetic protein-2 released from a heparin-conjugated poly(L-lactic-co-glycolic acid) scaffold. , 2007, Biomaterials.

[23]  Heungsoo Shin,et al.  Matrices and scaffolds for delivery of bioactive molecules in bone and cartilage tissue engineering. , 2007, Advanced drug delivery reviews.

[24]  G. Hsiue,et al.  Heterobifunctional poly(ethylene glycol)-tethered bone morphogenetic protein-2-stimulated bone marrow mesenchymal stromal cell differentiation and osteogenesis. , 2007, Tissue engineering.

[25]  Vivian H. Fan,et al.  Tethered Epidermal Growth Factor Provides a Survival Advantage to Mesenchymal Stem Cells , 2007, Stem cells.

[26]  Fabrizio Gelain,et al.  Biological Designer Self-Assembling Peptide Nanofiber Scaffolds Significantly Enhance Osteoblast Proliferation, Differentiation and 3-D Migration , 2007, PloS one.

[27]  Andrés J. García,et al.  Inhibition of in vitro chondrogenesis in RGD-modified three-dimensional alginate gels. , 2007, Biomaterials.

[28]  Richard T. Lee,et al.  Local myocardial insulin-like growth factor 1 (IGF-1) delivery with biotinylated peptide nanofibers improves cell therapy for myocardial infarction. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[29]  Richard T. Lee,et al.  Controlled delivery of PDGF-BB for myocardial protection using injectable self-assembling peptide nanofibers. , 2005, The Journal of clinical investigation.

[30]  Byung-Soo Kim,et al.  Control of basic fibroblast growth factor release from fibrin gel with heparin and concentrations of fibrinogen and thrombin. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[31]  Jennifer L West,et al.  Covalently immobilized gradients of bFGF on hydrogel scaffolds for directed cell migration. , 2005, Biomaterials.

[32]  Carlos E Semino,et al.  The effect of functionalized self-assembling peptide scaffolds on human aortic endothelial cell function. , 2005, Biomaterials.

[33]  M. Farach-Carson,et al.  Perlecan domain I promotes fibroblast growth factor 2 delivery in collagen I fibril scaffolds. , 2005, Tissue engineering.

[34]  Richard T. Lee,et al.  Injectable Self-Assembling Peptide Nanofibers Create Intramyocardial Microenvironments for Endothelial Cells , 2005, Circulation.

[35]  Joakim Lundeberg,et al.  The biotin‐streptavidin interaction can be reversibly broken using water at elevated temperatures , 2005, Electrophoresis.

[36]  M. Shoichet,et al.  Immobilized concentration gradients of nerve growth factor guide neurite outgrowth. , 2004, Journal of biomedical materials research. Part A.

[37]  Ying E. Zhang,et al.  Smad-dependent and Smad-independent pathways in TGF-β family signalling , 2003, Nature.

[38]  Ralph Müller,et al.  Repair of bone defects using synthetic mimetics of collagenous extracellular matrices , 2003, Nature Biotechnology.

[39]  A. Metters,et al.  Synthetic matrix metalloproteinase-sensitive hydrogels for the conduction of tissue regeneration: Engineering cell-invasion characteristics , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[40]  A. J. Grodzinsky,et al.  Self-assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: Implications for cartilage tissue repair , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[41]  G. Lust,et al.  Insulin-like growth factor-I enhances cell-based repair of articular cartilage. , 2002, The Journal of bone and joint surgery. British volume.

[42]  B. Ursø,et al.  Specificity in ligand binding and intracellular signalling by insulin and insulin-like growth factor receptors. , 2001, Biochemical Society transactions.

[43]  R. Helm,et al.  In vivo biotin supplementation at a pharmacologic dose decreases proliferation rates of human peripheral blood mononuclear cells and cytokine release. , 2001, The Journal of nutrition.

[44]  Jennifer L. West,et al.  Tethered-TGF-β increases extracellular matrix production of vascular smooth muscle cells , 2001 .

[45]  E. Thonar,et al.  Chondrocyte extracellular matrix synthesis and turnover are influenced by static compression in a new alginate disk culture system. , 2000, Archives of biochemistry and biophysics.

[46]  R. Loeser,et al.  Autocrine stimulation by insulin-like growth factor 1 and insulin-like growth factor 2 mediates chondrocyte survival in vitro. , 2000, Arthritis and rheumatism.

[47]  A. Nixon,et al.  Enhanced repair of extensive articular defects by insulin‐like growth factor‐I‐laden fibrin composites , 1999, Journal of Orthopaedic Research.

[48]  Martin L. Yarmush,et al.  Tissue engineering methods and protocols , 1999 .

[49]  L. Griffith,et al.  Preparation and use of tethered ligands as biomaterials and tools for cell biology. , 1999, Methods in molecular medicine.

[50]  H. Bentz,et al.  Improved local delivery of TGF-beta2 by binding to injectable fibrillar collagen via difunctional polyethylene glycol. , 1998, Journal of biomedical materials research.

[51]  I. Kang,et al.  Preparation of insulin-immobilized polyurethanes and their interaction with human fibroblasts. , 1998, Biomaterials.

[52]  J. Wallace,et al.  Des(1-3)IGF-I: a truncated form of insulin-like growth factor-I. , 1996, The international journal of biochemistry & cell biology.

[53]  A. Rich,et al.  Spontaneous assembly of a self-complementary oligopeptide to form a stable macroscopic membrane. , 1993, Proceedings of the National Academy of Sciences of the United States of America.

[54]  P. Benya,et al.  Dihydrocytochalasin B enhances transforming growth factor-beta-induced reexpression of the differentiated chondrocyte phenotype without stimulation of collagen synthesis. , 1993, Experimental cell research.

[55]  A. Grodzinsky,et al.  Fluorometric assay of DNA in cartilage explants using Hoechst 33258. , 1988, Analytical biochemistry.

[56]  R W Farndale,et al.  A direct spectrophotometric microassay for sulfated glycosaminoglycans in cartilage cultures. , 1982, Connective tissue research.