Applicability of the histidine–tryptophan–ketoglutarate solution as a machine perfusion solution for marginal liver grafts

There are very few reports comparing the use of the University of Wisconsin solution and histidine–tryptophan–ketoglutarate solution as machine perfusion solutions for marginal liver grafts. We aimed to clarify whether the use of the histidine–tryptophan–ketoglutarate solution in hypothermic machine perfusion improves the split‐liver graft function in a large animal model.

[1]  H. Yokoo,et al.  Beneficial effects of end-ischemic oxygenated machine perfusion preservation for split-liver transplantation in recovering graft function and reducing ischemia–reperfusion injury , 2021, Scientific Reports.

[2]  R. Angelico,et al.  The New Horizon of Split‐Liver Transplantation: Ex Situ Liver Splitting During Hypothermic Oxygenated Machine Perfusion , 2020, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[3]  A. Shimizu,et al.  Small-for-size syndrome in liver transplantation: Definition, pathophysiology and management. , 2020, Hepatobiliary & pancreatic diseases international : HBPD INT.

[4]  H. Furukawa,et al.  Applicability of Hypothermic Oxygenate Machine Perfusion Preservation for Split-Liver Transplantation in a Porcine Model: An Experimental Study , 2020, Annals of transplantation.

[5]  Peony D. Banik,et al.  Split-Liver Ex Situ Machine Perfusion: A Novel Technique for Studying Organ Preservation and Therapeutic Interventions , 2020, Journal of clinical medicine.

[6]  J. Tremblay.  Through thick and thin: The interdependence of blood viscosity, shear stress and endothelial function , 2019, Experimental physiology.

[7]  S. Enosawa,et al.  Evaluation Using an Isolated Reperfusion Model for Porcine Liver Donated After Cardiac Death Preserved with Oxygenated Hypothermic Machine Perfusion , 2018, Annals of transplantation.

[8]  G. Camussi,et al.  Porcine Isolated Liver Perfusion for the Study of Ischemia Reperfusion Injury: A Systematic Review , 2018, Transplantation.

[9]  S. Enosawa,et al.  Ex Vivo Reperfusion Model to Evaluate Utility of Machine Preservation for Porcine Liver Donated After Cardiac Death. , 2018, Transplantation proceedings.

[10]  E. Mohammadi,et al.  Barriers and facilitators related to the implementation of a physiological track and trigger system: A systematic review of the qualitative evidence , 2017, International journal for quality in health care : journal of the International Society for Quality in Health Care.

[11]  Charles M. Miller,et al.  Split liver transplantation in adults , 2016, World journal of gastroenterology.

[12]  A. Shah,et al.  Regulation of endothelial homeostasis, vascular development and angiogenesis by the transcription factor ERG , 2016, Vascular pharmacology.

[13]  A. Dalal.  Split liver transplantation: What's unique? , 2015, World journal of transplantation.

[14]  Haiyang Xie,et al.  Influence of perfusate on liver viability during hypothermic machine perfusion. , 2015, World journal of gastroenterology.

[15]  T. Minor,et al.  Hypothermic reconditioning in organ transplantation , 2013, Current opinion in organ transplantation.

[16]  P. Clavien,et al.  Protective mechanisms of end-ischemic cold machine perfusion in DCD liver grafts. , 2013, Journal of hepatology.

[17]  Y. Kanda,et al.  Investigation of the freely available easy-to-use software ‘EZR' for medical statistics , 2012, Bone Marrow Transplantation.

[18]  Alexander Y. Petrenko,et al.  Organ Preservation: Current Concepts and New Strategies for the Next Decade , 2011, Transfusion Medicine and Hemotherapy.

[19]  T. Minor,et al.  Optimal Time for Hypothermic Reconditioning of Liver Grafts by Venous Systemic Oxygen Persufflation in a Large Animal Model , 2011, Transplantation.

[20]  P. Evans,et al.  The Transcription Factor Erg Inhibits Vascular Inflammation by Repressing NF-&kgr;B Activation and Proinflammatory Gene Expression in Endothelial Cells , 2011, Arteriosclerosis, thrombosis, and vascular biology.

[21]  R. Mangus,et al.  Clinical experience with histidine‐tryptophan‐ketoglutarate solution in abdominal organ preservation: a review of recent literature , 2009, Clinical transplantation.

[22]  M. Bhasin,et al.  Antiinflammatory Effects of the ETS Factor ERG in Endothelial Cells Are Mediated Through Transcriptional Repression of the Interleukin-8 Gene , 2009, Circulation research.

[23]  A. Demetris,et al.  Liver Transplantation Using Donation After Cardiac Death Donors: Long‐Term Follow‐Up from a Single Center , 2009, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[24]  U. Neumann,et al.  Improved microcirculation by low‐viscosity histidine– tryptophan–ketoglutarate graft flush and subsequent cold storage in University of Wisconsin solution: results of an orthotopic rat liver transplantation model , 2008, Transplant international : official journal of the European Society for Organ Transplantation.

[25]  B. Mattice,et al.  Comparative analysis of clinical efficacy and cost between University of Wisconsin solution and histidine-tryptophan-ketoglutarate. , 2008, Progress in transplantation.

[26]  P. Clavien,et al.  Machine Perfusion for ‘Marginal’ Liver Grafts , 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[27]  M. Englesbe,et al.  Comparison of Histidine‐Tryptophan‐Ketoglutarate and University of Wisconsin Preservation in Renal Transplantation , 2008, American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons.

[28]  Liang Du,et al.  Histidine‐tryptophan‐ketoglutarate solution vs. University of Wisconsin solution for liver transplantation: A systematic review , 2007, Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society.

[29]  B. Fuller,et al.  Hypothermic perfusion preservation: the future of organ preservation revisited? , 2007, Cryobiology.

[30]  M. Orloff,et al.  University of Wisconsin versus histidine-tryptophan-ketoglutarate for tissue preservation in live-donor liver transplantation. , 2006, Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation.

[31]  Gerhard Rakhorst,et al.  Effect of University of Wisconsin organ-preservation solution on haemorheology , 2004, Transplant international : official journal of the European Society for Organ Transplantation.

[32]  J. Lemasters,et al.  Role of the mitochondrial permeability transition in apoptotic and necrotic death after ischemia/reperfusion injury to hepatocytes. , 2003, Current molecular medicine.

[33]  S. Baicu,et al.  Acid-base buffering in organ preservation solutions as a function of temperature: new parameters for comparing buffer capacity and efficiency. , 2002, Cryobiology.

[34]  M. Menger,et al.  Warm preflush with streptokinase improves microvascular procurement and tissue integrity in liver graft retrieval from non-heart-beating donors. , 2000, Transplantation.

[35]  Shohachi Suzuki,et al.  THE BENEFICIAL EFFECT OF A PROSTAGLANDIN 12 ANALOG ON ISCHEMIC RAT LIVER , 1991, Transplantation.

[36]  R. Stratta,et al.  Combined cold storage-perfusion preservation of the kidney with a new synthetic perfusate. , 1989, Transplantation Proceedings.

[37]  Peter C. Hollenhorst,et al.  Expression profiles frame the promoter specificity dilemma of the ETS family of transcription factors. , 2004, Nucleic acids research.

[38]  R. Pichlmayr,et al.  [Transplantation of a donor liver to 2 recipients (splitting transplantation)--a new method in the further development of segmental liver transplantation]. , 1988, Langenbecks Archiv fur Chirurgie.