Effect of a new cognition enhancer, alpha-glycerylphosphorylcholine, on scopolamine-induced amnesia and brain acetylcholine

[1]  G. Abbiati,et al.  High-performance liquid chromatographic assay of L-alpha-glycerophosphorylcholine using a two-step enzymic conversion. , 1991, Journal of chromatography.

[2]  V. Cuomo,et al.  Effects of alpha-glycerylphosphorylcholine (alpha-GPC) and phosphatidylcholine (PC) on the electrocorticogram (ECoG) in the rat , 1990 .

[3]  M. Trabucchi,et al.  Regulation of phorbol ester binding and protein kinase C activity in aged rat brain , 1990, Neurobiology of Aging.

[4]  M. Packard,et al.  Post-training injection of the acetylcholine M2 receptor antagonist AF-DX 116 improves memory , 1990, Brain Research.

[5]  M. Trabucchi,et al.  Omegaconotoxin binding decreases in aged rat brain , 1990, Neurobiology of Aging.

[6]  J. Gray,et al.  Low dose tetrahydroaminoacridine (THA) improves cognitive function but does not affect brain acetylcholine in rats , 1990, Pharmacology Biochemistry and Behavior.

[7]  E. Giacobini,et al.  Present state and future development of the therapy of Alzheimer disease , 1990, Aging.

[8]  S. Gauthier,et al.  Tetrahydroaminoacridine-lecithin combination treatment in patients with intermediate-stage Alzheimer's disease. Results of a Canadian double-blind, crossover, multicenter study. , 1990, The New England journal of medicine.

[9]  G. Kawanishi,et al.  Central muscarinic activities of an M1-selective agonist: preferential effect on reversal of amnesia , 1990, Brain Research.

[10]  M. Tohyama,et al.  An attempt to cause the selective loss of the cholinergic neurons in the basal forebrain of the rat: A new animal model of Alzheimer's disease , 1989, Neuroscience Letters.

[11]  I. Izquierdo,et al.  Mechanism of action of scopolamine as an amnestic. , 1989, Trends in pharmacological sciences.

[12]  M. Trabucchi,et al.  Chronic alcohol intake modifies phorbol ester binding in selected rat brain areas. , 1989, Alcohol.

[13]  J. Coyle,et al.  Effects of continuous infusion of cholinergic drugs on memory impairment in rats with basal forebrain lesions. , 1989, The Journal of pharmacology and experimental therapeutics.

[14]  M. Trabucchi,et al.  Acute ethanol and acetaldehyde administration produce similar effects on L-type calcium channels in rat brain. , 1988, Alcohol.

[15]  J. Buccafusco,et al.  An evaluation of the mechanism of scopolamine-induced impairment in two passive avoidance protocols , 1988, Pharmacology Biochemistry and Behavior.

[16]  M. Piercey,et al.  Reversal of scopolamine-induced amnesia and alterations in energy metabolism by the nootropic piracetam: implications regarding identification of brain structures involved in consolidation of memory traces , 1987, Brain Research.

[17]  K. Davis,et al.  RS 86 in the treatment of alzheimer's disease: Cognitive and biological effects , 1987, Biological Psychiatry.

[18]  G. Pepeu,et al.  Interactions between oxiracetam, aniracetam and scopolamine on behavior and brain acetylcholine , 1987, Pharmacology Biochemistry and Behavior.

[19]  A. Kling,et al.  Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type. , 1986, The New England journal of medicine.

[20]  G. Pepeu,et al.  Oxiracetam prevents electroshock-induced decrease in brain acetylcholine and amnesia. , 1986, European journal of pharmacology.

[21]  G. Damsma,et al.  A Simple, Sensitive, and Economic Assay for Choline and Acetylcholine Using HPLC, an Enzyme Reactor, and an Electrochemical Detector , 1985, Journal of neurochemistry.

[22]  D. Olton,et al.  Lesions in nucleus basalis magnocellularis and medial septal area of rats produce qualitatively similar memory impairments , 1985, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[23]  R. Bartus,et al.  Behavioral and neurochemical effects following neurotoxic lesions of a major cholinergic input to the cerebral cortex in the rat , 1983, Pharmacology Biochemistry and Behavior.

[24]  D L Price,et al.  Alzheimer's disease: a disorder of cortical cholinergic innervation. , 1983, Science.

[25]  G. Pepeu,et al.  Lesions of cholinergic forebrain nuclei: Changes in avoidance behavior and scopolamine actions , 1982, Pharmacology Biochemistry and Behavior.

[26]  S. Zornetzer,et al.  Memory and postsynaptic cholinergic receptors in aging mice , 1982, Pharmacology Biochemistry and Behavior.

[27]  R. Bartus,et al.  The cholinergic hypothesis of geriatric memory dysfunction. , 1982, Science.

[28]  J. Coyle,et al.  Alzheimer's disease and senile dementia: loss of neurons in the basal forebrain. , 1982, Science.

[29]  B. M. Brown,et al.  Practical Non-Parametric Statistics. , 1981 .

[30]  R. Bartus,et al.  Age-related changes in passive avoidance retention: modulation with dietary choline. , 1980, Science.

[31]  S. Gauthier,et al.  CLINICAL EFFECTS OF CHOLINE IN ALZHEIMER'S DISEASE , 1978, The Lancet.

[32]  W. Kruskal,et al.  Use of Ranks in One-Criterion Variance Analysis , 1952 .

[33]  Oliver H. Lowry,et al.  Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.

[34]  E. Perry.  The cholinergic hypothesis--ten years on. , 1986, British medical bulletin.

[35]  U. Schindler,et al.  Nootropic drugs: Animal models for studying effects on cognition , 1984 .

[36]  S. Zeisel.  Dietary choline: biochemistry, physiology, and pharmacology. , 1981, Annual review of nutrition.