A multimedia, multiple pathway risk assessment of atrazine: the impact of age differentiated exposure including joint uncertainty and variability

Abstract This paper addresses the need to evaluate the differences in exposure to pesticides between children and adults. We present a framework for evaluating these differences in exposure to pesticides through multiple exposure pathways. The concentrations in all environmental media were determined as distributions in a companion paper. All parameter values utilized in the calculation of exposure and risk are considered to be distributions, resulting in distributions for output exposure and risk. A sensitivity analysis was completed to determine the relative importance of the parameters with respect to the outcome. A joint uncertainty and variability analysis was also completed to evaluate the relative contribution between uncertain and variable parameters. Exposure to atrazine by a mid-western farming family is presented as a case study. The predicted exposure for a child based on a 14-year exposure period was 1.6 times that calculated using lifetime averaged exposure parameters. This indicates the importance of considering children as a population sub-group when calculating the exposure and risk to pesticides.

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