PTTG1 alleviates acute alcoholic liver injury by inhibiting endoplasmic reticulum stress‐induced hepatocyte pyroptosis

Heavy drinking is a primary cause of alcoholic liver injury (ALI). Pituitary tumour transforming gene 1 (PTTG1) is involved in the occurrence and development of hepatocellular carcinoma (HCC), which is a well‐known inflammation‐related cancer with various aetiologies, including alcohol consumption. However, the role of PTTG1 in alcohol‐induced liver injury and inflammation is not clear.

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