A Case of Small-cell Carcinoma of the Larynx

A case of small-cell carcinoma of the larynx was reported in this paper. The patient was a 48-year-old man who had complained of hoarseness and a sore throat. The left false vocal fold had bulged out presented a smooth surface. A CT scan revealed a 2×1.5×3cm submucosal tumor with relatively clear boundaries. A biopsy from the larynx through an operating microscope suggested pleomorphic adenoma or malignancy. Because of a high level of SCC antigen and NSE, the whole tumor was removed. The final histopathological diagnosis was small-cell carcinoma of the larynx. Although the tumor disappeared after the operation and postoperative radiotherapy (linac 60 Gy) for six months, the patient had a metastatic swelling of the right cervical lymph node. A right functional neck dissection and two courses of chemotherapy (carboplatine 450 mg and etoposide 150 mg) have kept the patient alive with no recurrence or distance metastasis for three years. As a result, surgical treatment of small-cell carcinoma was thought to have a curative potential for localized lesions.

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