Efficient Construction of Pyrazolo[1,5-a]pyrimidine Scaffold and its Exploration as a New Heterocyclic Fluorescent Platform

[1]  Yan‐Chao Wu,et al.  InCl3-Catalyzed Propargylation of Indoles and Phenols with Propargylic Acetates: Application to the Syntheses of Benzofurans and Naphthofurans , 2007 .

[2]  A. Hamilton,et al.  Solvent and pH Effects on the Fluorescence of 7-(Dimethylamino)-2-Fluorenesulfonate , 2007, Journal of Fluorescence.

[3]  B. T. Gregg,et al.  Pyrazolo[1,5-a]pyrimidines. Identification of the privileged structure and combinatorial synthesis of 3-(hetero)arylpyrazolo[1,5-a]pyrimidine-6-carboxamides. , 2007, Journal of combinatorial chemistry.

[4]  Shipra Singh,et al.  Synthesis and Fluorescence Studies of Some New Fluorophores and Their Effect on Hybridization of Oligodeoxyribonucleotides , 2007, Journal of Fluorescence.

[5]  Yan‐Chao Wu,et al.  Synthesis of Trifluoromethyl-Promoted Functional Pyrazolo[1,5-a]pyrimidine and Pyrazolo[5,1-d][1,2,3,5]tetrazine-4(3H)-ones. , 2006 .

[6]  Yan‐Chao Wu,et al.  Skraup−Doebner−Von Miller Quinoline Synthesis Revisited: Reversal of the Regiochemistry for γ-Aryl-β,γ-unsaturated α-Ketoesters , 2006 .

[7]  Yan‐Chao Wu,et al.  Skraup-Doebner-Von Miller quinoline synthesis revisited: reversal of the regiochemistry for gamma-aryl-beta,gamma-unsaturated alpha-ketoesters. , 2006, The Journal of organic chemistry.

[8]  C. Martini,et al.  A novel selective GABA(A) alpha1 receptor agonist displaying sedative and anxiolytic-like properties in rodents. , 2005, Journal of medicinal chemistry.

[9]  S. Shevelev,et al.  Liquid‐Phase Synthesis of Combinatorial Libraries Based on 7‐Trifluoromethyl‐Substituted Pyrazolo[1,5‐a]pyrimidine Scaffold. , 2005 .

[10]  Li Liu,et al.  3-(4-Methoxystyryl)-2 H -1,4-benzoxazin-2-one , 2005 .

[11]  S. Shevelev,et al.  Liquid-phase synthesis of combinatorial libraries based on 7-trifluoromethyl-substituted pyrazolo[1,5-a]pyrimidine scaffold. , 2005, Journal of combinatorial chemistry.

[12]  B. Katzenellenbogen,et al.  Pyrazolo[1,5-a]pyrimidines: estrogen receptor ligands possessing estrogen receptor beta antagonist activity. , 2004, Journal of medicinal chemistry.

[13]  Xin-jun Liu,et al.  Design of 2,5-dimethyl-3-(6-dimethyl-4-methylpyridin-3-yl)-7-dipropylaminopyrazolo[1,5-a]pyrimidine (NBI 30775/R121919) and structure--activity relationships of a series of potent and orally active corticotropin-releasing factor receptor antagonists. , 2004, Journal of medicinal chemistry.

[14]  J. A. Smith,et al.  Acridones and Quinacridones: Novel Fluorophores for Fluorescence Lifetime Studies , 2004, Journal of Fluorescence.

[15]  W. F. Hoffman,et al.  Optimization of a pyrazolo[1,5-a]pyrimidine class of KDR kinase inhibitors: improvements in physical properties enhance cellular activity and pharmacokinetics. , 2002, Bioorganic & medicinal chemistry letters.

[16]  K. Rurack,et al.  Rigidization, Preorientation and Electronic Decoupling — The “Magic Triangle” for the Design of Highly Efficient Fluorescent Sensors and Switches , 2002 .

[17]  Eric V Anslyn,et al.  Sensing A Paradigm Shift in the Field of Molecular Recognition: From Selective to Differential Receptors. , 2001, Angewandte Chemie.

[18]  C. Almansa,et al.  Synthesis and SAR of a new series of COX-2-selective inhibitors: pyrazolo[1,5-a]pyrimidines. , 2001, Journal of medicinal chemistry.

[19]  J. García-Rafanell,et al.  New Azole Antifungals. Part 2. Synthesis and Antifungal Activity of Heterocyclecarboxamide Derivatives of 3-Amino-2-aryl-1-azolyl-2-butanol. , 1998 .

[20]  J Ramis,et al.  New azole antifungals. 2. Synthesis and antifungal activity of heterocyclecarboxamide derivatives of 3-amino-2-aryl-1-azolyl-2-butanol. , 1998, Journal of medicinal chemistry.

[21]  C. T. Chen,et al.  Fluorescent, sequence-selective peptide detection by synthetic small molecules. , 1998, Science.

[22]  N. Yamamoto,et al.  Effect of FR143430, a novel cytokine suppressive agent, on adenocarcinoma colon26-induced cachexia in mice. , 1998, Anticancer research.

[23]  W. Ried,et al.  Synthesis of new substituted pyrazolo[1,5-a]-pyrimidines and pyrazolo[1,5-a]1,3,5-triazines , 1988 .

[24]  R. Coates,et al.  .alpha.-Alkoxyallylation of activated carbonyl compounds. A novel variant of the Michael reaction , 1984 .

[25]  J. Lakowicz Principles of fluorescence spectroscopy , 1983 .