Banding pattern of human chromosomes.
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STUDIES of mammalian chromosomes have advanced rapidly since the introduction of the quinacrine fluorescence technique1 and other procedures which are believed to locate repetitive DNA sequences in cytological chromosome preparations2,3. To improve these techniques, a method has been developed which can provide further information about chromosome organization.
[1] P. Nowell,et al. Chromosome preparations of leukocytes cultured from human peripheral blood. , 1960, Experimental cell research.
[2] J. Gall,et al. Chromosomal Localization of Mouse Satellite DNA , 1970, Science.